Search Results - "Ji, Dengbo"

Design and synthesis of doublecortin-like kinase 1 inhibitors and their bioactivity evaluation by Pan, Pengming, Ji, Dengbo, Li, Zhongjun, Meng, Xiangbao

“…Doublecortin-like kinase 1 (DCLK) is a microtubule-associated serine/threonine kinase that is upregulated in a wide range of cancers and is believed to be…”
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Combination of radiotherapy and suppression of Tregs enhances abscopal antitumor effect and inhibits metastasis in rectal cancer by Ji, Dengbo, Song, Can, Li, Yongheng, Xia, Jinhong, Wu, Yanjing, Jia, Jinying, Cui, Xinxin, Yu, Songmao, Gu, Jin

“…BackgroundDistant metastasis is the major cause of mortality in patients with locally advanced rectal cancer (LARC) following neoadjuvant chemoradiotherapy…”
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MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1 by Ji, Dengbo, Chen, Zhiguo, Li, Ming, Zhan, Tiancheng, Yao, Yunfeng, Zhang, Zhiqian, Xi, Jianzhong, Yan, Li, Gu, Jin

“…Given the emerging role of microRNA in tumor disease progression, we investigated the association between microRNA expression, liver metastasis and prognosis…”
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Overexpression of LAMC2 predicts poor prognosis in colorectal cancer patients and promotes cancer cell proliferation, migration, and invasion by Huang, Dandan, Du, Changzheng, Ji, Dengbo, Xi, Jianzhong, Gu, Jin

“…Laminin γ2 (LAMC2) has been reported to be involved in the development and progression of a variety of tumors. However, its function in human colorectal cancer…”
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Predictive value of proteomic markers for advanced rectal cancer with neoadjuvant chemoradiotherapy by Wang, Hanyang, Ji, Dengbo, Tian, Huifang, Gao, Zhaoya, Song, Can, Jia, Jinying, Cui, Xinxin, Zhong, Lijun, Shen, Jing, Gu, Jin

“…Abstract Background Preoperative neoadjuvant chemoradiation (nCRT) has been the standard treatment for locally advanced rectal cancer. Serum biomarkers to…”
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FAP promotes metastasis and chemoresistance via regulating YAP1 and macrophages in mucinous colorectal adenocarcinoma by Ji, Dengbo, Jia, Jinying, Cui, Xinxin, Li, Zhaowei, Wu, Aiwen

“…Mucinous colorectal adenocarcinoma (MC) is less likely to respond to chemotherapy and is associated with poorer prognosis compared with non-MC (NMC)…”
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Enhancement of Sensitivity to Chemo/Radiation Therapy by Using miR-15b against DCLK1 in Colorectal Cancer by Ji, Dengbo, Zhan, Tiancheng, Li, Ming, Yao, Yunfeng, Jia, Jinying, Yi, Haizhao, Qiao, Meng, Xia, Jinhong, Zhang, Zhiqian, Ding, Huirong, Song, Can, Han, Yong, Gu, Jin

“…Chemo-/radiotherapy resistance is the main cause accounting for most treatment failure in colorectal cancer (CRC). Tumor-initiating cells (TICs) are the…”
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Glycan analysis of colorectal cancer samples reveals stage-dependent changes in CEA glycosylation patterns by Zhao, Qianqian, Zhan, Tiancheng, Deng, Zaian, Li, Qianqian, Liu, Yaming, Yang, Shaojie, Ji, Dengbo, Li, Yan

“…Carcinoembryonic antigen (CEA) is a glycoprotein associated with colorectal cancer (CRC). While the functions of its gene and protein have been fully…”
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Prognostic role of serum AZGP1, PEDF and PRDX2 in colorectal cancer patients by Ji, Dengbo, Li, Ming, Zhan, Tiancheng, Yao, Yunfeng, Shen, Jing, Tian, Huifang, Zhang, Zhiqian, Gu, Jin

“…This study was designed to develop novel and better reliable serum prognostic biomarkers for colorectal cancer (CRC). A 50 sample set including CRC, adenoma…”
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Hemolysin BL from novel Bacillus toyonensis BV-17 induces antitumor activity both in vitro and in vivo by Chen, Jiajia, Hu, Shoukui, Ji, Dengbo, Gao, Zhaoya, Wang, Hanyang, Yang, Yong, Chen, Yongkang, Gu, Jin

“…The gut microbiota plays an important role in cancer development and immunotherapy. Bacterial toxins have enormous antitumor potential due to their…”
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Serum-based microRNA signature predicts relapse and therapeutic outcome of adjuvant chemotherapy in colorectal cancer patients by Ji, Dengbo, Qiao, Meng, Yao, Yunfeng, Li, Ming, Chen, Hailong, Dong, Qi, Jia, Jinying, Cui, Xinxin, Li, Zhaowei, Xia, Jinhong, Gu, Jin

“…Approximately 60% of patients with colorectal cancer (CRC) undergo either local recurrence or distant metastases after surgery. Current prognostic biomarkers…”
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Surgery may not benefit patients with locally advanced rectal cancer who achieved clinical complete response following neoadjuvant chemoradiotherapy by Han, Zihan, Li, Ming, Chen, Jiajia, Ji, Dengbo, Zhan, Tiancheng, Peng, Yifan, Xue, Weicheng, Li, Yongheng, Cai, Yong, Sun, Yingshi, Wu, Qi, Du, Changzheng, Gu, Jin

“…We compared the long-term outcome of the watch and wait (WW) strategy and surgery in patients with locally advanced rectal cancer. This prospective cohort…”
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The implications from the interplay of neoadjuvant chemoradiotherapy and the immune microenvironment in rectal cancer by Shi, Mengyuan, Chen, Yongkang, Ji, Dengbo

“…Neoadjuvant chemoradiotherapy (nCRT) is recommended for the treatment of locally advanced rectal cancer. Even though the combination of nCRT and immune…”
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Combination of Radiotherapy and Anti-CD25 Enhances Local and Abscopal Combination of Radiotherapy and Anti-CD25 Enhances Local and Abscopal Antitumor Effects in Rectal Cancer by Gao, Zhaoya, Gu, Jin, Ji, Dengbo

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Abstract 2430: HOXC6 promotes tumorigenesis of right-sided colon cancer by li, Xin, Xia, Jinhong, Ji, Dengbo, Gu, Jin

“…Abstract Colorectal cancer (CRC) is a common malignant tumor of the digestive tract, with high heterogeneity. The significant difference in prognosis and…”
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Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5 by Pan, Pengming, Geng, Tongtong, Li, Zhongtang, Ding, Xuyang, Shi, Mengyuan, Li, Yang, Wang, Yashuai, Shi, Yuanyuan, Wu, Jiaojiao, Zhong, Liang, Ji, Dengbo, Li, Zhongjun, Meng, Xiangbao

“…Extracellular signal-regulated kinase 5 (ERK5) is recognized as a key member of the mitogen-activated protein kinase family and is involved in tumor growth,…”
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Tumor mutation burden in blood predicts benefit from neoadjuvant chemo/radiotherapy in locally advanced rectal cancer by Ji, Dengbo, Zhang, Dakui, Zhan, Tiancheng, Jia, Jinying, Han, Wenbo, Li, Zhaowei, Li, Ming, Song, Can, Wang, Jianfei, Gu, Jin

“…Distant metastasis has been the major concern of prognosis in patients with locally advanced rectal cancer (LARC). The purpose of this study was to investigate…”
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UVRAG Promotes Tumor Progression through Regulating SP1 in Colorectal Cancer by Shi, Mengyuan, An, Guo, Chen, Nan, Jia, Jinying, Cui, Xinxin, Zhan, Tiancheng, Ji, Dengbo

“…Colorectal cancer (CRC) is the third most common type of cancer. The ultraviolet radiation resistance-associated gene (UVRAG) plays a role in autophagy and has…”
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Total Neoadjuvant Therapy With PD-1 Blockade for High-Risk Proficient Mismatch Repair Rectal Cancer by Li, Yingjie, Pan, Chaohu, Gao, Yuye, Zhang, Li, Ji, Dengbo, Cui, Xiaoli, Zhang, Xiaoyan, Cai, Yong, Zhang, Yangzi, Yao, Yunfeng, Wang, Lin, Leng, Jiahua, Zhan, Tiancheng, Wu, Dongfang, Gao, Zhibo, Sun, Ying-Shi, Li, Zhongwu, Luo, Haitao, Wu, Aiwen

“…Total neoadjuvant therapy (TNT) is the standard treatment for locally advanced rectal cancer, especially for patients with high-risk factors. However, the…”
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PKUCH 04 trial: Total neoadjuvant chemoradiation combined with neoadjuvant PD-1 blockade for pMMR/MSS locally advanced middle to low rectal cancer by WU, Aiwen, Li, Yingjie, Ji, Dengbo, Zhang, Li, Zhang, Xiaoyan, Cai, Yong, Zhang, Yangzi, Yao, Yunfeng, Wang, Lin, Leng, Jiahua, Zhan, Tiancheng, Sun, Ying-Shi, Li, Zhongwu

“…3609 Background: Total neoadjuvant therapy (TNT) with induction chemotherapy and chemoradiation is the standard of care for locally advanced rectal cancers…”
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