Search Results - "Ji, Chunmei"
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Efficacy and safety of thrombolysis for acute ischemic stroke with atrial fibrillation: a meta-analysis
Published in BMC neurology (11-02-2021)“…The efficacy and safety of intravenous thrombolysis (IVT) for acute ischemic stroke with atrial fibrillation (AF) is still controversial. We conducted a…”
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Post-marketing drug safety surveillance of enfortumab vedotin: an observational pharmacovigilance study based on a real-world database
Published in Frontiers in immunology (20-08-2024)“…Enfortumab vedotin (EV) is an antibody-drug conjugate (ADC) that has been approved by the FDA for patients with locally advanced or metastatic urothelial…”
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A real-world disproportionality analysis of apalutamide: data mining of the FDA adverse event reporting system
Published in Frontiers in pharmacology (05-06-2023)“…Apalutamide is a new drug class, which is approved to treat prostate cancer (PCa). The aim of our study was to assess the safety profiles of apalutamide in…”
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Clinical and economic impact of pharmacist interventions on sampled outpatient prescriptions in a Chinese teaching hospital
Published in BMC health services research (04-07-2018)“…Limited studies have evaluated the effectiveness of pharmacist interventions on outpatient prescription. The goal of this study was to evaluate the clinical…”
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NKTR-358: A novel regulatory T-cell stimulator that selectively stimulates expansion and suppressive function of regulatory T cells for the treatment of autoimmune and inflammatory diseases
Published in Journal of translational autoimmunity (Online) (01-01-2021)“…Impaired interleukin-2 (IL-2) production and regulatory T-cell dysfunction have been implicated as immunological mechanisms central to the pathogenesis of…”
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Degradation of 4-methylbenzylidene camphor (4-MBC) Using Fenton, UV Light Irradiation and Photo-Fenton
Published in MATEC Web of Conferences (01-01-2017)“…As one of the most commonly employed UV-filters, 4-methylbenzylidene camphor (4-MBC) has been shown to accumulate in the environment and have endocrine…”
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Journal Article Conference Proceeding -
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Adverse event profiles of PCSK9 inhibitors alirocumab and evolocumab: Data mining of the FDA adverse event reporting system
Published in British journal of clinical pharmacology (01-12-2022)“…Background Proprotein convertase subtilisin/kexin type (PCSK9) inhibitor is a new drug class approved for treating dyslipidemias. Herein, we aimed to…”
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miR-93 enhances hepatocellular carcinoma invasion and metastasis by EMT via targeting PDCD4
Published in Biotechnology letters (01-11-2017)“…Objectives To clarify the potential biological function of miR-93 and its related molecular mechanism underlying metastasis in human hepatocellular carcinoma…”
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NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models
Published in Clinical cancer research (01-02-2016)“…Aldesleukin, recombinant human IL2, is an effective immunotherapy for metastatic melanoma and renal cancer, with durable responses in approximately 10% of…”
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Quercetin alleviates thermal and cold hyperalgesia in a rat neuropathic pain model by inhibiting Toll-like receptor signaling
Published in Biomedicine & pharmacotherapy (01-10-2017)“…Neuropathic pain is caused by lesion or disease of the nervous system, which results in abnormal spontaneous and evoked pain. It’s common in clinical practice…”
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Non-use of health care service among empty-nest elderly in Shandong, China: a cross-sectional study
Published in BMC health services research (29-07-2015)“…Empty-nest elderly refers to those elderly with no children or whose children have already left home. Few studies have focused on healthcare service use among…”
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Sphingosine kinase inhibitors: A patent review
Published in International journal of molecular medicine (01-05-2018)“…Sphingosine kinases (SphKs) catalyze the conversion of the sphingosine to the promitogenic/migratory product, sphingosine-1-phosphate (S1P). SphK/S1P pathway…”
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Abstract A95: NKTR-214, a novel CD122-biased immunostimulatory cytokine, does not cause hypotension in non-human primates despite greater cytokine exposure than achieved with high dose Interleukin-2 (HD-IL-2)
Published in Molecular cancer therapeutics (01-12-2015)“…Abstract Background: IL-2 was the first cancer immunotherapy approved, producing durable responses in ∼10% of patients treated for metastatic melanoma and…”
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Inhibitors targeting the SUMOylation pathway: A patent review 2012‑2015 (Review)
Published in International journal of molecular medicine (01-01-2018)“…Small ubiquitin‑related modifier (SUMO) proteins bind to the lysine residue of target proteins to produce functionally mature proteins. The abnormal…”
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In Utero and Postnatal Effects of Sidestream Cigarette Smoke Exposure on Lung Function, Hyperresponsiveness, and Neuroendocrine Cells in Rats
Published in Toxicology and applied pharmacology (01-05-1995)“…We evaluated whether sidestream smoke (SS) exposure in utero and/or postnatally causes airway obstruction and hyperresponsiveness, and whether the effect is…”
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Etirinotecan pegol administration is associated with lower incidences of neutropenia compared to irinotecan administration
Published in Cancer chemotherapy and pharmacology (01-01-2017)“…Purpose The relationship between incidences of neutropenia and 10-hydroxy-7-ethyl camptothecin (SN38) exposure was explored using SN38 pharmacokinetic and…”
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Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis
Published in Experimental and therapeutic medicine (01-07-2018)“…The serum triggering receptor expressed on myeloid cell (TREM)-like transcription factor-1 [soluble TREM-like transcript-1 (STLT-1)] and bilirubin levels were…”
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Abstract B296: NKTR-214: An immunotherapy with altered selectivity at the IL2 receptor; pharmacokinetics (PK) and pharmacodynamics (PD) in animal models
Published in Molecular cancer therapeutics (01-11-2013)“…Abstract Background: Aldesleukin (IL2) has been successfully used to treat cancer, with the potential for durable responses. However, its efficacy is limited…”
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Conceptual Research Model of Developing the Decision Support System for Agriculture Under Uncertainty
Published in 2021 IEEE International Conference on Smart Information Systems and Technologies (SIST) (28-04-2021)“…In the context of growing human needs for food, an important issue is to increase the efficiency of agricultural enterprises. A modern tool for efficiency is…”
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Conference Proceeding -
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Ocotillol-type derivatives (II) synthesis and protective effects on cultured anoxia/reoxygen injury myocardiocytes
Published in Journal of medicinal plant research (23-12-2011)Get full text
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