Search Results - "Jhaveri, K"

HER2-positive advanced breast cancer: optimizing patient outcomes and opportunities for drug development by Singh, J C, Jhaveri, K, Esteva, F J

“…Effective targeting of the human epidermal growth factor receptor 2 (HER2) has changed the natural history of HER2 overexpressing (HER2+) metastatic breast…”
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Characterization of on-target adverse events caused by TRK inhibitor therapy by Liu, D., Flory, J., Lin, A., Offin, M., Falcon, C.J., Murciano-Goroff, Y.R., Rosen, E., Guo, R., Basu, E., Li, B.T., Harding, J.J., Iyer, G., Jhaveri, K., Gounder, M.M., Shukla, N.N., Roberts, S.S., Glade-Bender, J., Kaplanis, L., Schram, A., Hyman, D.M., Drilon, A.

“…The tropomyosin receptor kinase (TRK) pathway controls appetite, balance, and pain sensitivity. While these functions are reflected in the on-target adverse…”
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Ado-trastuzumab emtansine (T-DM1) in patients with HER2-amplified tumors excluding breast and gastric/gastroesophageal junction (GEJ) adenocarcinomas: results from the NCI-MATCH trial (EAY131) subprotocol Q by Jhaveri, K.L., Wang, X.V., Makker, V., Luoh, S.-W., Mitchell, E.P., Zwiebel, J.A., Sharon, E., Gray, R.J., Li, S., McShane, L.M., Rubinstein, L.V., Patton, D., Williams, P.M., Hamilton, S.R., Conley, B.A., Arteaga, C.L., Harris, L.N., O’Dwyer, P.J., Chen, A.P., Flaherty, K.T.

“…The National Cancer Institute—Molecular Analysis for Therapy Choice (NCI-MATCH) is a national precision medicine study incorporating centralized genomic…”
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Hepatocellular adenoma subtyping by qualitative MRI features and machine learning algorithm of integrated qualitative and quantitative features: a proof-of-concept study by Liu, X, Espin-Garcia, O, Khalvati, F, Namdar, K, Fischer, S, Haider, M A, Jhaveri, K S

“…To evaluate hepatocellular adenoma (HCA) subtyping using qualitative magnetic resonance imaging (MRI) features and feasibility of differentiating HCA subtypes…”
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Neratinib + fulvestrant + trastuzumab for HR-positive, HER2-negative, HER2-mutant metastatic breast cancer: outcomes and biomarker analysis from the SUMMIT trial by Jhaveri, K., Eli, L.D., Wildiers, H., Hurvitz, S.A., Guerrero-Zotano, A., Unni, N., Brufsky, A., Park, H., Waisman, J., Yang, E.S., Spanggaard, I., Reid, S., Burkard, M.E., Vinayak, S., Prat, A., Arnedos, M., Bidard, F.-C., Loi, S., Crown, J., Bhave, M., Piha-Paul, S.A., Suga, J.M., Chia, S., Saura, C., Garcia-Saenz, J.Á., Gambardella, V., de Miguel, M.J., Gal-Yam, E.N., Rapael, A., Stemmer, S.M., Ma, C., Hanker, A.B., Ye, D., Goldman, J.W., Bose, R., Peterson, L., Bell, J.S.K., Frazier, A., DiPrimeo, D., Wong, A., Arteaga, C.L., Solit, D.B.

“…HER2 mutations are targetable alterations in patients with hormone receptor-positive (HR+) metastatic breast cancer (MBC). In the SUMMIT basket study, patients…”
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SAR user guide to the rectal MR synoptic report (primary staging) by Kassam, Z., Lang, R., Bates, D. D. B., Chang, K. J., Fraum, T. J., Friedman, K. A., Golia Pernicka, J. S., Gollub, M. J., Harisinghani, M., Khatri, G., Lall, C., Lee, S., Magnetta, M., Nougaret, S., Paspulati, R. M., Paroder, V., Shaish, H., Kim, D. H.

“…Rectal MR is the key diagnostic exam at initial presentation for rectal cancer patients. It is the primary determinant in establishing clinical stage for the…”
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Necrotizing granulomatous epididymo-orchitis post intravesical BCG administration after brachytherapy for prostate cancer by Jhaveri, Jay K., Dahmen, Aaron, Lazarovich, Alon, Nusbaum, David, Trinh, Quoc-Dien, Gupta, Nilesh, Agarwal, Piyush K.

“…Urothelial carcinoma of the bladder remains a challenging disease to treat. Intravesical instillation of BCG has demonstrated tremendous efficacy in preventing…”
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Breast carcinoma with brain metastases: clinical analysis and immunoprofile on tissue microarrays by Brogi, E., Murphy, C.G., Johnson, M.L., Conlin, A.K., Hsu, M., Patil, S., Akram, M., Nehhozina, T., Jhaveri, K.L., Hudis, C.A., Seidman, A.D.

“…Development of brain metastasis in patients with breast carcinoma correlates with poor outcome. Identification of tumor characteristics associated with breast…”
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Complete remission of nephrotic syndrome and acute kidney injury in crescentic IgA nephropathy: Role of mycophenolate sodium by Bhandari, D, Jhaveri, K, Shah, H

“…Optimal therapy and prognosis of crescentic-IgA nephropathy (C-IgAN) are not known. Reported treatment options for C-IgAN include combination of…”
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Real-world treatment patterns and outcomes in patients with HR+/HER2− metastatic breast cancer treated with chemotherapy in the United States by Tolaney, S.M., Punie, K., Carey, L.A., Kurian, A.W., Ntalla, I., Sjekloca, N., Shah, A., Rehnquist, M.K., Stokes, M., Fraeman, K., Verret, W., Jhaveri, K.

“…Until recently, treatment options for patients with hormone receptor-positive/human epidermal growth factor 2-negative (HR+/HER2−) metastatic breast cancer…”
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Can contrast-enhanced MRI with gadoxetic acid predict liver failure and other complications after major hepatic resection? by Costa, A.F, Tremblay St-Germain, A, Abdolell, M, Smoot, R.L, Cleary, S, Jhaveri, K.S

“…Aim To determine whether a combination of clinical factors, the future liver remnant (FLR) ratio, and hepatic uptake of gadoxetic acid can be used to predict…”
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Correction: SAR user guide to the rectal MR synoptic report (primary staging) by Kassam, Z., Lang, R., Bates, D. D. B., Chang, K. J., Fraum, T. J., Friedman, K. A., Golia Pernicka, J. S., Gollub, M. J., Harisinghani, M., Khatri, G., Lall, C., Lee, S., Magnetta, M., Nougaret, S., Paspulati, R. M., Paroder, V., Shaish, H., Kim, D. H.

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The role of p21-activated kinase in the initiation of atherosclerosis by Jhaveri, K A, Debnath, P, Chernoff, J, Sanders, J, Schwartz, M A

“…p21-activated kinase (PAK) has been implicated in the inflammatory activation of endothelial cells by disturbed fluid shear stress, which is the initiating…”
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Does injection flow rate have an impact on arterial phase image degradation in liver MRI? A comparison of gadoxetic acid versus gadobutrol by Cohen-Hallaleh, V., Guo, L., Hosseini-Nik, H., Razaghi Kashani, N., Menezes, R., Jhaveri, K.

“…To evaluate retrospectively the impact of injection flow rate on arterial phase image degradation in liver magnetic resonance imaging (MRI) with gadoxetic acid…”
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Capivasertib and fulvestrant for patients with hormone receptor-positive advanced breast cancer: characterization, time course, and management of frequent adverse events from the phase III CAPItello-291 study by Rugo, H.S., Oliveira, M., Howell, S.J., Dalenc, F., Cortes, J., Gomez, H.L., Hu, X., Jhaveri, K.L., Krivorotko, P., Loibl, S., Morales Murillo, S., Nowecki, Z., Okera, M., Park, Y.H., Sohn, J., Toi, M., Iwata, H., Yousef, S., Zhukova, L., Logan, J., Twomey, K., Khatun, M., D’Cruz, C.M., Turner, N.C.

“…Capivasertib is a potent, selective pan-AKT inhibitor. In CAPItello-291, the addition of capivasertib to fulvestrant resulted in a statistically significant (P…”
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Abstract TF1-2: ER+ word salad decoded: SERD, SERM, SERCA, CERAN, PROTAC by Jhaveri, K

“…Estrogen receptor (ER) plays an important role in gene transcription and the proliferation of ER positive (ER+) breast cancers. Selective estrogen receptor…”
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Evaluation of two outreach tools, an educator program and a mobile tidepool exhibit, in reducing deleterious visitor activities and raising marine protected area awareness in rocky intertidal ecosystems of southern California, USA by Jhaveri, Parth K., Smith, Jayson R.

“…Rocky intertidal habitats in urbanized settings, such as in southern California, USA, are heavily perturbed by human visitors (tidepoolers) through the…”
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Effect of environmental temperature on sleep, locomotor activity, core body temperature and immune responses of C57BL/6J mice by Jhaveri, K.A, Trammell, R.A, Toth, L.A

“…Abstract Ambient temperature exerts a prominent influence on sleep. In rats and humans, low ambient temperatures generally impair sleep, whereas higher…”
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Intravenous albumin infusion is an effective therapy for hyponatremia in patient with malignant ascites by Jhaveri, K, Chawla, A, Xu, C, Hazzan, A

“…There are few reports about the treatment of moderate to severe hyponatremia associated with malignant liver metastasis. Here, we report using intravenous salt…”
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Elevated human chorionic gonadotropin levels in patients with chronic kidney disease: Case series and review of literature by Soni, S, Menon, M, Bhaskaran, M, Jhaveri, K, Molmenti, E, Muoio, V

“…Women are often subjected to serum human chorionic gonadotropin (HCG) testing prior to diagnostic and therapeutic interventions. A positive result leads to…”
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