Search Results - "Jha, Anupam Nath"

Leishmaniasis: Omics Approaches to Understand its Biology from Molecule to Cell Level by Kumari, Indu, Lakhanpal, Dinesh, Swargam, Sandeep, Nath Jha, Anupam

“…Leishmaniasis is the second deadliest vector-borne, neglected tropical zoonotic disease and is found in a variety of clinical forms based on genetic…”
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Deciphering the Interaction of 5,7‐Dihydroxyflavone with Hen‐Egg‐White Lysozyme through Multispectroscopic and Molecular Dynamics Simulation Approaches by Das, Sourav, Khanikar, Portia, Hazarika, Zaved, Rohman, Mostofa Ataur, Uzir, Antara, Nath Jha, Anupam, Singha Roy, Atanu

“…In recent times, research based on the bio‐active flavonoid, chrysin has shown its potential therapeutic applications such as anti‐diabetic, neuroprotective,…”
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Computational multi-target approach to target essential enzymes of Leishmania donovani using comparative molecular dynamic simulations and MMPBSA analysis by Saha, Debanjan, Nath Jha, Anupam

“…Visceral leishmaniasis (VL) is caused by Leishmania donovani. The purine and pyrimidine pathways are essential for L. donovani. Simultaneously inhibiting…”
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Editorial: Computational approaches to build therapeutic paradigms targeting genes, proteins and pathways against neglected tropical diseases (NTDs) by Jha, Anupam Nath

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Structural and functional premise of transport protein transthyretin in the sight of silver and zinc oxide nanoparticles through atomistic simulations by Hazarika, Zaved, Nath Jha, Anupam

“…[Display omitted] •Impact of inorganic nanoparticles on transthyretin and their fate on biological reactivity have been assessed.•The dynamic interaction of…”
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An integrative approach using systems biology, mutational analysis with molecular dynamics simulation to challenge the functionality of a target protein by Bora, Nikita, Nath Jha, Anupam

“…Visceral leishmaniasis affects millions of people worldwide in areas where Leishmania donovani is endemic. The protozoan species serves a greater threat as it…”
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Computational Analysis of the Silver Nanoparticle–Human Serum Albumin Complex by Hazarika, Zaved, Jha, Anupam Nath

“…Drug delivery in excess concentrations and at not-specified sites inside the human body adversely affects the body and gives rise to other diseases. Several…”
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In silico Metabolic Pathway Analysis Identifying Target Against Leishmaniasis - A Kinetic Modeling Approach by Bora, Nikita, Jha, Anupam Nath

“…The protozoan , from trypanosomatids family is a deadly human pathogen responsible for causing Visceral Leishmaniasis. Unavailability of proper treatment in…”
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Identification and analysis of structurally critical fragments in HopS2 by Borah, Sapna M, Jha, Anupam Nath

“…Among the diverse roles of the Type III secretion-system (T3SS), one of the notable functions is that it serves as unique nano machineries in gram-negative…”
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Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis by Kumari, Priya, Mamud, Afrin, Jha, Anupam Nath

“…Leishmaniasis is one of the Neglected Tropical Diseases (NTDs), a zoonotic disease of vector-borne nature that is caused by a protozoan parasite . This…”
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Amino acid interaction preferences in proteins by Nath Jha, Anupam, Vishveshwara, Saraswathi, Banavar, Jayanth R.

“…Understanding the key factors that influence the interaction preferences of amino acids in the folding of proteins have remained a challenge. Here we present a…”
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Deciphering antiviral efficacy of malaria box compounds against malaria exacerbating viral pathogens- Epstein Barr virus and SARS-CoV-2, an in silico study by Indari, Omkar, Kumar Singh, Ajit, Tiwari, Deeksha, Chandra Jha, Hem, Nath Jha, Anupam

“…In malaria endemic countries, coinfections and cotransmissions of different viral pathogens are widely reported. Prior studies have shown that malaria can…”
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Amino acid interaction preferences in helical membrane proteins by Nath Jha, Anupam, Vishveshwara, Saraswathi, Banavar, Jayanth R.

“…Membrane proteins are involved in a number of important biological functions. Yet, they are poorly understood from the structure and folding point of view. The…”
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A search for energy minimized sequences of proteins by Jha, Anupam Nath, Ananthasuresh, G K, Vishveshwara, Saraswathi

“…In this paper, we present numerical evidence that supports the notion of minimization in the sequence space of proteins for a target conformation. We use the…”
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Integrated subtractive genomics and structure-based approach to unravel the therapeutic drug target of Leishmania species by Saha, Debanjan, Jha, Anupam Nath

“…Leishmaniasis is a complex vector-borne disease caused by intracellular protozoan parasites of the Leishmania genus. It presents a significant public health…”
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In silico analysis of antiviral phytochemicals efficacy against Epstein-Barr virus glycoprotein H by Jakhmola, Shweta, Hazarika, Zaved, Jha, Anupam Nath, Jha, Hem Chandra

“…Epstein-Barr virus is a tumor-associated, enveloped virus with glycoprotein receptor gHgL on its surface. gH attaches to epithelial or B cells and mediates…”
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Quorum Quenching: A Drug Discovery Approach Against Pseudomonas aeruginosa by Rather, Muzamil Ahmad, Saha, Debanjan, Bhuyan, Shuvam, Jha, Anupam Nath, Mandal, Manabendra

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Lactoferrin adsorption onto silver nanoparticle interface: Implications of corona on protein conformation, nanoparticle cytotoxicity and the formulation adjuvanticity by Nayak, Parth Sarathi, Borah, Sapna M., Gogoi, Himanshu, Asthana, Shreyasi, Bhatnagar, Rakesh, Jha, Anupam Nath, Jha, Suman

“…•BLf adsorption as corona reduces the cytotoxic propensity of AgNP.•BLf adsorption onto AgNP interface is predominantly enthalpically driven.•BLf in corona…”
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A Comprehensive Review of Drug Repurposing Strategies against Known Drug Targets of COVID-19 by Khataniar, Ankita, Pathak, Upasana, Rajkhowa, Sanchaita, Jha, Anupam Nath

“…Drug repurposing is a more inexpensive and shorter approach than the traditional drug discovery and development process. The concept of identifying a potent…”
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Molecular scaffold recognition of drug molecules against essential genes of Leishmania donovani using biocomputing approach by Saha, Debanjan, Borah, Nayan Jyoti, Jha, Anupam Nath

“…•Essential genes (Pyridoxal kinase and sterol alpha-14 demethylase) are drug targets.•Discerned the atomistic interactions of small molecules with target…”
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