Search Results - "Jguirim, I"

Effect of a splice site mutation in LDLR gene and two variations in PCSK9 gene in Tunisian families with familial hypercholesterolaemia by Jelassi, A, Slimani, A, Jguirim, I, Najah, M, Maatouk, F, Varret, M, Slimane, M N

“…Autosomal dominant hypercholesterolaemia (ADH) is due to defects in the LDL receptor gene (LDLR), in the apolipoprotein B-100 gene (APOB) or in the proprotein…”
Get more information

Limited mutational heterogeneity in the LDLR gene in familial hypercholesterolemia in Tunisia by Jelassi, A, Jguirim, I, Najah, M, Abid, A.M, Boughamoura, L, Maatouk, F, Rouis, M, Boileau, C, Rabès, J.P, Slimane, M.N, Varret, M

“…Abstract Familial hypercholesterolemia (FH) is an autosomal dominant disease caused by mutations in the low-density lipoprotein receptor ( LDLR ),…”
Get full text

A novel splice site mutation of the LDL receptor gene in a Tunisian hypercholesterolemic family by Jelassi, A., Najah, M., Jguirim, I., Maatouk, F., Lestavel, S., Laroussi, O.S., Rouis, M., Boileau, C., Rabès, J.P., Varret, M., Slimane, M.N.

“…Familial hypercholesterolemia (FH) is an autosomal dominant inherited disease caused by mutations in either the low-density lipoprotein receptor, the…”
Get full text

Association between variants of lipoprotein lipase and coronary heart disease in a Tunisian population by Jelassi, A, Jguirim, I, Slimani, A, Najah, M, Hamda, K B, Addad, F, Hassine, M, Maatouk, F, Varret, M, Slimane, M N

“…Coronary artery disease (CAD) is a complex multifactorial disease due to the interaction of multiple genes variations and environmental factors. Genetic…”
Get full text

Familial hypercholesterolemia in Tunisia by Jelassi, A, Jguirim, I, Najah, M, Maatouk, F, Ben Hamda, K, Slimane, M N

“…Familial hypercholesterolemia or autosomal dominant hypercholesterolemia is characterized by raised serum LDL (low density lipoproteins)-cholesterol levels,…”
Get full text

Association entre des variations de la lipoprotéine lipase et la maladie coronarienne dans une population tunisienne by Jelassi, A., Jguirim, I., Slimani, A., Najah, M., Hamda, K.B., Addad, F., Hassine, M., Maatouk, F., Varret, M., Slimane, M.N.

“…Les variations du gène de la lipoprotéine lipase peuvent contribuer à l’athérosclérose et aux maladies coronariennes. Le but de ce travail est d’examiner les…”
Get full text

L’hypercholestérolémie familiale en Tunisie by Jelassi, A., Jguirim, I., Najah, M., Maatouk, F., Hamda, K. Ben, Slimane, M.N.

“…L’hypercholestérolémie familiale ou l’hypercholestérolémie autosomique dominante est une pathologie caractérisée par une augmentation exclusive des…”
Get full text

294T/C polymorphism in the PPAR-delta gene is associated with risk of coronary artery disease in normolipidemic Tunisians by Jguirim-Souissi, I, Jelassi, A, Hrira, Y, Najah, M, Slimani, A, Addad, F, Hassine, M, Hamda, K B, Maatouk, F, Rouis, M, Slimane, M N

“…Peroxisome proliferator-activated receptor delta (PPAR-delta) is a transcription factor implicated in metabolism and inflammation. The +294T/C polymorphism in…”
Get full text

A011 Matrix metalloproteinase-12 gene regulation by PPAR alpha agonist in human monocyte-derived macrophages by Jguirim-Souissi, I, Billiet, L, Cuaz-Perolin, C, Slimane, M.-N, Rouis, M

“…MMP-12, a macrophage-specific matrix metalloproteinase with large substrate specificity, has been reported to be highly expressed in mice, rabbits and human…”
Get full text

294T/C polymorphism in the PPAR- delta gene is associated with risk of coronary artery disease in normoiipidemic Tunisians by Jguirim-Souissi, I, Jelassi, A, Hrira, Y, Najah, M, Slimani, A, Addad, F, Hassine, M, Hamda, K B, Maatouk, F, Rouis, M, Slimane, M N

“…Peroxisome proliferator-activated receptor delta (PPAR- delta ) is a transcription factor implicated in metabolism and inflammation. The +294T/C polymorphism…”
Get full text