Search Results - "Jeynes, J Charles G"
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1
In vitro reconstitution of branching microtubule nucleation
Published in eLife (14-01-2020)“…Eukaryotic cell division requires the mitotic spindle, a microtubule (MT)-based structure which accurately aligns and segregates duplicated chromosomes. The…”
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2
The feasibility of using citizens to segment anatomy from medical images: Accuracy and motivation
Published in PloS one (10-10-2019)“…The development of automatic methods for segmenting anatomy from medical images is an important goal for many medical and healthcare research areas. Datasets…”
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Nanoscale Properties of Human Telomeres Measured with a Dual Purpose X‑ray Fluorescence and Super Resolution Microscopy Gold Nanoparticle Probe
Published in ACS nano (26-12-2017)“…Techniques to analyze human telomeres are imperative in studying the molecular mechanism of aging and related diseases. Two important aspects of telomeres are…”
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4
Measuring and modelling cell-to-cell variation in uptake of gold nanoparticles
Published in Analyst (London) (07-12-2013)“…The cell-to-cell variation of gold nanoparticle (GNP) uptake is important for therapeutic applications. We directly counted the GNPs in hundreds of individual…”
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5
Monte Carlo Simulations of Heat Deposition During Photothermal Skin Cancer Therapy Using Nanoparticles
Published in Biomolecules (Basel, Switzerland) (05-08-2019)“…Photothermal therapy using nanoparticles is a promising new approach for the treatment of cancer. The principle is to utilise plasmonic nanoparticle light…”
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Radiosensitization of glioblastoma cells using a histone deacetylase inhibitor (SAHA) comparing carbon ions with X-rays
Published in International journal of radiation biology (01-01-2015)“…Abstract Purpose: Prognosis for patients with glioblastoma (GBM) remains poor, and new treatments are needed. Here we used a combination of two novel treatment…”
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Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry
Published in Analyst (London) (21-02-2018)“…Recent work using micro-Fourier transform infrared (μFTIR) imaging has revealed that a lipid-rich layer surrounds many plaques in post-mortem Alzheimer's…”
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Natural Language Processing for Drug Discovery Knowledge Graphs: promises and pitfalls
Published 24-10-2023“…Methods Mol Biol . 2024:2716:223-240 Building and analysing knowledge graphs (KGs) to aid drug discovery is a topical area of research. A salient feature of…”
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Generation of Chemically Unmodified Pure Single-Walled Carbon Nanotubes by Solubilizing with RNA and Treatment with Ribonuclease A
Published in Advanced materials (Weinheim) (19-06-2006)“…RNA is used to purify carbon nanotubes (CNTs) in a simple, two‐step method that does not require a time‐intensive process or harsh chemical or physical…”
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