Search Results - "Jevtić, Predrag"

Nuclear Size Scaling during Xenopus Early Development Contributes to Midblastula Transition Timing by Jevtić, Predrag, Levy, Daniel L.

“…Early Xenopus laevis embryogenesis is a robust system for investigating mechanisms of developmental timing. After a series of rapid cell divisions with…”
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Sizing and shaping the nucleus: mechanisms and significance by Jevtić, Predrag, Edens, Lisa J, Vuković, Lidija D, Levy, Daniel L

“…Highlights • Mechanisms of nuclear size and shape regulation. • Cell cycle events that influence nuclear morphology. • Nuclear morphology, chromatin…”
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Both Nuclear Size and DNA Amount Contribute to Midblastula Transition Timing in Xenopus laevis by Jevtić, Predrag, Levy, Daniel L.

“…During early Xenopus laevis embryogenesis both nuclear and cell volumes decrease with the nuclear-to-cytoplasmic (N/C) volume ratio reaching a maximum at the…”
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Altering the levels of nuclear import factors in early Xenopus laevis embryos affects later development by Jevtić, Predrag, Mukherjee, Richik N, Chen, Pan, Levy, Daniel L

“…More than just a container for DNA, the nuclear envelope carries out a wide variety of critical and highly regulated cellular functions. One of these functions…”
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Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding by Vuković, Lidija D, Jevtić, Predrag, Zhang, Zhaojie, Stohr, Bradley A, Levy, Daniel L

“…Altered nuclear size is associated with many cancers, and determining whether cancer-associated changes in nuclear size contribute to carcinogenesis…”
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The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity by Jevtić, Predrag, Schibler, Andria C, Wesley, Chase C, Pegoraro, Gianluca, Misteli, Tom, Levy, Daniel L

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ELUCIDATING NUCLEAR SIZE CONTROL IN THE XENOPUS MODEL SYSTEM by Predrag, Jevtić, Daniel, Levy L

“…Nuclear size is a tightly regulated cellular feature. Mechanisms that regulate nuclear size and the functional significance of this regulation are largely…”
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Quality control of protein complex composition by Padovani, Chris, Jevtić, Predrag, Rapé, Michael

“…Eukaryotic cells possess hundreds of protein complexes that contain multiple subunits and must be formed at the correct time and place during development…”
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Identification of epigenetic modulators as determinants of nuclear size and shape by Schibler, Andria C, Jevtic, Predrag, Pegoraro, Gianluca, Levy, Daniel L, Misteli, Tom

“…The shape and size of the human cell nucleus is highly variable among cell types and tissues. Changes in nuclear morphology are associated with disease,…”
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The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity by Jevtić, Predrag, Schibler, Andria C, Wesley, Chase C, Pegoraro, Gianluca, Misteli, Tom, Levy, Daniel L

“…How intracellular organelles acquire their characteristic sizes is a fundamental question in cell biology. Given stereotypical changes in nuclear size in…”
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Structural basis for dimerization quality control by Mena, Elijah L., Jevtić, Predrag, Greber, Basil J., Gee, Christine L., Lew, Brandon G., Akopian, David, Nogales, Eva, Kuriyan, John, Rape, Michael

“…Most quality control pathways target misfolded proteins to prevent toxic aggregation and neurodegeneration 1 . Dimerization quality control further improves…”
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Concentration-dependent Effects of Nuclear Lamins on Nuclear Size in Xenopus and Mammalian Cells by Jevtić, Predrag, Edens, Lisa J., Li, Xiaoyang, Nguyen, Thang, Chen, Pan, Levy, Daniel L.

“…A fundamental question in cell biology concerns the regulation of organelle size. While nuclear size is exquisitely controlled in different cell types,…”
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More Cytoplasm, More Problems by Jevtić, Predrag, Levy, Daniel L.

“…In this issue of Developmental Cell, Kyogoku and Kitajima (2017) investigate the effect of cytoplasmic volume on the fidelity of chromosome segregation during…”
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In vivo mitotic spindle scaling can be modulated by changing the levels of a single protein: the microtubule polymerase XMAP215 by Milunovic-Jevtic, Ana, Jevtic, Predrag, Levy, Daniel L, Gatlin, J C

“…In many organisms, early embryonic development is characterized by a series of reductive cell divisions that result in rapid increases in cell number and…”
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Mechanisms of nuclear size regulation in model systems and cancer by Jevtić, Predrag, Levy, Daniel L

“…Changes in nuclear size have long been used by cytopathologists as an important parameter to diagnose, stage, and prognose many cancers. Mechanisms underlying…”
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Nuclear size regulation: from single cells to development and disease by Edens, Lisa J, White, Karen H, Jevtic, Predrag, Li, Xiaoyang, Levy, Daniel L

“…Cell size varies greatly among different cell types and organisms, especially during early development when cell division is rapid with little overall growth…”
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New Insights into Mechanisms and Functions of Nuclear Size Regulation by Vuković, Lidija D, Jevtić, Predrag, Edens, Lisa J, Levy, Daniel L

“…Nuclear size is generally maintained within a defined range in a given cell type. Changes in cell size that occur during cell growth, development, and…”
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An insect antifreeze protein from Anatolica polita enhances the cryoprotection of Xenopus laevis eggs and embryos by Jevtić, Predrag, Elliott, K Wade, Watkins, Shelby E, Sreter, Jonathan A, Jovic, Katarina, Lehner, Ian B, Baures, Paul W, Tsavalas, John G, Levy, Daniel L, Varga, Krisztina

“…Cryoprotection is of interest in many fields of research, necessitating a greater understanding of different cryoprotective agents. Antifreeze proteins have…”
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Nuclear size scaling during Xenopus early development contributes to the regulation of midblastula transition timing by Jevtić, Predrag, Levy, Daniel L.

“…Early Xenopus laevis embryogenesis is a robust system for investigating mechanisms of developmental timing. After a series of rapid cell divisions with…”
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Use of Xenopus cell-free extracts to study size regulation of subcellular structures by Jevtić, Predrag, Milunović-Jevtić, Ana, Dilsaver, Matthew R, Gatlin, Jesse C, Levy, Daniel L

“…Striking size variations are prominent throughout biology, at the organismal, cellular, and subcellular levels. Important fundamental questions concern…”
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