Search Results - "Jeurissen, Suzanne M. F."

Human Cytochrome P450 Enzymes of Importance for the Bioactivation of Methyleugenol to the Proximate Carcinogen 1‘-Hydroxymethyleugenol by Jeurissen, Suzanne M. F, Bogaards, Jan J. P, Boersma, Marelle G, ter Horst, Judith P. F, Awad, Hanem M, Fiamegos, Yiannis C, van Beek, Teris A, Alink, Gerrit M, Sudhölter, Ernst J. R, Cnubben, Nicole H. P, Rietjens, Ivonne M. C. M

“…In vitro studies were performed to elucidate the human cytochrome P450 enzymes involved in the bioactivation of methyleugenol to its proximate carcinogen…”
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Human Cytochrome P450 Enzyme Specificity for Bioactivation of Safrole to the Proximate Carcinogen 1‘-Hydroxysafrole by Jeurissen, Suzanne M. F, Bogaards, Jan J. P, Awad, Hanem M, Boersma, Marelle G, Brand, Walter, Fiamegos, Yiannis C, van Beek, Teris A, Alink, Gerrit M, Sudhölter, Ernst J. R, Cnubben, Nicole H. P, Rietjens, Ivonne M. C. M

“…In the present study, the cytochrome P450 mediated bioactivation of safrole to its proximate carcinogenic metabolite, 1‘-hydroxysafrole, has been investigated…”
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Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and biphenyls (PCBs) in home-produced eggs by Hoogenboom, Ron L.A.P., ten Dam, Guillaume, van Bruggen, Mark, Jeurissen, Suzanne M.F., van Leeuwen, Stefan P.J., Theelen, Rob M.C., Zeilmaker, Marco J.

“…Home produced eggs from 62 addresses in the Netherlands were investigated for the levels of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/Fs) and…”
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Dioxins, PCBs and heavy metals in Chinese mitten crabs from Dutch rivers and lakes by Hoogenboom, Ron L.A.P., Kotterman, Michiel J.J., Hoek-van Nieuwenhuizen, Marion, van der Lee, Martijn K., Mennes, Wim C., Jeurissen, Suzanne M.F., van Leeuwen, Stefan P.J.

“…[Display omitted] •Reported high dioxin and PCB levels in brown meat of mitten crab were confirmed.•White meat compliant with EU-limits, for brown meat no…”
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Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1′-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human hepatoma cells by Jeurissen, Suzanne M.F., Punt, Ans, Delatour, Thierry, Rietjens, Ivonne M.C.M.

“…The effects of a basil extract on the sulfation and concomitant DNA adduct formation of the proximate carcinogen 1′-hydroxyestragole were studied using rat and…”
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Human Cytochrome P450 Enzyme Specificity for the Bioactivation of Estragole and Related Alkenylbenzenes by Jeurissen, Suzanne M. F., Punt, Ans, Boersma, Marelle G., Bogaards, Jan J. P., Fiamegos, Yiannis C., Schilter, Benoit, van Bladeren, Peter J., Cnubben, Nicole H. P., Rietjens, Ivonne M. C. M.

“…Human cytochrome P450 enzymes involved in the bioactivation of estragole to its proximate carcinogen 1‘-hydroxyestragole were identified and compared to the…”
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Development of an on-line high performance liquid chromatography detection system for human cytochrome P450 1A2 inhibitors in extracts of natural products by Jeurissen, Suzanne M.F., Claassen, Frank W., Havlik, Jaroslav, Bouwmans, Evelien E., Cnubben, Nicole H.P., Sudhölter, Ernst J.R., Rietjens, Ivonne M.C.M., van Beek, Teris A.

“…An on-line HPLC screening method for detection of inhibitors of human cytochrome P450 1A2 in extracts was developed. HPLC separation of extracts is connected…”
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Recent developments in the rapid analysis of plants and tracking their bioactive constituents by Beek, T.A. van, Tetala, K.K.R, Koleva, I, Dapkevicius, A, Exarchou, V, Jeurissen, S.M.F, Claassen, F.W, Klift, E.J.C. van der

“…Natural products chemistry has witnessed many new developments in the last 5 years like extractions with subcritical water and ionic liquids, LC/HRMS and…”
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Flavonoids and alkenylbenzenes: mechanisms of mutagenic action and carcinogenic risk by Rietjens, Ivonne M C M, Boersma, Marelle G, van der Woude, Hester, Jeurissen, Suzanne M F, Schutte, Maaike E, Alink, Gerrit M

“…The present review focuses on the mechanisms of mutagenic action and the carcinogenic risk of two categories of botanical ingredients, namely the flavonoids…”
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