Search Results - "Jeurissen, S.M.F"

P19-55 Working towards the implementation of NAMs for regulatory use in risk assessment – considerations regarding quantitative in vitro to in vivo extrapolation by Zwartsen, A., Jeurissen, S.M.F., Wit-Bos, L. de, Bokkers, B.G.H.

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Indicators for early identification of re-emerging mycotoxins by van der Fels-Klerx, H.J., Dekkers, S., Kandhai, M.C., Jeurissen, S.M.F., Booij, C.J.H., de Heer, C.

“…The aim of this study was to select the most important indicators for early identification of re-emerging mycotoxins in wheat, maize, peanuts and tree nuts…”
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Dioxins, PCBs and heavy metals in Chinese mitten crabs from Dutch rivers and lakes by Hoogenboom, Ron L.A.P., Kotterman, Michiel J.J., Hoek-van Nieuwenhuizen, Marion, van der Lee, Martijn K., Mennes, Wim C., Jeurissen, Suzanne M.F., van Leeuwen, Stefan P.J.

“…[Display omitted] •Reported high dioxin and PCB levels in brown meat of mitten crab were confirmed.•White meat compliant with EU-limits, for brown meat no…”
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Septic Arthritis Caused by Legionella dumoffii in a Patient with Systemic Lupus Erythematosus-Like Disease by Flendrie, M, Jeurissen, M, Franssen, M, Kwa, D, Klaassen, C, Vos, F

“…We describe a patient with systemic lupus erythematosus (SLE)-like disease on immunosuppressive treatment who developed septic arthritis of the knee involving…”
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Pharmacologically effective red yeast rice preparations marketed as dietary supplements illustrated by a case report by Venhuis, B.J., van Hunsel, F., van de Koppel, S., Keizers, P.H.J., Jeurissen, S.M.F., De Kaste, D.

“…This paper reports a typical statin‐related adverse reaction from a red yeast rice (RYR) supplement and the analytical findings from the supplement. It also…”
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Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1′-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human hepatoma cells by Jeurissen, Suzanne M.F., Punt, Ans, Delatour, Thierry, Rietjens, Ivonne M.C.M.

“…The effects of a basil extract on the sulfation and concomitant DNA adduct formation of the proximate carcinogen 1′-hydroxyestragole were studied using rat and…”
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Human Cytochrome P450 Enzyme Specificity for the Bioactivation of Estragole and Related Alkenylbenzenes by Jeurissen, Suzanne M. F., Punt, Ans, Boersma, Marelle G., Bogaards, Jan J. P., Fiamegos, Yiannis C., Schilter, Benoit, van Bladeren, Peter J., Cnubben, Nicole H. P., Rietjens, Ivonne M. C. M.

“…Human cytochrome P450 enzymes involved in the bioactivation of estragole to its proximate carcinogen 1‘-hydroxyestragole were identified and compared to the…”
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Flavonoids and alkenylbenzenes: mechanisms of mutagenic action and carcinogenic risk by Rietjens, Ivonne M C M, Boersma, Marelle G, van der Woude, Hester, Jeurissen, Suzanne M F, Schutte, Maaike E, Alink, Gerrit M

“…The present review focuses on the mechanisms of mutagenic action and the carcinogenic risk of two categories of botanical ingredients, namely the flavonoids…”
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Evaluation of Human Interindividual Variation in Bioactivation of Estragole Using Physiologically Based Biokinetic Modeling by Punt, Ans, Jeurissen, Suzanne M., Boersma, Marelle G., Delatour, Thierry, Scholz, Gabriele, Schilter, Benoît, van Bladeren, Peter J., Rietjens, Ivonne M. C. M.

“…The present study investigates interindividual variation in liver levels of the proximate carcinogenic metabolite of estragole, 1′-hydroxyestragole, due to…”
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Recent developments in the rapid analysis of plants and tracking their bioactive constituents by Beek, T.A. van, Tetala, K.K.R, Koleva, I, Dapkevicius, A, Exarchou, V, Jeurissen, S.M.F, Claassen, F.W, Klift, E.J.C. van der

“…Natural products chemistry has witnessed many new developments in the last 5 years like extractions with subcritical water and ionic liquids, LC/HRMS and…”
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Human Cytochrome P450 Enzymes of Importance for the Bioactivation of Methyleugenol to the Proximate Carcinogen 1‘-Hydroxymethyleugenol by Jeurissen, Suzanne M. F, Bogaards, Jan J. P, Boersma, Marelle G, ter Horst, Judith P. F, Awad, Hanem M, Fiamegos, Yiannis C, van Beek, Teris A, Alink, Gerrit M, Sudhölter, Ernst J. R, Cnubben, Nicole H. P, Rietjens, Ivonne M. C. M

“…In vitro studies were performed to elucidate the human cytochrome P450 enzymes involved in the bioactivation of methyleugenol to its proximate carcinogen…”
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Development of an on-line high performance liquid chromatography detection system for human cytochrome P450 1A2 inhibitors in extracts of natural products by Jeurissen, Suzanne M.F., Claassen, Frank W., Havlik, Jaroslav, Bouwmans, Evelien E., Cnubben, Nicole H.P., Sudhölter, Ernst J.R., Rietjens, Ivonne M.C.M., van Beek, Teris A.

“…An on-line HPLC screening method for detection of inhibitors of human cytochrome P450 1A2 in extracts was developed. HPLC separation of extracts is connected…”
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Human Cytochrome P450 Enzyme Specificity for Bioactivation of Safrole to the Proximate Carcinogen 1‘-Hydroxysafrole by Jeurissen, Suzanne M. F, Bogaards, Jan J. P, Awad, Hanem M, Boersma, Marelle G, Brand, Walter, Fiamegos, Yiannis C, van Beek, Teris A, Alink, Gerrit M, Sudhölter, Ernst J. R, Cnubben, Nicole H. P, Rietjens, Ivonne M. C. M

“…In the present study, the cytochrome P450 mediated bioactivation of safrole to its proximate carcinogenic metabolite, 1‘-hydroxysafrole, has been investigated…”
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