Search Results - "Jetté, Alexandra"
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The polarity protein Yurt associates with the plasma membrane via basic and hydrophobic motifs embedded in its FERM domain
Published in Journal of cell science (15-05-2024)“…The subcellular distribution of the polarity protein Yrt is subjected to a spatio-temporal regulation in D. melanogaster embryonic epithelia. After…”
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A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis
Published in PLoS genetics (01-10-2015)“…The co-chaperone BAG3, in complex with the heat shock protein HSPB8, plays a role in protein quality control during mechanical strain. It is part of a…”
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Girdin is a component of the lateral polarity protein network restricting cell dissemination
Published in PLoS genetics (20-03-2020)“…Epithelial cell polarity defects support cancer progression. It is thus crucial to decipher the functional interactions within the polarity protein network…”
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A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton downstream of Src family kinases
Published in The Journal of biological chemistry (24-01-2014)“…It is believed that mitochondrial dynamics is coordinated with endosomal traffic rates during cytoskeletal remodeling, but the mechanisms involved are largely…”
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Oligomerization of the FERM-FA protein Yurt controls epithelial cell polarity
Published in The Journal of cell biology (05-11-2018)“…Yurt (Yrt) and its mammalian orthologue EPB41L5 limit apical membrane growth in polarized epithelia. EPB41L5 also supports epithelial-mesenchymal transition…”
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Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex
Published in eLife (02-07-2021)“…The Drosophila polarity protein Crumbs is essential for the establishment and growth of the apical domain in epithelial cells. The protein Yurt limits the…”
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A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis: e1005582
Published in PLoS genetics (01-10-2015)“…The co-chaperone BAG3, in complex with the heat shock protein HSPB8, plays a role in protein quality control during mechanical strain. It is part of a…”
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Journal Article -
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A Functional Interplay between the Small GTPase Rab11a and Mitochondria-shaping Proteins Regulates Mitochondrial Positioning and Polarization of the Actin Cytoskeleton Downstream of Src Family KinasesThis work was supported in part by Canadian Institutes of Health Research Operating Grant MOP-49450 (to J. N. L.) and by the Natural Sciences and Engineering Research Council Grant RF:RGPIN371663 (to J. N. L.).▪▪This article contains supplemental Movie
Published in The Journal of biological chemistry (24-01-2014)“…It is believed that mitochondrial dynamics is coordinated with endosomal traffic rates during cytoskeletal remodeling, but the mechanisms involved are largely…”
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Journal Article