Search Results - "Jessup, M J"

The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-β signaling by Lin, L, Amin, R, Gallicano, G I, Glasgow, E, Jogunoori, W, Jessup, J M, Zasloff, M, Marshall, J L, Shetty, K, Johnson, L, Mishra, L, He, A R

“…Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide, with few effective therapeutic options for advanced disease. At least 40%…”
Get full text

Structural Controls on Crustal Fluid Circulation and Hot Spring Geochemistry Above a Flat‐Slab Subduction Zone, Peru by B. E. Scott, D. L. Newell, M. J. Jessup, T. A. Grambling, C. A. Shaw

“…Abstract Hot spring geochemistry from the Cordillera Blanca and Cordillera Huayhuash, Peru, reveal the influence of crustal‐scale structures on geothermal…”
Get full text

Timing of metamorphism, melting and exhumation of the Leo Pargil dome, northwest India by LANGILLE, J. M., JESSUP, M. J., COTTLE, J. M., LEDERER, G., AHMAD, T.

“…The Leo Pargil dome, northwest India, is a 30 km‐wide, northeast‐trending structure that is cored by gneiss and mantled by amphibolite facies metamorphic rocks…”
Get full text

Crustal thickening, Barrovian metamorphism, and exhumation of midcrustal rocks during doming and extrusion: Insights from the Himalaya, NW India by Jessup, M. J., Langille, J. M., Cottle, J. M., Ahmad, T.

“…Rocks exposed in NW India constrain the burial, partial melting, and exhumation history of the Himalayan crust. New microscale and mesoscale structural…”
Get full text

Kinematic and thermal studies of the Leo Pargil Dome: Implications for synconvergent extension in the NW Indian Himalaya by Langille, J. M., Jessup, M. J., Cottle, J., Ahmad, T.

“…Building of the Himalaya and Tibetan Plateau involved an interplay between crustal thickening and extension. The NW Indian Himalaya near the Leo Pargil dome…”
Get full text

2000 Update of Recommendations for the Use of Tumor Markers in Breast and Colorectal Cancer: Clinical Practice Guidelines of the American Society of Clinical Oncology by BAST, Robert C, RAVDIN, Peter, HAYES, Daniel F, BATES, Susan, FRITSCHE, Herbert JR, JESSUP, John M, KEMENY, Nancy, LOCKER, Gershon Y, MENNEL, Robert G, SOMMERFIELD, Mark R

“…To update the 1997 clinical practice guidelines for the use of tumor marker tests in the prevention, screening, treatment, and surveillance of breast and…”
Get full text

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines by KANE, M. F, LODA, M, GAIDA, G. M, LIPMAN, J, MISHRA, R, GOLDMAN, H, JESSUP, J. M, KOLODNER, R

“…Somatic mutations in DNA mismatch repair genes have been observed in sporadic tumors as well as cell lines and xenografts derived from such tumors implicating…”
Get full text

Surgical margin in hepatic resection for colorectal metastasis : A critical and improvable determinant of outcome by CADY, B, JENKINS, R. L, LAVIN, P, LINEHAN, D. C, STEELE, G. D, LEWIS, W. D, STONE, M. D, MCDERMOTT, W. V, JESSUP, J. M, BOTHE, A, LALOR, P, LOVETT, E. J

“…To update the analysis of technical and biologic factors related to hepatic resection for colorectal metastasis in a large single-institution series to…”
Get full text

NANOG modulates stemness in human colorectal cancer by Zhang, J, Espinoza, L A, Kinders, R J, Lawrence, S M, Pfister, T D, Zhou, M, Veenstra, T D, Thorgeirsson, S S, Jessup, J M

“…NANOG is a stem cell transcription factor that is essential for embryonic development, reprogramming normal adult cells and malignant transformation and…”
Get full text

Metamorphic history of the South Tibetan Detachment System, Mt. Everest region, revealed by RSCM thermometry and phase equilibria modelling by COTTLE, J. M., WATERS, D. J., RILEY, D., BEYSSAC, O., JESSUP, M. J.

“…This study combines microstructural observations with Raman spectroscopy on carbonaceous material (RSCM), phase equilibria modelling and U–Pb dating of…”
Get full text

The DCC Protein and Prognosis in Colorectal Cancer by Shibata, David, Reale, Michael A, Lavin, Philip, Silverman, Mark, Fearon, Eric R, Steele, Glenn, Jessup, John M, Loda, Massimo, Summerhayes, Ian C

“…Stage II or Dukes' stage B2 colorectal cancer accounts for approximately one third of the cases of colorectal cancer diagnosed annually in the United States…”
Get full text

Tumor Marker Utility Grading System: a Framework to Evaluate Clinical Utility of Tumor Markers by Hayes, Daniel F., Bast, Robert C., Desch, Christopher E., Fritsche, Herbert, Kemeny, Nancy E., Jessup, J. Milburn, Locker, Gershon Y., Macdonald, John S., Mennel, Robert G., Norton, Larry, Ravdin, Peter, Taube, Sheila, Winn, Rodger J.

“…Introduction of tumor markers into routine clinical practice has been poorly controlled, with few criteria or guidelines as to how such markers should be used…”
Get full text

The National Cancer Data Base report on colon cancer by Jessup, J. Milburn, McGinnis, Lamar S., Steele, Glenn D., Menck, Herman R., Winchester, David P.

“…Commission on Cancer data from the National Cancer Data Base (NCDB) report time trends in stage of disease, treatment patterns, and survival for patients with…”
Get full text

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis by BAKER, S. J, PREISINGER, A. C, JESSUP, J. M, PARASKEVA, C, MARKOWITZ, S, WILSON, J. K. V, HAMILTON, S, VOGELSTEIN, B

“…Coordinate loss of one copy of the p53 gene and mutation of the remaining copy occur in colorectal carcinomas and in many other human malignancies. However,…”
Get full text

Prospective evaluation of local excision for small rectal cancers by Bleday, R, Breen, E, Jessup, J M, Burgess, A, Sentovich, S M, Steele, Jr, G

“…Most data on local excisions for rectal cancer are based on retrospective studies. We review the results of a prospective registry of patients eligible for…”
Get more information

Reactive nitrogen and oxygen radicals formed during hepatic ischemia-reperfusion kill weakly metastatic colorectal cancer cells by JESSUP, J. M, BATTLE, P, WALLER, H, EDMISTON, K. H, STOLZ, D. B, WATKINS, S. C, LOCKER, J, SKENA, K

“…Microscopic infarcts develop within the livers of athymic nude mice during the first 24 h after human colorectal carcinoma (CRC) cells arrest within hepatic…”
Get full text

P-T-t-D paths of Everest Series schist, Nepal by JESSUP, M. J., COTTLE, J. M., SEARLE, M. P., LAW, R. D., NEWELL, D. L., TRACY, R. J., WATERS, D. J.

“…U(–Th)–Pb geochronology, geothermobarometric estimates and macro‐ and micro‐structural analysis, quantify the pressure–temperature–time–deformation (P–T–t–D)…”
Get full text

Prospects for use of microgravity-based bioreactors to study three-dimensional host-tumor interactions in human neoplasia by Jessup, J M, Goodwin, T J, Spaulding, G

“…Microgravity offers unique advantages for the cultivation of mammalian tissues because the lack of gravity-induced sedimentation supports three-dimensional…”
Get more information

Cathepsin B and other proteases in human colorectal carcinoma by JESSUP, J. M

Get full text

Chemoradiotherapy after Surgery Compared with Surgery Alone for Adenocarcinoma of the Stomach or Gastroesophageal Junction by Macdonald, John S, Smalley, Stephen R, Benedetti, Jacqueline, Hundahl, Scott A, Estes, Norman C, Stemmermann, Grant N, Haller, Daniel G, Ajani, Jaffer A, Gunderson, Leonard L, Jessup, J. Milburn, Martenson, James A

“…This large trial shows that postoperative chemoradiotherapy can increase survival after gastric resection. The curative treatment of stomach cancer requires…”
Get full text