Search Results - "Jessup, J. Milburn"

American Society of Clinical Oncology Provisional Clinical Opinion: Testing for KRAS Gene Mutations in Patients With Metastatic Colorectal Carcinoma to Predict Response to Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Therapy by ALLEGROA, Carmen J, MILBURN JESSUP, J, SOMERFIELD, Mark R, HAMILTON, Stanley R, HAMMOND, Elizabeth H, HAYES, Daniel F, MCALLISTER, Pamela K, MORTON, Roscoe F, SCHILSKY, Richard L

“…An American Society of Clinical Oncology (ASCO) provisional clinical opinion (PCO), offers timely clinical direction to ASCO's oncologists following…”
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Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study by Dienstmann, R., Mason, M.J., Sinicrope, F.A., Phipps, A.I., Tejpar, S., Nesbakken, A., Danielsen, S.A., Sveen, A., Buchanan, D.D., Clendenning, M., Rosty, C., Bot, B., Alberts, S.R., Milburn Jessup, J., Lothe, R.A., Delorenzi, M., Newcomb, P.A., Sargent, D., Guinney, J.

“…TNM staging alone does not accurately predict outcome in colon cancer (CC) patients who may be eligible for adjuvant chemotherapy. It is unknown to what extent…”
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Updated Analysis of SWOG-Directed Intergroup Study 0116: A Phase III Trial of Adjuvant Radiochemotherapy Versus Observation After Curative Gastric Cancer Resection by SMALLEY, Stephen R, BENEDETTI, Jacqueline K, STEMMERMANN, Grant N, BLANKE, Charles D, MACDONALD, John S, HALLER, Daniel G, HUNDAHL, Scott A, ESTES, Norman C, AJANI, Jaffer A, GUNDERSON, Leonard L, GOLDMAN, Bryan, MARTENSON, James A, JESSUP, J. Milburn

“…Surgical resection of gastric cancer has produced suboptimal survival despite multiple randomized trials that used postoperative chemotherapy or more…”
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Repurposing of mTOR Complex Inhibitors Attenuates MCL-1 and Sensitizes to PARP Inhibition by Mattoo, Abid R, Joun, Alex, Jessup, J Milburn

“…MCL-1, a member of the antiapoptotic BCL-2 family, is a prosurvival protein with an essential DNA repair function. This study aims to test whether inhibition…”
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Adjuvant Chemotherapy for Stage III Colon Cancer: Implications of Race/Ethnicity, Age, and Differentiation by Jessup, J. Milburn, Stewart, Andrew, Greene, Frederick L, Minsky, Bruce D

“…CONTEXT A 1990 National Institutes of Health Consensus Conference recommended that patients with stage III colon cancer receive adjuvant chemotherapy because…”
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The Role of Minimal Residual Disease Testing in Myeloma Treatment Selection and Drug Development: Current Value and Future Applications by Anderson, Kenneth C, Auclair, Daniel, Kelloff, Gary J, Sigman, Caroline C, Avet-Loiseau, Hervé, Farrell, Ann T, Gormley, Nicole J, Kumar, Shaji K, Landgren, Ola, Munshi, Nikhil C, Cavo, Michele, Davies, Faith E, Di Bacco, Alessandra, Dickey, Jennifer S, Gutman, Steven I, Higley, Howard R, Hussein, Mohamad A, Jessup, J Milburn, Kirsch, Ilan R, Little, Richard F, Loberg, Robert D, Lohr, Jens G, Mukundan, Lata, Omel, James L, Pugh, Trevor J, Reaman, Gregory H, Robbins, Michael D, Sasser, A Kate, Valente, Nancy, Zamagni, Elena

“…Treatment of myeloma has benefited from the introduction of more effective and better tolerated agents, improvements in supportive care, better understanding…”
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Population-Based Lynch Syndrome Screening by Microsatellite Instability in Patients ≤50: Prevalence, Testing Determinants, and Result Availability Prior to Colon Surgery by Karlitz, Jordan J, Hsieh, Mei-Chin, Liu, Yong, Blanton, Christine, Schmidt, Beth, Jessup, J Milburn, Wu, Xiao-Cheng, Chen, Vivien W

“…As there are no US population-based studies examining Lynch syndrome (LS) screening frequency by microsatellite instability (MSI) and immunohistochemistry…”
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Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents by Dancey, Janet E, Dobbin, Kevin K, Groshen, Susan, Jessup, J Milburn, Hruszkewycz, Andrew H, Koehler, Maria, Parchment, Ralph, Ratain, Mark J, Shankar, Lalitha K, Stadler, Walter M, True, Lawrence D, Gravell, Amy, Grever, Michael R

“…The National Cancer Institute (NCI) Investigational Drug Steering Committee (IDSC) charged the Biomarker Task Force to develop recommendations to improve the…”
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Analysis of stage and clinical/prognostic factors for colon and rectal cancer from SEER registries: AJCC and collaborative stage data collection system by Chen, Vivien W., Hsieh, Mei‐Chin, Charlton, Mary E., Ruiz, Bernardo A., Karlitz, Jordan, Altekruse, Sean F., Ries, Lynn A. G., Jessup, J. Milburn

“…BACKGROUND The Collaborative Stage (CS) Data Collection System enables multiple cancer registration programs to document anatomic and molecular pathology…”
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Leveling the Playing Field: Bringing Development of Biomarkers and Molecular Diagnostics up to the Standards for Drug Development by POSTE, George, CARBONE, David P, PARKINSON, David R, VERWEIJ, Jaap, HEWITT, Stephen M, MILBURN JESSUP, J

“…Molecular diagnostics are becoming increasingly important in clinical research to stratify or identify molecularly profiled patient cohorts for targeted…”
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Chemoradiotherapy after Surgery Compared with Surgery Alone for Adenocarcinoma of the Stomach or Gastroesophageal Junction by Macdonald, John S, Smalley, Stephen R, Benedetti, Jacqueline, Hundahl, Scott A, Estes, Norman C, Stemmermann, Grant N, Haller, Daniel G, Ajani, Jaffer A, Gunderson, Leonard L, Jessup, J. Milburn, Martenson, James A

“…This large trial shows that postoperative chemoradiotherapy can increase survival after gastric resection. The curative treatment of stomach cancer requires…”
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A QA Program for MRD Testing Demonstrates That Systematic Education Can Reduce Discordance Among Experienced Interpreters by Keeney, Michael, Wood, Brent L., Hedley, Benjamin D., DiGiuseppe, Joseph A., Stetler‐Stevenson, Maryalice, Paietta, Elisabeth, Lozanski, Gerard, Seegmiller, Adam C., Greig, Bruce W., Shaver, Aaron C., Mukundan, Lata, Higley, Howard R., Sigman, Caroline C., Kelloff, Gary, Jessup, J. Milburn, Borowitz, Michael J.

“…Background Minimal residual disease (MRD) in B lymphoblastic leukemia (B‐ALL) by flow cytometry is an established prognostic factor used to adjust treatment in…”
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Bridging the Gap: Moving Predictive and Prognostic Assays from Research to Clinical Use by MICHAEL WILLIAMS, P, LIVELY, Tracy G, MILBURN JESSUP, J, CONLEY, Barbara A

“…The development of clinically useful molecular diagnostics requires validation of clinical assay performance and achievement of clinical qualification in…”
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Adenovirus and Oxaliplatin cooperate as agnostic sensitizers for immunogenic cell death in colorectal carcinoma by Jessup, J. Milburn, Kabbout, Mohamed, Korokhov, Nikolay, Joun, Alex, Tollefson, Ann E., Wold, William S. M., Mattoo, Abid R.

“…Treatments with cytotoxic agents or viruses may cause Immunogenic Cell Death (ICD) that immunize tumor-bearing hosts but do not cause complete regression of…”
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Lessons Learned from the Investigational Device Exemption Review of Children's Oncology Group Trial AAML1031 by MESHINCHI, Soheil, HUNGER, Stephen P, APLENC, Richard, ADAMSON, Peter C, MILBURN JESSUP, J

“…The U.S. Food and Drug Administration is now exerting its regulatory authority over the use of molecular diagnostics and related assays for medical decision…”
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Saturation diving alters folate status and biomarkers of DNA damage and repair by Zwart, Sara R, Jessup, J Milburn, Ji, Jiuping, Smith, Scott M

“…Exposure to oxygen-rich environments can lead to oxidative damage, increased body iron stores, and changes in status of some vitamins, including folate…”
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DR5 Receptor Mediates Anoikis in Human Colorectal Carcinoma Cell Lines by LAGUINGE, Luciana M, SAMARA, Raed N, WENGE WANG, EL-DEIRY, Wafik S, CORNER, Georgia, AUGENLICHT, Leonard, MISHRA, Lopa, MILBURN JESSUP, J

“…As human colorectal cancer (CRC) cells metastasize to distant sites, they are susceptible to detachment-induced cell death or anoikis - a form of apoptosis…”
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Association of Minimal Residual Disease With Clinical Outcome in Pediatric and Adult Acute Lymphoblastic Leukemia: A Meta-analysis by Berry, Donald A, Zhou, Shouhao, Higley, Howard, Mukundan, Lata, Fu, Shuangshuang, Reaman, Gregory H, Wood, Brent L, Kelloff, Gary J, Jessup, J Milburn, Radich, Jerald P

“…Minimal residual disease (MRD) refers to the presence of disease in cases deemed to be in complete remission by conventional pathologic analysis. Assessing the…”
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'Evidence-based medicine: the time has come to set standards for staging'. Is a radical overhaul really needed? by Sobin, Leslie H, Compton, Carolyn A, Gospodarowicz, Mary, Greene, Frederick L, Gunderson, Leonard L, Jessup, J Milburn, Wittekind, Christian

“…This Invited Response addresses concerns and opinions expressed in an Invited Commentary, ‘Evidence‐based medicine: the time has come to set standards for…”
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Evidence of clinical utility: an unmet need in molecular diagnostics for patients with cancer by Parkinson, David R, McCormack, Robert T, Keating, Susan M, Gutman, Steven I, Hamilton, Stanley R, Mansfield, Elizabeth A, Piper, Margaret A, Deverka, Patricia, Frueh, Felix W, Jessup, J Milburn, McShane, Lisa M, Tunis, Sean R, Sigman, Caroline C, Kelloff, Gary J

“…This article defines and describes best practices for the academic and business community to generate evidence of clinical utility for cancer molecular…”
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