Search Results - "Jerry A. Nick"
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Safety and Effectiveness of Clofazimine for Primary and Refractory Nontuberculous Mycobacterial Infection
Published in Chest (01-10-2017)“…Clofazimine is an antimicrobial agent that has activity in vitro against mycobacteria. Increasingly, it has been used for the treatment of nontuberculous…”
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Investigating Nontuberculous Mycobacteria Transmission at the Colorado Adult Cystic Fibrosis Program
Published in American journal of respiratory and critical care medicine (01-05-2022)“…Healthcare-associated transmission of nontuberculous mycobacteria (NTM) among people with cystic fibrosis (pwCF) has been investigated at CF centers worldwide,…”
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3
Population Genomics and Inference of Mycobacterium avium Complex Clusters in Cystic Fibrosis Care Centers, United States
Published in Emerging infectious diseases (01-11-2021)“…Mycobacterium avium complex (MAC) species constitute most mycobacteria infections in persons with cystic fibrosis (CF) in the United States, but little is…”
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Nontuberculous Mycobacterial Infections in Cystic Fibrosis
Published in Thoracic surgery clinics (01-02-2019)“…Nontuberculous mycobacteria (NTM) are important emerging cystic fibrosis (CF) pathogens, with estimates of prevalence ranging from 6% to 13%. Diagnosis of NTM…”
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5
Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR
Published in PloS one (01-09-2011)“…The inability of neutrophils to eradicate Pseudomonas aeruginosa within the cystic fibrosis (CF) airway eventually results in chronic infection by the bacteria…”
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6
Nontuberculous Mycobacterial Infections in Cystic Fibrosis
Published in Clinics in chest medicine (01-03-2016)“…Nontuberculous mycobacteria (NTM) are important emerging cystic fibrosis (CF) pathogens, with estimates of prevalence ranging from 6% to 13%. Diagnosis of NTM…”
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7
Diagnosis of Cystic Fibrosis in Nonscreened Populations
Published in The Journal of pediatrics (01-02-2017)“…Objective Although the majority of cases of cystic fibrosis (CF) are now diagnosed through newborn screening, there is still a need to standardize the…”
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Dectin-1-Independent Macrophage Phagocytosis of Mycobacterium abscessus
Published in International journal of molecular sciences (04-07-2023)“…, a species of nontuberculous mycobacteria (NTM), is an opportunistic pathogen that is readily cleared by healthy lungs but can cause pulmonary infections in…”
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Healthcare-associated links in transmission of nontuberculous mycobacteria among people with cystic fibrosis (HALT NTM) study: Rationale and study design
Published in PloS one (20-12-2021)“…Healthcare-associated transmission of nontuberculous mycobacteria (NTM) among people with cystic fibrosis (pwCF) has been reported and is of increasing…”
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10
Genomic characterization of sporadic isolates of the dominant clone of Mycobacterium abscessus subspecies massiliense
Published in Scientific reports (28-07-2021)“…Recent studies have characterized a dominant clone (Clone 1) of Mycobacterium abscessus subspecies massiliense ( M. massiliense ) associated with high…”
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11
Neutrophil killing of Mycobacterium abscessus by intra- and extracellular mechanisms
Published in PloS one (19-04-2018)“…Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, are increasingly present in soft tissue infections and chronic lung diseases,…”
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12
Selective Metabolism of Hypothiocyanous Acid by Mammalian Thioredoxin Reductase Promotes Lung Innate Immunity and Antioxidant Defense
Published in The Journal of biological chemistry (21-06-2013)“…The endogenously produced oxidant hypothiocyanous acid (HOSCN) inhibits and kills pathogens but paradoxically is well tolerated by mammalian host tissue…”
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13
Nontuberculous Mycobacterial Infections in Cystic Fibrosis
Published in Clinics in chest medicine (01-03-2015)“…Nontuberculous mycobacteria (NTM) are important emerging cystic fibrosis (CF) pathogens. Factors including the steady aging of the CF population, the apparent…”
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14
Population Genomics of Mycobacterium abscessus from U.S. Cystic Fibrosis Care Centers
Published in Annals of the American Thoracic Society (01-12-2021)“…is a significant threat to individuals with cystic fibrosis (CF) because of innate drug resistance and potential transmission between patients. Recent studies…”
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15
Unique Features of Mycobacterium abscessus Biofilms Formed in Synthetic Cystic Fibrosis Medium
Published in Frontiers in microbiology (29-10-2021)“…Characterizing Mycobacterium abscessus complex (MABSC) biofilms under host-relevant conditions is essential to the design of informed therapeutic strategies…”
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16
Mycobacterium abscessus morphotype comparison in a murine model
Published in PloS one (12-02-2015)“…Pulmonary infections with Mycobacterium abscessus (M. abscessus) are increasingly prevalent in patients with lung diseases such as cystic fibrosis. M…”
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Blood mRNA biomarkers distinguish variable systemic and sputum inflammation at treatment initiation of inhaled antibiotics in cystic fibrosis: A prospective non-randomized trial
Published in PloS one (05-05-2022)“…Inhaled antibiotics control chronic airway infection and maintain respiratory health in cystic fibrosis (CF). Given variation in patient responses to inhaled…”
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Corticosteroid use and increased CXCR2 levels on leukocytes are associated with lumacaftor/ivacaftor discontinuation in cystic fibrosis patients homozygous for the F508del CFTR mutation
Published in PloS one (12-12-2018)“…Cystic fibrosis (CF) is the most common life-shortening genetic disease and is caused by mutations in the cystic fibrosis transmembrane conductance regulator…”
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19
Headspace Solid-Phase Micro-Extraction Method Optimization and Evaluation for the Volatile Compound Extraction of Bronchoalveolar Lung Lavage Fluid Samples
Published in Separations (01-01-2024)“…Headspace solid-phase micro-extraction (HS-SPME) is a prevalent technique in metabolomics and volatolomics research. However, the performance of HS-SPME can…”
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Deficient Complement Opsonization Impairs Mycobacterium avium Killing by Neutrophils in Cystic Fibrosis
Published in Microbiology spectrum (14-02-2023)“…Nontuberculous mycobacteria (NTM), including Mycobacterium avium, are clinically important pathogens in cystic fibrosis (CF). The innate immune response to M…”
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