Search Results - "Jeroen de Jonge"

GABAergic Mechanisms in Schizophrenia: Linking Postmortem and In Vivo Studies by de Jonge, Jeroen C, Vinkers, Christiaan H, Hulshoff Pol, Hilleke E, Marsman, Anouk

“…Schizophrenia is a psychiatric disorder characterized by hallucinations, delusions, disorganized thinking, and impairments in cognitive functioning. Evidence…”
Get full text

Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish by Willemse, Jorke, Roos, Floris J. M., Voogt, Iris J., Schurink, Ivo J., Bijvelds, Marcel, Jonge, Hugo R., Laan, Luc J. W., Jonge, Jeroen, Verstegen, Monique M. A.

“…Biliary disorders can lead to life‐threatening disease and are also a challenging complication of liver transplantation. As there are limited treatment…”
Get full text

Evaluation of the New American Joint Committee on Cancer Staging Manual 8th Edition for Perihilar Cholangiocarcinoma by Gaspersz, Marcia P., Buettner, Stefan, van Vugt, Jeroen L. A., de Jonge, Jeroen, Polak, Wojciech G., Doukas, Michail, Ijzermans, Jan N. M., Koerkamp, Bas Groot, Willemssen, François E. J. A.

“…Background The aim was to compare the prognostic accuracy of cross-sectional imaging of the 7th and 8th editions of the American Joint Committee on…”
Get full text

Hypo- and normothermic perfusion of the liver: Which way to go? by Selten, Jasmijn, MD, Schlegel, Andrea, de Jonge, Jeroen, MD, PhD, Dutkowski, Philipp, MD, PhD

“…Abstract The demand of donor livers for transplantation exceeds the supply. In an attempt to maximize the number of potentially usable donor livers, several…”
Get full text

A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion by Schurink, Ivo J., de Haan, Jubi E., Willemse, Jorke, Mueller, Matteo, Doukas, Michael, Roest, Henk, de Goeij, Femke H. C., Polak, Wojciech G., Ijzermans, Jan N. M., Dutkowski, Philipp, van der Laan, Luc J. W., de Jonge, Jeroen

“…No single reliable parameter exists to assess liver graft function of extended criteria donors during ex-vivo normothermic machine perfusion (NMP). The liver…”
Get full text

Outcome of Esophagectomy for Cancer in Elderly Patients by Cijs, Tanja M., MD, Verhoef, Cees, MD, PhD, Steyerberg, Ewout W., PhD, Koppert, Linetta B., MD, PhD, Tran, T.C. Khe, MD, Wijnhoven, Bas P.L., MD, PhD, Tilanus, Hugo W., MD, PhD, de Jonge, Jeroen, MD, PhD

“…Background This study analyzes the outcome of esophageal resection in patients 70 or more years of age, compared with patients aged less than 70 years and…”
Get full text

PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke-statistical analysis plan of a randomised, open, phase III, clinical trial with blinded outcome assessment by de Jonge, Jeroen C, Woodhouse, Lisa J, Reinink, Hendrik, van der Worp, H Bart, Bath, Philip M

“…Aspiration, infections, and fever are common in the first days after stroke, especially in older patients. The occurrence of these complications has been…”
Get full text

Precancerous liver diseases do not cause increased mutagenesis in liver stem cells by Nguyen, Luan, Jager, Myrthe, Lieshout, Ruby, de Ruiter, Petra E., Locati, Mauro D., Besselink, Nicolle, van der Roest, Bastiaan, Janssen, Roel, Boymans, Sander, de Jonge, Jeroen, IJzermans, Jan N. M., Doukas, Michail, Verstegen, Monique M. A., van Boxtel, Ruben, van der Laan, Luc J. W., Cuppen, Edwin, Kuijk, Ewart

“…Inflammatory liver disease increases the risk of developing primary liver cancer. The mechanism through which liver disease induces tumorigenesis remains…”
Get full text

Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial by van Rijn, Rianne, Schurink, Ivo J, de Vries, Yvonne, van den Berg, Aad P, Cortes Cerisuelo, Miriam, Darwish Murad, Sarwa, Erdmann, Joris I, Gilbo, Nicholas, de Haas, Robbert J, Heaton, Nigel, van Hoek, Bart, Huurman, Volkert A.L, Jochmans, Ina, van Leeuwen, Otto B, de Meijer, Vincent E, Monbaliu, Diethard, Polak, Wojciech G, Slangen, Jules J.G, Troisi, Roberto I, Vanlander, Aude, de Jonge, Jeroen, Porte, Robert J

“…In a multicenter, controlled trial, patients undergoing transplantation of a liver from a donor after circulatory death were randomly assigned to receive the…”
Get full text

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver by Huch, Meritxell, Gehart, Helmuth, van Boxtel, Ruben, Hamer, Karien, Blokzijl, Francis, Verstegen, Monique M.A., Ellis, Ewa, van Wenum, Martien, Fuchs, Sabine A., de Ligt, Joep, van de Wetering, Marc, Sasaki, Nobuo, Boers, Susanne J., Kemperman, Hans, de Jonge, Jeroen, Ijzermans, Jan N.M., Nieuwenhuis, Edward E.S., Hoekstra, Ruurdtje, Strom, Stephen, Vries, Robert R.G., van der Laan, Luc J.W., Cuppen, Edwin, Clevers, Hans

“…Despite the enormous replication potential of the human liver, there are currently no culture systems available that sustain hepatocyte replication and/or…”
Get full text

Response by de Jonge and van der Worp to Letter Regarding Article, “Signs of Pulmonary Infection on Admission Chest Computed Tomography Are Associated With Pneumonia or Death in Patients With Acute Stroke” by de Jonge, Jeroen C., van der Worp, H. Bart

Get full text

Metoclopramide to Prevent Pneumonia in Patients With Stroke and a Nasogastric Tube: Data From the PRECIOUS Trial by Sluis, Wouter M, de Jonge, Jeroen C, Reinink, Hendrik, Woodhouse, Lisa J, Westendorp, Willeke F, Bath, Philip M, van de Beek, Diederik, van der Worp, H Bart

“…A randomized trial suggested that treatment with metoclopramide reduces the risk of pneumonia in patients with acute stroke and a nasogastric tube. We assessed…”
Get full text

Temporal Profile of Pneumonia After Stroke by de Jonge, Jeroen C., van de Beek, Diederik, Lyden, Patrick, Brady, Marian C., Bath, Philip M., van der Worp, H. Bart

“…The occurrence of pneumonia after stroke is associated with a higher risk of poor outcome or death. We assessed the temporal profile of pneumonia after stroke…”
Get full text

Signs of Pulmonary Infection on Admission Chest Computed Tomography Are Associated With Pneumonia or Death in Patients With Acute Stroke by de Jonge, Jeroen C., Takx, Richard A.P., Kauw, Frans, de Jong, Pim A., Dankbaar, Jan W., van der Worp, H. Bart

“…BACKGROUND AND PURPOSE—In patients with acute stroke, the occurrence of pneumonia has been associated with poor functional outcomes and an increased risk of…”
Get full text

Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules by Zhou, Guoying, Sprengers, Dave, Mancham, Shanta, Erkens, Remco, Boor, Patrick P.C., van Beek, Adriaan A., Doukas, Michail, Noordam, Lisanne, Campos Carrascosa, Lucia, de Ruiter, Valeska, van Leeuwen, Roelof W.F., Polak, Wojciech G., de Jonge, Jeroen, Groot Koerkamp, Bas, van Rosmalen, Belle, van Gulik, Thomas M., Verheij, Joanne, IJzermans, Jan N.M., Bruno, Marco J., Kwekkeboom, Jaap

“…[Display omitted] •NK cells and cytotoxic T cells infiltrate poorly into cholangiocarcinoma.•Regulatory T cells accumulate in cholangiocarcinoma.•PD1, CTLA4…”
Get full text

Modeling rotavirus infection and antiviral therapy using primary intestinal organoids by Yin, Yuebang, Bijvelds, Marcel, Dang, Wen, Xu, Lei, van der Eijk, Annemiek A., Knipping, Karen, Tuysuz, Nesrin, Dekkers, Johanna F., Wang, Yijin, de Jonge, Jeroen, Sprengers, Dave, van der Laan, Luc J.W., Beekman, Jeffrey M., ten Berge, Derk, Metselaar, Herold J., de Jonge, Hugo, Koopmans, Marion P.G., Peppelenbosch, Maikel P., Pan, Qiuwei

“…•3D-based primary intestinal organoids support the infection of both experimental and patient-derived rotavirus strains.•Rotavirus infection provokes the…”
Get full text

Clinical assessment of peripheral perfusion to predict postoperative complications after major abdominal surgery early: a prospective observational study in adults by van Genderen, Michel E, Paauwe, Jorden, de Jonge, Jeroen, van der Valk, Ralf J P, Lima, Alexandre, Bakker, Jan, van Bommel, Jasper

“…Altered peripheral perfusion is strongly associated with poor outcome in critically ill patients. We wanted to determine whether repeated assessments of…”
Get full text

Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells by Tüysüz, Nesrin, van Bloois, Louis, van den Brink, Stieneke, Begthel, Harry, Verstegen, Monique M. A., Cruz, Luis J., Hui, Lijian, van der Laan, Luc J. W., de Jonge, Jeroen, Vries, Robert, Braakman, Eric, Mastrobattista, Enrico, Cornelissen, Jan J., Clevers, Hans, ten Berge, Derk

“…Wnt signalling proteins are essential for culture of human organ stem cells in organoids, but most Wnt protein formulations are poorly active in serum-free…”
Get full text

Biomarkers to assess graft quality during conventional and machine preservation in liver transplantation by Verhoeven, Cornelia J, Farid, Waqar R.R, de Jonge, Jeroen, Metselaar, Herold J, Kazemier, Geert, van der Laan, Luc J.W

“…Summary A global rising organ shortage necessitates the use of extended criteria donors (ECD) for liver transplantation (LT). However, poor preservation and…”
Get full text

Outcome of Microscopic Incomplete Resection (R1) of Colorectal Liver Metastases in the Era of Neoadjuvant Chemotherapy by Ayez, Ninos, Lalmahomed, Zarina S., Eggermont, Alexander M. M., Ijzermans, Jan N. M., de Jonge, Jeroen, van Montfort, Kees, Verhoef, Cornelis

“…Background Data from patients with colorectal liver metastases (CRLM) who received neoadjuvant chemotherapy before resection were reviewed and evaluated to see…”
Get full text