Search Results - "Jermyn, K A"

An analysis of culmination in Dictyostelium using prestalk and stalk-specific cell autonomous markers by JERMYN, K. A, WILLIAMS, J. G

“…The ecmA (pDd63) and ecmB (pDd56) genes encode extracellular matrix proteins of the slime sheath and stalk tube of Dictyostelium discoideum. Using fusion genes…”
Get full text

A new anatomy of the prestalk zone in Dictyostelium by Jermyn, K. A, Duffy, K. T. I, Williams, J. G

“…The characteristic structure of the mature Dictyostelium culminant is created by the regionalized cellular differentiation and directed movement of prestalk…”
Get full text

Direct induction of Dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen by Williams, J G, Ceccarelli, A, McRobbie, S, Mahbubani, H, Kay, R R, Early, A, Berks, M, Jermyn, K A

“…We have isolated a gene that is very rapidly induced at the transcriptional level by DIF--a low molecular weight, diffusible factor necessary for stalk cell…”
Get more information

Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum by Morris, Howard R, Taylor, Graham W, Masento, Mark S, Jermyn, Keith A, Kay, Robert R

“…Morphogens are signal molecules presumed to exist in embryos and to be involved in establishing the spatial pattern of cells during development…”
Get full text

Origins of the prestalk-prespore pattern in Dictyostelium development by Williams, J G, Duffy, K T, Lane, D P, McRobbie, S J, Harwood, A J, Traynor, D, Kay, R R, Jermyn, K A

“…Using cell-autonomous markers we have traced the origins of prespore cells and two types of prestalk cells (pstA and pstB cells) during slug formation. We show…”
Get more information

Growing and developing Dictyostelium cells express different ras genes by Robbins, S.M, Williams, J.G, Jermyn, K.A, Speigelman, G.B, Weeks, G

“…The expression of ras-related protein in the cellular slime mold Dictyostelium discoideum is developmentally regulated. It was previously reported that…”
Get full text

Formation and anatomy of the prestalk zone of Dictyostelium by WILLIAMS, J. G, JERMYN, K. A, DUFFY, K. T

“…The pDd63 and pDd56 genes encode extracellular matrix proteins which, respectively, surround the migratory slug and mature stalk cells. Both genes are…”
Get full text

SH2 Signaling in a Lower Eukaryote: A STAT Protein That Regulates Stalk Cell Differentiation in Dictyostelium by Kawata, Takefumi, Shevchenko, Andrej, Fukuzawa, Masashi, Jermyn, Keith A, Totty, Nicholas F, Zhukovskaya, Natasha V, Sterling, Alistair E, Mann, Matthias, Williams, Jeffrey G

“…The TTGA-binding factor is a transcriptional regulator activated by DIF, the chlorinated hexaphenone that induces prestalk cell differentiation in…”
Get full text

Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum by Morris, H.R, Masento, M.S, Taylor, G.W, Jermyn, K.A, Kay, R.R

“…Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium…”
Get full text

Nature and distribution of the morphogen DIF in the Dictyostelium slug by Brookman, J J, Jermyn, K A, Kay, R R

“…The Dictyostelium slug contains a simple anterior-posterior pattern of prestalk and prespore cells. It is likely that DIF, the morphogen which induces stalk…”
Get full text

A possible morphogen controlling differentiation in Dictyostelium by Kay, R. R, Jermyn, K. A

Get full text

Cell patterning in Dictyostelium by Gross, J.D, Town, C.D, Brookman, J.J, Jermyn, K.A, Peacey, M.J, Kay, R.R

“…We summarize studies on stalk and spore cell formation in D. discoideum cell monolayers, aimed at revealing factors involved in controlling the…”
Get full text

Two DIF-inducible, prestalk-specific mRNAs of Dictyostelium encode extracellular matrix proteins of the slug by McRobbie, S J, Jermyn, K A, Duffy, K, Blight, K, Williams, J G

“…The migratory slug of Dictyostelium discoideum is surrounded by, and continuously synthesizes, an extracellular protein-cellulose matrix known as the slime…”
Get full text

Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis by Mohanty, S, Jermyn, K A, Early, A, Kawata, T, Aubry, L, Ceccarelli, A, Schaap, P, Williams, J G, Firtel, R A

“…Dd-STATa is a structural and functional homologue of the metazoan STAT (Signal Transducer and Activator of Transcription) proteins. We show that Dd-STATa null…”
Get full text

Unexpected localisation of cells expressing a prespore marker of Dictyostelium discoideum by Harwood, A J, Early, A E, Jermyn, K A, Williams, J

“…We show that the anterior, prestalk region of the Dictyostelium slug contains cells which express, or have expressed, a prespore-specific marker. We term these…”
Get more information

Structural and functional characterization of a Dictyostelium gene encoding a DIF inducible, prestalk-enriched mRNA sequence by CECCARELLI, A, MCROBBIE, S. J, JERMYN, K. A, DUFFY, K, EARLY, A, WILLIAMS, J. G

“…The pDd56 mRNA sequence is highly enriched in prestalk over prespore cells and is inducible by DIF, the putative Dictyostelium stalk-specific morphogen. We…”
Get full text

An F-Box/WD40 Repeat-Containing Protein Important for Dictyostelium Cell-Type Proportioning, Slug Behaviour, and Culmination by Nelson, Margaret K, Clark, Alexandra, Abe, Tomoaki, Nomura, Anson, Yadava, Negendra, Funair, Chanin J, Jermyn, Keith A, Mohanty, Sudhasri, Firtel, Richard A, Williams, Jeffrey G

“…FbxA is a novel member of a family of proteins that contain an F-box and WD40 repeats and that target specific proteins for degradation via proteasomes. In…”
Get full text

Two distinct classes of prestalk-enriched mRNA sequences in Dictyostelium discoideum by Jermyn, K A, Berks, M, Kay, R R, Williams, J G

“…We have isolated cDNA clones derived from three mRNA sequences which are inducible by DIF, the putative stalk-specific morphogen of Dictyostelium. The three…”
Get full text

A possible morphogen controlling differentiation in Dictyostelium by Kay, R R, Jermyn, K A

“…The complex morphology of a higher organism is generated partly by such developmental processes as cell movement and cohesion but also by a social interaction…”
Get full text

Chlorine-containing compounds produced during Dictyostelium development : detection by labelling with 36Cl by KAY, R. R, TAYLOR, G. W, JERMYN, K. A, TRAYNOR, D

“…DIF-1 [Differentiation-Inducing Factor 1; 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one] is a novel chlorinated signal molecule that induces…”
Get full text