Search Results - "Jerlich, Andreas"

Pathways of phospholipid oxidation by HOCl in human LDL detected by LC-MS by Jerlich, Andreas, Pitt, Andrew R, Schaur, R.Jörg, Spickett, Corinne M

“…A wealth of evidence now indicates that low-density lipoprotein (LDL) must be modified to promote atherosclerosis, and that this may involve oxidants released…”
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Human Low Density Lipoprotein as a Target of Hypochlorite Generated by Myeloperoxidase by Jerlich, Andreas, Fabjan, Judith S., Tschabuschnig, Sylvia, Smirnova, Angela V., Horakova, Lubica, Hayn, Marianne, Auer, Helga, Guttenberger, Helmut, Leis, Hans-Jörg, Tatzber, Franz, Waeg, Georg, Schaur, R.Jörg

“…The aim of this study was to further clarify which part of human low density lipoprotein (LDL) is attacked by the MPO/H 2O 2/Cl −-system and which reactive…”
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Kinetics of tryptophan oxidation in plasma lipoproteins by myeloperoxidase‐generated HOCl by Jerlich, Andreas, Hammel, Michal, Nigon, Fabienne, Chapman, M. John, Schaur, R. Jörg

“…The relative susceptibility of the apoprotein components of human lipoproteins [high‐density lipoprotein (HDL) and low‐density lipoprotein (LDL)] and their…”
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The reactions of hypochlorous acid, the reactive oxygen species produced by myeloperoxidase, with lipids by Spickett, C M, Jerlich, A, Panasenko, O M, Arnhold, J, Pitt, A R, Stelmaszyńska, T, Schaur, R J

“…Myeloperoxidase (MPO), an abundant enzyme in phagocytes, has been implicated in the pathogenesis of various inflammatory diseases including atherosclerosis…”
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Detection of phospholipid oxidation in oxidatively stressed cells by reversed-phase HPLC coupled with positive-ionization electroscopy MS by SPICKETT, Corinne M., RENNIE, Nicola, WINTER, Helen, ZAMBONIN, Laura, LANDI, Laura, JERLICH, Andreas, SCHAUR, R. Jörg, PITT, Andrew R.

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The formation of phosphatidylcholine oxidation products by stimulated phagocytes by Jerlich, Andreas, Schaur, R Jörg, Pitt, Andrew R, Spickett, Corinne M

“…Phagocytic cells produce a variety of oxidants as part of the immune defence, which react readily both with proteins and lipids, and could contribute to the…”
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Detection of phospholipid oxidation in oxidatively stressed cells by reversed-phase HPLC coupled with positive-ionization electroscopy MS by SPICKETT, Corinne M., RENNIE, Nicola, WINTER, Helen, ZAMBONIN, Laura, LANDI, Laura, JERLICH, Andreas, SCHAUR, R. Jörg, PITT, Andrew R.

“…Measurement of lipid peroxidation is a commonly used method of detecting oxidative damage to biological tissues, but the most frequently used methods,…”
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Comparison of HOCl traps with myeloperoxidase inhibitors in prevention of low density lipoprotein oxidation by Jerlich, Andreas, Fritz, Gerhard, Kharrazi, Hadi, Hammel, Michal, Tschabuschnig, Sylvia, Glatter, Otto, Schaur, R.Jörg

“…In this study, the production of the highly toxic oxidant hypochlorous acid (HOCl) by the phagocytic enzyme myeloperoxidase (MPO) was quantitated and the…”
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