Search Results - "Jeremy Turner"

Hypercalcaemia – presentation and management by Turner, Jeremy J O

“…Hypercalcaemia is a common disorder normally caused by primary hyperparathyroidism (PHPT) or malignancy. A proportion of cases present as an emergency, which…”
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Noise and Vibration in the Vivarium: Recommendations for Developing a Measurement Plan by Turner, Jeremy G

“…Noise and vibration are present in every room of laboratory animal vivaria, with great variability from room-to-room and facility-to-facility. Such stimuli are…”
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UK national chronic hypoparathyroidism audit by Kiam, Jian Shen, Sharma, Vivek, Glenister, Liz, Fraser, William D., Turner, Jeremy J. O.

“…Objectives Individuals with chronic hypoparathyroidism may experience suboptimal medical care with high frequency of unplanned hospitalisation and iatrogenic…”
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Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice by Rosell, Meritxell, Kaforou, Myrsini, Frontini, Andrea, Okolo, Anthony, Chan, Yi-Wah, Nikolopoulou, Evanthia, Millership, Steven, Fenech, Matthew E, MacIntyre, David, Turner, Jeremy O, Moore, Jonathan D, Blackburn, Edith, Gullick, William J, Cinti, Saverio, Montana, Giovanni, Parker, Malcolm G, Christian, Mark

“…Brown adipocytes dissipate energy, whereas white adipocytes are an energy storage site. We explored the plasticity of different white adipose tissue depots in…”
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Constitutive P2Y2 receptor activity regulates basal lipolysis in human adipocytes by Ali, Seema B., Turner, Jeremy J. O., Fountain, Samuel J.

“…ABSTRACT White adipocytes are key regulators of metabolic homeostasis, which release stored energy as free fatty acids via lipolysis. Adipocytes possess both…”
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Single unit hyperactivity and bursting in the auditory thalamus of awake rats directly correlates with behavioural evidence of tinnitus by Kalappa, Bopanna I., Brozoski, Thomas J., Turner, Jeremy G., Caspary, Donald M.

“…Key points Medial geniculate body (MGB) single units recorded from sound‐exposed animals with behavioural evidence of tinnitus exhibits enhanced spontaneous…”
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Drug selection for inner ear therapy by Salt, Alec N, Turner, Jeremy G

“…One of the primary tenets in pharmacotherapy is that the applied drug must reach the target tissue at therapeutic concentration. For many therapies intended to…”
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Assessing Glycemic Control in Maintenance Hemodialysis Patients With Type 2 Diabetes by Kazempour-Ardebili, Sara, Lecamwasam, Varunika L, Dassanyake, Thushara, Frankel, Andrew H, Tam, Frederick W.K, Dornhorst, Anne, Frost, Gary, Turner, Jeremy J.O

“…OBJECTIVE: Optimizing glycemic control in diabetic patients undergoing maintenance hemodialysis requires accurate assessment. We hypothesize that 1) 48-h…”
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Inhibitory neurotransmission, plasticity and aging in the mammalian central auditory system by Caspary, Donald M, Ling, Lynne, Turner, Jeremy G, Hughes, Larry F

“…Aging and acoustic trauma may result in partial peripheral deafferentation in the central auditory pathway of the mammalian brain. In accord with homeostatic…”
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Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment by Shafat, Manar S., Oellerich, Thomas, Mohr, Sebastian, Robinson, Stephen D., Edwards, Dylan R., Marlein, Christopher R., Piddock, Rachel E., Fenech, Matthew, Zaitseva, Lyubov, Abdul-Aziz, Amina, Turner, Jeremy, Watkins, Johnathan A., Lawes, Matthew, Bowles, Kristian M., Rushworth, Stuart A.

“…Despite currently available therapies, most patients diagnosed with acute myeloid leukemia (AML) die of their disease. Tumor-host interactions are critical for…”
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Mice with behavioral evidence of tinnitus exhibit dorsal cochlear nucleus hyperactivity because of decreased GABAergic inhibition by Middleton, Jason W, Kiritani, Taro, Pedersen, Courtney, Turner, Jeremy G, Shepherd, Gordon M.G, Tzounopoulos, Thanos

“…Tinnitus has been associated with increased spontaneous and evoked activity, increased neural synchrony, and reorganization of tonotopic maps of auditory…”
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Hypercalcaemia and primary hyperparathyroidism by Kiam, Jian Shen, Turner, Jeremy J O

“…Hypercalcaemia is most commonly caused by primary hyperparathyroidism (PHPT) or malignancy. PHPT is common, affects women more than men, and is usually caused…”
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Diagnostic challenges due to phenocopies: lessons from Multiple Endocrine Neoplasia type1 (MEN1) by Turner, Jeremy J.O, Christie, Paul T, Pearce, Simon H.S, Turnpenny, Peter D, Thakker, Rajesh V

“…Phenocopies may confound the clinical diagnoses of hereditary disorders. We report phenocopies in Multiple Endocrine Neoplasia type 1 (MEN1), an autosomal…”
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Effects of noise exposure on development of tinnitus and hyperacusis: Prevalence rates 12 months after exposure in middle-aged rats by Turner, Jeremy G., Larsen, Deb

“…Fischer Brown Norway (FBN) rats (n = 233) were unilaterally exposed to 12 different combinations of noise intensity, duration, and spectrum, while 46 rats…”
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Noise as an Extrinsic Variable in the Animal Research Facility by Turner, PhD, Jeremy G, Manker, BA, John R

“…Animal research facilities are noisy environments. The high air change rates required in animal housing spaces tend to create higher noise levels from the…”
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Diminished cortical inhibition in an aging mouse model of chronic tinnitus by Llano, Daniel A, Turner, Jeremy, Caspary, Donald M

“…Flavoprotein autofluorescence imaging was used to examine auditory cortical synaptic responses in aged animals with behavioral evidence of tinnitus and hearing…”
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Enhanced GABAA-Mediated Tonic Inhibition in Auditory Thalamus of Rats with Behavioral Evidence of Tinnitus by Sametsky, Evgeny A, Turner, Jeremy G, Larsen, Deb, Ling, Lynne, Caspary, Donald M

“…Accumulating evidence suggests a role for inhibitory neurotransmitter dysfunction in the pathology of tinnitus. Opposing hypotheses proposed either a…”
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Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites by HANNAN, Fadil M, NESBIT, M. Andrew, LEMOS, Manuel C, BOWL, Michael R, BOUILLON, Roger, BRAIN, Caroline, BRIDGES, Nicola, BURREN, Christine, CONNELL, John M, HEIKE JUNG, MARKS, Eileen, MCCREDIE, David, CHEN ZHANG, MUGHAL, Zulf, RODDA, Christine, TOLLEFSEN, Sherida, BROWN, Edward M, YANG, Jenny J, THAKKER, Rajesh V, CRANSTON, Treena, CURLEY, Alan J, HARDING, Brian, FRATTER, Carl, RUST, Nigel, CHRISTIE, Paul T, TURNER, Jeremy J. O

“…The calcium-sensing receptor (CaSR) is a G-protein-coupled receptor that has an extracellular bilobed venus flytrap domain (VFTD) predicted to contain five…”
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Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma by Bauer, Carol A., Turner, Jeremy G., Caspary, Donald M., Myers, Kristin S., Brozoski, Thomas J.

“…A longstanding hypothesis is that tinnitus, the perception of sound without an external acoustic source, is triggered by a distinctive pattern of cochlear hair…”
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Nonsteroidal anti-inflammatory drugs increase TNF production in rheumatoid synovial membrane cultures and whole blood by Page, Theresa H, Turner, Jeremy J O, Brown, Anthony C, Timms, Emma M, Inglis, Julia J, Brennan, Fionula M, Foxwell, Brian M J, Ray, Keith P, Feldmann, Marc

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase activity and hence PG production. However, the ability of NSAIDs to ameliorate pain and…”
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