Search Results - "Jeremy R. H. Tame"

Molecular basis of hemoglobin adaptation in the high-flying bar-headed goose by Natarajan, Chandrasekhar, Jendroszek, Agnieszka, Kumar, Amit, Weber, Roy E, Tame, Jeremy R H, Fago, Angela, Storz, Jay F

“…During the adaptive evolution of a particular trait, some selectively fixed mutations may be directly causative and others may be purely compensatory. The…”
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Structural basis of CXC chemokine receptor 1 ligand binding and activation by Ishimoto, Naito, Park, Jae-Hyun, Kawakami, Kouki, Tajiri, Michiko, Mizutani, Kenji, Akashi, Satoko, Tame, Jeremy R. H., Inoue, Asuka, Park, Sam-Yong

“…Neutrophil granulocytes play key roles in innate immunity and shaping adaptive immune responses. They are attracted by chemokines to sites of infection and…”
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The structural basis for an essential subunit interaction in influenza virus RNA polymerase by Park, Sam-Yong, Kawaguchi, Atsushi, Yoshida, Hisashi, Obayashi, Eiji, Nagata, Kyosuke, Tame, Jeremy R. H, Shibayama, Naoya, Kawai, Fumihiro

“…Influenza A virus is a major human and animal pathogen with the potential to cause catastrophic loss of life. The virus reproduces rapidly, mutates frequently…”
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The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM by Takahashi, Katsuya, Lee, Yongchan, Fago, Angela, Bautista, Naim M., Storz, Jay F., Kawamoto, Akihiro, Kurisu, Genji, Nishizawa, Tomohiro, Tame, Jeremy R. H.

“…The principal effect controlling the oxygen affinity of vertebrate haemoglobins (Hbs) is the allosteric switch between R and T forms with relatively high and…”
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Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface by Heo, Yunseok, Ishimoto, Naito, Jeon, Ye-Eun, Yun, Ji-Hye, Ohki, Mio, Anraku, Yuki, Sasaki, Mina, Kita, Shunsuke, Fukuhara, Hideo, Ikuta, Tatsuya, Kawakami, Kouki, Inoue, Asuka, Maenaka, Katsumi, Tame, Jeremy R. H, Lee, Weontae, Park, Sam-Yong

“…Galanin is a neuropeptide expressed in the central and peripheral nervous systems, where it regulates various processes including neuroendocrine release,…”
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Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2 by Park, Jae-Hyun, Kawakami, Kouki, Ishimoto, Naito, Ikuta, Tatsuya, Ohki, Mio, Ekimoto, Toru, Ikeguchi, Mitsunori, Lee, Dong-Sun, Lee, Young-Ho, Tame, Jeremy R. H., Inoue, Asuka, Park, Sam-Yong

“…Hydroxycarboxylic acid receptors (HCAR1, HCAR2, and HCAR3) transduce G i/o signaling upon biding to molecules such as lactic acid, butyric acid and…”
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Structural basis for hepatitis B virus restriction by a viral receptor homologue by Shionoya, Kaho, Park, Jae-Hyun, Ekimoto, Toru, Takeuchi, Junko S., Mifune, Junki, Morita, Takeshi, Ishimoto, Naito, Umezawa, Haruka, Yamamoto, Kenichiro, Kobayashi, Chisa, Kusunoki, Atsuto, Nomura, Norimichi, Iwata, So, Muramatsu, Masamichi, Tame, Jeremy R. H., Ikeguchi, Mitsunori, Park, Sam-Yong, Watashi, Koichi

“…Macaque restricts hepatitis B virus (HBV) infection because its receptor homologue, NTCP (mNTCP), cannot bind preS1 on viral surface. To reveal how mNTCP loses…”
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Structural basis for the recognition of human hemoglobin by the heme-acquisition protein Shr from Streptococcus pyogenes by Senoo, Akinobu, Hoshino, Masato, Shiomi, Toshiki, Nakakido, Makoto, Nagatoishi, Satoru, Kuroda, Daisuke, Nakagawa, Ichiro, Tame, Jeremy R. H., Caaveiro, Jose M. M., Tsumoto, Kouhei

“…In Gram-positive bacteria, sophisticated machineries to acquire the heme group of hemoglobin (Hb) have evolved to extract the precious iron atom contained in…”
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Capturing the Hemoglobin Allosteric Transition in a Single Crystal Form by Shibayama, Naoya, Sugiyama, Kanako, Tame, Jeremy R. H, Park, Sam-Yong

“…Allostery in many oligomeric proteins has been postulated to occur via a ligand-binding-driven conformational transition from the tense (T) to relaxed (R)…”
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Structural Basis of Sequential and Concerted Cooperativity by Morea, Veronica, Angelucci, Francesco, Tame, Jeremy R H, Di Cera, Enrico, Bellelli, Andrea

“…Allostery is a property of biological macromolecules featuring cooperative ligand binding and regulation of ligand affinity by effectors. The definition was…”
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The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata by Kamata, Kenichi, Mizutani, Kenji, Takahashi, Katsuya, Marchetti, Roberta, Silipo, Alba, Addy, Christine, Park, Sam-Yong, Fujii, Yuki, Fujita, Hideaki, Konuma, Tsuyoshi, Ikegami, Takahisa, Ozeki, Yasuhiro, Tame, Jeremy R. H.

“…SeviL is a recently isolated lectin found to bind to the linear saccharides of the ganglioside GM1b (Neu5Ac α (2-3)Gal β (1-3)GalNAc β (1-4)Gal β (1-4)Glc) and…”
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Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle by HANSMAN, Grant S, TAYLOR, David W, KATAYAMA, Kazuhiko, MURATA, Kazuyoshi, KWONG, Peter D, MCLELLAN, Jason S, SMITH, Thomas J, GEORGIEV, Ivelin, TAME, Jeremy R. H, PARK, Sam-Yong, YAMAZAKI, Makoto, GONDAIRA, Fumio, MIKI, Motohiro

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Using symmetry to drive new protein assemblies by Tame, Jeremy R. H.

“…Recent improvements in de novo protein design are likely to support a broad range of applications, but larger complexes will be easier to create if a building…”
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Biomineralization of a Cadmium Chloride Nanocrystal by a Designed Symmetrical Protein by Voet, Arnout R. D., Noguchi, Hiroki, Addy, Christine, Zhang, Kam Y. J., Tame, Jeremy R. H.

“…We have engineered a metal‐binding site into the novel artificial β‐propeller protein Pizza. This new Pizza variant carries two nearly identical domains per…”
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Influence of structural symmetry on protein dynamics by Matsunaga, Yasuhiro, Koike, Ryotaro, Ota, Motonori, Tame, Jeremy R H, Kidera, Akinori

“…Structural symmetry in homooligomeric proteins has intrigued many researchers over the past several decades. However, the implication of protein symmetry is…”
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Autotransporter passenger proteins: virulence factors with common structural themes by Nishimura, Kaoru, Tajima, Nami, Yoon, Young-Ho, Park, Sam-Yong, Tame, Jeremy R. H.

“…Autotransporter proteins are virulence factors associated with a wide variety of diseases caused by pathogenic Gram-negative bacteria, and they play a variety…”
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Limited tolerance towards folded elements during secretion of the autotransporter Hbp by Jong, Wouter S.P, ten Hagen-Jongman, Corinne M, den Blaauwen, Tanneke, Jan Slotboom, Dirk, Tame, Jeremy R.H, Wickström, David, de Gier, Jan-Willem, Otto, Ben R, Luirink, Joen

“…Many virulence factors secreted by pathogenic Gram-negative bacteria belong to the autotransporter (AT) family. ATs consist of a passenger domain, which is the…”
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NMR-guided directed evolution by Bhattacharya, Sagar, Margheritis, Eleonora G., Takahashi, Katsuya, Kulesha, Alona, D’Souza, Areetha, Kim, Inhye, Yoon, Jennifer H., Tame, Jeremy R. H., Volkov, Alexander N., Makhlynets, Olga V., Korendovych, Ivan V.

“…Directed evolution is a powerful tool for improving existing properties and imparting completely new functionalities to proteins 1 – 4 . Nonetheless, its…”
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Enzyme dynamics—a brief review by Tame, Jeremy R. H.

“…Debate has been simmering for some years regarding the importance of internal thermal motions of enzymes to catalysis. Recent developments in protein design…”
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Early-stage dynamics of chloride ion–pumping rhodopsin revealed by a femtosecond X-ray laser by Yun, Ji-Hye, Li, Xuanxuan, Yue, Jianing, Park, Jae-Hyun, Jin, Zeyu, Li, Chufeng, Hu, Hao, Shi, Yingchen, Pandey, Suraj, Carbajo, Sergio, Boutet, Sébastien, Hunter, Mark S., Liang, Mengning, Sierra, Raymond G., Lane, Thomas J., Zhou, Liang, Weierstall, Uwe, Zatsepin, Nadia A., Ohki, Mio, Tame, Jeremy R. H., Park, Sam-Yong, Spence, John C. H., Zhang, Wenkai, Schmidt, Marius, Lee, Weontae, Liu, Haiguang

“…Chloride ion–pumping rhodopsin (ClR) in some marine bacteria utilizes light energy to actively transport Cl⁻ into cells. How the ClR initiates the transport is…”
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