Search Results - "Jerde, CR"

Quantitative Contribution of rs75017182 to Dihydropyrimidine Dehydrogenase mRNA Splicing and Enzyme Activity by Nie, Q, Shrestha, S, Tapper, EE, Trogstad‐Isaacson, CS, Bouchonville, KJ, Lee, AM, Wu, R, Jerde, CR, Wang, Z, Kubica, PA, Offer, SM, Diasio, RB

“…Dihydropyrimidine dehydrogenase (DPD; DPYD gene) variants have emerged as reliable predictors of adverse toxicity to the chemotherapy agent 5‐fluorouracil…”
Get full text

Novel Deleterious Dihydropyrimidine Dehydrogenase Variants May Contribute to 5‐Fluorouracil Sensitivity in an East African Population by Elraiyah, T, Jerde, CR, Shrestha, S, Wu, R, Nie, Q, Giama, NH, Sarangi, V, Roberts, LR, Offer, SM, Diasio, RB

“…Clinical studies have identified specific genetic variants in dihydropyrimidine dehydrogenase (DPD; DPYD gene) as predictors of severe adverse toxicity to the…”
Get full text