Search Results - "Jeoung, Myoungkun"

HUWE1 Is a Molecular Link Controlling RAF-1 Activity Supported by the Shoc2 Scaffold by Jang, Eun Ryoung, Shi, Ping, Bryant, Jamal, Chen, Jing, Dukhande, Vikas, Gentry, Matthew S., Jang, HyeIn, Jeoung, Myoungkun, Galperin, Emilia

“…Scaffold proteins play a critical role in controlling the activity of the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway. Shoc2 is a leucine-rich…”
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Estrogen Receptor Alpha (ESR1)-Dependent Regulation of the Mouse Oviductal Transcriptome by Cerny, Katheryn L, Ribeiro, Rosanne A C, Jeoung, Myoungkun, Ko, CheMyong, Bridges, Phillip J

“…Estrogen receptor-α (ESR1) is an important transcriptional regulator in the mammalian oviduct, however ESR1-dependent regulation of the transcriptome of this…”
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Functional Integration of the Conserved Domains of Shoc2 Scaffold by Jeoung, Myoungkun, Abdelmoti, Lina, Jang, Eun Ryoung, Vander Kooi, Craig W, Galperin, Emilia

“…Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases 1 and 2 (ERK1/2). Shoc2 is also proposed to interact with RAS and…”
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Identification of a Novel Role for Endothelins within the Oviduct by Jeoung, Myoungkun, Lee, Sungeun, Hawng, Hee-kyung, Cheon, Yong-Pil, Jeong, Youn Kyung, Gye, Myung Chan, Iglarz, Marc, Ko, CheMyong, Bridges, Phillip J

“…Endothelins were first identified as potent vasoactive peptides; however, diversity in the biological function of these hormones is now evident. We have…”
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Cyclic regulation of apoptotic gene expression in the mouse oviduct by Jeoung, Myoungkun, Bridges, Phillip J

“…The oviduct is a dynamic structure whose function relies upon cyclic changes in the morphology of both ciliated and secretory luminal epithelial cells…”
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Production and binding of endothelin-2 (EDN2) in the rat ovary: endothelin receptor subtype A (EDNRA)-mediated contraction by Bridges, Phillip J, Jo, Misung, Al Alem, Linah, Na, Giyoun, Su, Wen, Gong, Ming C, Jeoung, Myoungkun, Ko, Chemyong

“…Endothelin-2 (EDN2)-mediated contraction has been proposed as a final mechanical signal facilitating ovulation. The objectives herein were to determine (1)…”
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Data set for transcriptional response to depletion of the Shoc2 scaffolding protein by Rouchka, Eric C., Jeoung, Myoungkun, Jang, Eun Ryoung, Liu, Jinpeng, Wang, Chi, Li, Xiaohong, Galperin, Emilia

“…The Suppressor of Clear, Caenorhabditis elegans Homolog (SHOC2) is a scaffold protein that positively modulates activity of the RAS/ERK1/2 MAP kinase signaling…”
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Follicle-stimulating Hormone Interacts with Exoloop 3 of the Receptor by Sohn, Johann, Ryu, KiSung, Sievert, Gail, Jeoung, MyoungKun, Ji, Inhae, Ji, Tae H.

“…The human follicle-stimulating hormone (FSH) receptor consists of two distinct domains of ∼330 amino acids, the N-terminal extracellular exodomain and…”
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Orientation of Follicle-stimulating Hormone (FSH) Subunits Complexed with the FSH Receptor by Sohn, Johann, Youn, HyeSook, Jeoung, MyoungKun, Koo, YongBum, Yi, ChongSeoung, Ji, Inhae, Ji, Tae H.

“…Follicle-stimulating hormone (FSH) comprises an α subunit and a β subunit, whereas the FSH receptor consists of two halves with distinct functions: the…”
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Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5 by Jang, Eun Ryoung, Jang, HyeIn, Shi, Ping, Popa, Gabriel, Jeoung, Myoungkun, Galperin, Emilia

“…The scaffold protein Shoc2 accelerates activity of the ERK1 and ERK2 (ERK1/2, also known as MAPK3 and MAPK1) pathway. Mutations in Shoc2 result in Noonan-like…”
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Determination of Cyclic Changes in the Expression of Apoptotic Genes in the Mouse Oviduct by Jeoung, Myoungkun, Bridges, Phillip

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Hormone Interactions to Leu-rich Repeats in the Gonadotropin Receptors by Jeoung, MyoungKun, Phang, Tzulip, Song, Yong Sang, Ji, Inhae, Ji, Tae H.

“…Human chorionic gonadotropin (hCG) binds to the extracellular N-terminal domain, exodomain, of its receptor, and the resulting hCG-exodomain complex is thought…”
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A Novel SHOC2 Variant in Rasopathy by Hannig, Vickie, Jeoung, Myoungkun, Jang, Eun Ryoung, Phillips III, John A., Galperin, Emilia

“…ABSTRACT Rasopathies are a group of genetic disorders caused by germline mutations in multiple genes of the Extracellular signal‐Regulated Kinases 1 and 2…”
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Shoc2-tranduced ERK1/2 motility signals — Novel insights from functional genomics by Jeoung, Myoungkun, Jang, Eun Ryoung, Liu, Jinpeng, Wang, Chi, Rouchka, Eric C., Li, Xiaohong, Galperin, Emilia

“…The extracellular signal-regulated kinase 1 and 2 (ERK1/2) pathway plays a central role in defining various cellular fates. Scaffold proteins modulating ERK1/2…”
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Methodology matters: IVF versus ICSI and embryonic gene expression by Bridges, Phillip J, Jeoung, Myoungkun, Kim, Heyoung, Kim, Jung Ho, Lee, Dong Ryul, Ko, CheMyong, Baker, Doris J

“…Abstract The use of assisted reproduction treatment, especially intracytoplasmic sperm injection (ICSI), is now linked to a range of adverse consequences, the…”
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Visualizing of signaling proteins on endosomes utilizing knockdown and reconstitution approach by Jeoung, Myoungkun, Galperin, Emilia

“…Spatial distribution of intracellular signaling molecules and assembly of signaling complexes are yet to be fully understood. Studies of signaling events in…”
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Hematopoetic Prostaglandin D Synthase: An ESR1-Dependent Oviductal Epithelial Cell Synthase by Bridges, Phillip J, Jeoung, Myoungkun, Shim, Sarah, Park, Ji Yeon, Lee, Jae Eun, Sapsford, Lindsay A, Trudgen, Kourtney, Ko, Chemyong, Gye, Myung Chan, Jo, Misung

“…Oviductal disease is a primary cause of infertility, a problem that largely stems from excessive inflammation of this key reproductive organ. Our poor…”
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Kalirin is under-expressed in Alzheimer's disease hippocampus by Youn, HyeSook, Jeoung, MyoungKun, Koo, YongBum, Ji, Hanlee, Markesbery, William R, Ji, Inhae, Ji, Tae H

“…To identify genes aberrantly expressed in the brain of individuals with Alzheimer's Disease (AD), we analyzed RNA extracts from the hippocampus and cerebellum…”
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Methodology Matters: In Vitro Fertilization Versus Intracytoplasmic Sperm Injection and Embryonic Gene Expression in the Mouse by Bridges, Phillip J., Jeoung, Myoungkun, Kim, Heyoung, Kim, Jung Ho, Lee, Dong Ryul, Ko, CheMyong, Baker, Doris J.

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Hematopoietic Prostaglandin D Synthase: An ESR1-Dependent Synthase Required for Oviductal Epithelial Cell Viability by Jeoung, Myoungkun J., Shim, Sarah, Sapsford, Lindsay, Trudgen, Kourtney, Ko, CheMyong, Gye, Myung Chan, Bridges, Phillip J.

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