Search Results - "Jeong, Jae Wook"

Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis? by Marquardt, Ryan M, Kim, Tae Hoon, Shin, Jung-Ho, Jeong, Jae-Wook

“…In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly regulated, dynamic interplay to drive a normal menstrual cycle and…”
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Local and systemic factors and implantation: what is the evidence? by Fox, Chelsea, M.D, Morin, Scott, M.D, Jeong, Jae-Wook, Ph.D, Scott, Richard T., M.D, Lessey, Bruce A., M.D., Ph.D

“…Significant progress has been made in the understanding of embryonic competence and endometrial receptivity since the inception of assisted reproductive…”
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Loss of MIG-6 results in endometrial progesterone resistance via ERBB2 by Yoo, Jung-Yoon, Kim, Tae Hoon, Shin, Jung-Ho, Marquardt, Ryan M., Müller, Ulrich, Fazleabas, Asgerally T., Young, Steven L., Lessey, Bruce A., Yoon, Ho-Geun, Jeong, Jae-Wook

“…Female subfertility is highly associated with endometriosis. Endometrial progesterone resistance is suggested as a crucial element in the development of…”
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WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse by Franco, Heather L., Dai, Daisy, Lee, Kevin Y., Rubel, Cory A., Roop, Dennis, Boerboom, Derek, Jeong, Jae‐Wook, Lydon, John P., Bagchi, Indrani C., Bagchi, Milan K., DeMayo, Francesco J.

“…ABSTRACT WNT4, a member of the Wnt family of ligands, is critical for the development of the female reproductive tract. Analysis of Wnt4 expression in the…”
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KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance by Yoo, Jung-Yoon, Kim, Tae Hoon, Fazleabas, Asgerally T., Palomino, Wilder A., Ahn, Soo Hyun, Tayade, Chandrakant, Schammel, David P., Young, Steven L., Jeong, Jae-Wook, Lessey, Bruce A.

“…Endometriosis is an inflammatory condition that is associated with progesterone resistance and cell proliferation, resulting in pain, infertility and pregnancy…”
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Interleukin-6 (IL-6) Activates the NOTCH1 Signaling Pathway Through E-Proteins in Endometriotic Lesions by Song, Yong, Su, Ren-Wei, Joshi, Niraj R, Kim, Tae Hoon, Lessey, Bruce A, Jeong, Jae-Wook, Fazleabas, Asgerally T

“…Abstract Context NOTCH signaling is activated in endometriotic lesions, but the exact mechanisms remains unclear. IL-6, which is increased in the peritoneal…”
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SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh by Wang, Xiaoqiu, Li, Xilong, Wang, Tianyuan, Wu, San-Pin, Jeong, Jae-Wook, Kim, Tae Hoon, Young, Steven L., Lessey, Bruce A., Lanz, Rainer B., Lydon, John P., DeMayo, Francesco J.

“…Mammalian pregnancy depends on the ability of the uterus to support embryo implantation. Previous studies reveal the Sox17 gene as a downstream target of the…”
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Signal transducer and activator of transcription‐3 (Stat3) plays a critical role in implantation via progesterone receptor in uterus by Lee, Jae Hee, Kim, Tae Hoon, Oh, Seo Jin, Yoo, Jung‐Yoon, Akira, Shizuo, Ku, Bon Jeong, Lydon, John P., Jeong, Jae‐Wook

“…Recent studies have shown that activation of the signal transducer and activator of transcription‐3 (Stat3) is required for decidualization, interacting with…”
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Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse by Afshar, Yalda, Jeong, Jae‐Wook, Roqueiro, Damian, DeMayo, Franco, Lydon, John, Radtke, Freddy, Radnor, Rachel, Miele, Lucio, Fazleabas, Asgerally

“…ABSTRACT Uterine receptivity implies a dialogue between the hormonally primed maternal endometrium and the free‐floating blastocyst. Endometrial stromal cells…”
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Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function by Franco, Heather L., Rubel, Cory A., Large, Michael J., Wetendorf, Margeaux, Fernandez‐Valdivia, Rodrigo, Jeong, Jae‐Wook, Spencer, Thomas E., Behringer, Richard R., Lydon, John P., DeMayo, Francesco J.

“…The ovarian steroid progesterone, acting through the progesterone receptor (PR), coordinates endometrial epithelial‐stromal cell communication, which is…”
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Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility by Su, Ren-Wei, Strug, Michael R., Jeong, Jae-Wook, Miele, Lucio, Fazleabas, Asgerally T.

“…In mammalian reproduction, implantation is one of the most critical events. Failure of implantation and the subsequent decidualization contribute to more than…”
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Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment by Marquardt, Ryan M., Kim, Tae Hoon, Yoo, Jung‐Yoon, Teasley, Hanna E., Fazleabas, Asgerally T., Young, Steven L., Lessey, Bruce A., Arora, Ripla, Jeong, Jae‐Wook

“…Though endometriosis and infertility are clearly associated, the pathophysiological mechanism remains unclear. Previous work has linked endometrial ARID1A loss…”
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The Association between Type 2 Diabetes Mellitus and Women Cancer: The Epidemiological Evidences and Putative Mechanisms by Joung, Kyong Hye, Ku, Bon Jeong, Jeong, Jae-Wook

“…Type 2 diabetes mellitus (T2DM), a chronic disease increasing rapidly worldwide, is well established as an important risk factor for various types of cancer…”
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Disturbed Cartilage and Joint Homeostasis Resulting From a Loss of Mitogen‐Inducible Gene 6 in a Mouse Model of Joint Dysfunction by Pest, Michael A., Russell, Bailey A., Zhang, Yu‐Wen, Jeong, Jae‐Wook, Beier, Frank

“…Objective Mitogen‐inducible gene 6 (MIG‐6) regulates epidermal growth factor receptor (EGFR) signaling in synovial joint tissues. Whole‐body knockout of the…”
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Interleukin-13 receptor subunit alpha-2 is a target of progesterone receptor and steroid receptor coactivator-1 in the mouse uterus by Marquardt, Ryan M, Lee, Kevin, Kim, Tae Hoon, Lee, Brandon, DeMayo, Francesco J, Jeong, Jae-Wook

“…The endometrium, composed of epithelial and stromal cell compartments, is tightly regulated by the ovarian steroid hormones estrogen (E2) and progesterone (P4)…”
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RBPJ mediates uterine repair in the mouse and is reduced in women with recurrent pregnancy loss by Strug, Michael R., Su, Ren‐Wei, Kim, Tae Hoon, Mauriello, Alessandro, Ticconi, Carlo, Lessey, Bruce A., Young, Steven L., Lim, Jeong Mook, Jeong, Jae‐Wook, Fazleabas, Asgerally T.

“…Unexplained recurrent pregnancy loss (uRPL) is associated with repeated embryo loss and endometrial repair with elevated endometrial expression of inflammatory…”
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Bmp2 Is Critical for the Murine Uterine Decidual Response by Lee, Kevin Y., Jeong, Jae-Wook, Wang, Jinrong, Ma, Lijiang, Martin, James F., Tsai, Sophia Y., Lydon, John P., DeMayo, Francesco J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice by Bellini, Melina, Pest, Michael A, Miranda-Rodrigues, Manuela, Qin, Ling, Jeong, Jae-Wook, Beier, Frank

“…Osteoarthritis (OA) is the most common form of arthritis and characterized by degeneration of the articular cartilage. Mitogen-inducible gene 6 (Mig-6) has…”
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β-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis by Yoo, Jung-Yoon, Ku, Bon Jeong, Kim, Tae Hoon, Il Ahn, Jong, Ahn, Ji Yeon, Yang, Woo Sub, Lim, Jeong Mook, Taketo, Maketo M., Shin, Jung-Ho, Jeong, Jae-Wook

“…Adenomyosis is defined as the presence of ectopic nests of endometrial glands and stroma within the myometrium. Adenomyosis is a common cause of dysmenorrhea,…”
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Progesterone Resistance in PCOS Endometrium: A Microarray Analysis in Clomiphene Citrate-Treated and Artificial Menstrual Cycles by Savaris, Ricardo F, Groll, Jeremy M, Young, Steven L, DeMayo, Franco J, Jeong, Jae-Wook, Hamilton, Amy E, Giudice, Linda C, Lessey, Bruce A

“…The endometrium of women with PCOS is dysfunctional, exhibiting signs of progesterone resistance, consistent with the elevated risk of endometrial cancer and…”
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