Search Results - "Jeon, Ju‐Hong"

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    PI3K pathway in prostate cancer: All resistant roads lead to PI3K by Park, Soonbum, Kim, Young Sik, Kim, Davis Yeon, So, Insuk, Jeon, Ju-Hong

    “…The phosphoinositide 3-kinase (PI3K) pathway integrates multifarious environmental cues to regulate cell survival, growth, and metabolism. Hyperactivation of…”
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    Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer by Kim, Byung Joo, Park, Eun Jung, Lee, Jae Hwa, Jeon, JuHong, Kim, Seon Jeong, So, Insuk

    Published in Cancer science (01-12-2008)
    “…Ca2+ and Mg2+ have a fundamental role in many cellular processes and ion channels are involved in normal physiologic processes and in the pathology of various…”
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    Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease by Hong, Chansik, Seo, Hyemyung, Kwak, Misun, Jeon, Jeha, Jang, Jihoon, Jeong, Eui Man, Myeong, Jongyun, Hwang, Yu Jin, Ha, Kotdaji, Kang, Min Jueng, Lee, Kyu Pil, Yi, Eugene C, Kim, In-Gyu, Jeon, Ju-Hong, Ryu, Hoon, So, Insuk

    Published in Brain (London, England : 1878) (01-10-2015)
    “…Aberrant glutathione or Ca(2+) homeostasis due to oxidative stress is associated with the pathogenesis of neurodegenerative disorders. The Ca(2+)-permeable…”
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    Gαi-mediated TRPC4 activation by polycystin-1 contributes to endothelial function via STAT1 activation by Kwak, Misun, Hong, Chansik, Myeong, Jongyun, Park, Eunice Yon June, Jeon, Ju-Hong, So, Insuk

    Published in Scientific reports (22-02-2018)
    “…Hypertension and aneurysm are frequently associated with autosomal dominant polycystic kidney disease (ADPKD) caused by polycystin-1 (PC1) mutations, which is…”
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    Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers by Myeong, Jongyun, Ko, Juyeon, Kwak, Misun, Kim, Jinsung, Woo, Joohan, Ha, Kotdaji, Hong, Chansik, Yang, Dongki, Kim, Hyun Jin, Jeon, Ju-Hong, So, Insuk

    Published in Scientific reports (14-08-2018)
    “…The transient receptor potential canonical (TRPC) 1 channel is widely distributed in mammalian cells and is involved in many physiological processes. TRPC1 is…”
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    Crystal structure of transglutaminase 2 with GTP complex and amino acid sequence evidence of evolution of GTP binding site by Jang, Tae-Ho, Lee, Dong-Sup, Choi, Kihang, Jeong, Eui Man, Kim, In-Gyu, Kim, Young Whan, Chun, Jung Nyeo, Jeon, Ju-Hong, Park, Hyun Ho

    Published in PloS one (05-09-2014)
    “…Transglutaminase2 (TG2) is a multi-functional protein involved in various cellular processes, including apoptosis, differentiation, wound healing, and…”
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    Altered expression of fucosylation pathway genes is associated with poor prognosis and tumor metastasis in non‑small cell lung cancer by Park, Soonbum, Lim, Jin-Muk, Chun, Jung Nyeo, Lee, Sanghoon, Kim, Tae Min, Kim, Dong-Wan, Kim, Sang-Yeob, Bae, Dong-Jun, Bae, Sang-Mun, So, Insuk, Kim, Hong-Gee, Choi, Ji-Yeob, Jeon, Ju-Hong

    Published in International journal of oncology (01-02-2020)
    “…Fucosylation is a post-translational modification that attaches fucose residues to protein- or lipid-bound oligosaccharides. Certain fucosylation pathway genes…”
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    The interaction domains of transient receptor potential canonical (TRPC)1/4 and TRPC1/5 heteromultimeric channels by Myeong, Jongyun, Ko, Juyeon, Hong, Chansik, Yang, Dongki, Lee, Kyu Pil, Jeon, Ju-hong, So, Insuk

    “…Transient receptor potential canonical (TRPC) family contains a non-selective cation channel, and four TRPC subunits form a functional tetrameric channel…”
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    Structural basis of substrate recognition by a novel thermostable (S)-enantioselective ω-transaminase from Thermomicrobium roseum by Kwon, Sunghark, Lee, Jun Hyuck, Kim, Chang Min, Jang, Hyunseok, Yun, Hyungdon, Jeon, Ju-Hong, So, Insuk, Park, Hyun Ho

    Published in Scientific reports (06-05-2019)
    “…Transaminases catalyze the reversible transfer reaction of an amino group between a primary amine and an α-keto acid, utilizing pyridoxal 5′-phosphate as a…”
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    Transient Receptor Potential Melastatin 7 Channels are Involved in Ginsenoside Rg3‐Induced Apoptosis in Gastric Cancer Cells by Kim, Byung Joo, Nah, Seung‐Yeol, Jeon, JuHong, So, Insuk, Kim, Seon Jeong

    Published in Basic & clinical pharmacology & toxicology (01-10-2011)
    “…:  Ginsenosides play a role in a number of physiological and pharmacological functions in the gastrointestinal tract. The aim of this study was to clarify the…”
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    Cancer Vaccination Drives Nanog-Dependent Evolution of Tumor Cells toward an Immune-Resistant and Stem-like Phenotype by KYUNG HEE NOH, LEE, Young-Ho, JEON, Ju-Hong, TAE HEUNG KANG, MAO, Chih-Ping, WU, T.-C, TAE WOO KIM

    Published in Cancer research (Chicago, Ill.) (01-04-2012)
    “…Due to the exquisite specificity and potency of the immune system, vaccination is in theory the most precise and powerful approach for controlling cancer…”
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    Geraniol suppresses prostate cancer growth through down‐regulation of E2F8 by Lee, Sanghoon, Park, Yu Rang, Kim, Su‐Hwa, Park, Eun‐Jung, Kang, Min Ji, So, Insuk, Chun, Jung Nyeo, Jeon, JuHong

    Published in Cancer medicine (Malden, MA) (01-10-2016)
    “…Geraniol, an acyclic dietary monoterpene, has been found to suppress cancer survival and growth. However, the molecular mechanism underlying the antitumor…”
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    Leptin promotes KATP channel trafficking by AMPK signaling in pancreatic β-cells by Park, Sun-Hyun, Ryu, Shin-Young, Yu, Weon-Jin, Han, Young Eun, Ji, Young-Sun, Oh, Keunhee, Sohn, Jong-Woo, Lim, Ajin, Jeon, Jae-Pyo, Lee, Hyunsu, Lee, Kyu-Hee, Lee, Suk-Ho, Berggren, Per-Olof, Jeon, Ju-Hong, Ho, Won-Kyung

    “…Leptin is a pivotal regulator of energy and glucose homeostasis, and defects in leptin signaling result in obesity and diabetes. The ATP-sensitive potassium (K…”
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    Crizotinib attenuates cancer metastasis by inhibiting TGFβ signaling in non-small cell lung cancer cells by Park, Soonbum, Cho, Eun A, Chun, Jung Nyeo, Lee, Da Young, Lee, Sanghoon, Kim, Mi Yeon, Bae, Sang Mun, Jo, Su In, Lee, So Hee, Park, Hyun Ho, Kim, Tae Min, So, Insuk, Kim, Sang-Yeob, Jeon, Ju-Hong

    Published in Experimental & molecular medicine (01-08-2022)
    “…Crizotinib is a clinically approved tyrosine kinase inhibitor for the treatment of patients with locally advanced or metastatic non-small cell lung cancer…”
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    Transglutaminase 2 mediates transcriptional regulation through BAF250a polyamination by Kim, Hyo-Jun, Lee, Jin-Haeng, Cho, Sung-Yup, Jeon, Ju-Hong, Kim, In-Gyu

    Published in Genes & genomics (01-04-2021)
    “…Background Transglutaminase 2 (TG2) mediates protein modifications by crosslinking or by incorporating polyamine in response to oxidative or DNA-damaging…”
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    TRIP database 2.0: a manually curated information hub for accessing TRP channel interaction network by Shin, Young-Cheul, Shin, Soo-Yong, Chun, Jung Nyeo, Cho, Hyeon Sung, Lim, Jin Muk, Kim, Hong-Gee, So, Insuk, Kwon, Dongseop, Jeon, Ju-Hong

    Published in PloS one (11-10-2012)
    “…Transient receptor potential (TRP) channels are a family of Ca(2+)-permeable cation channels that play a crucial role in biological and disease processes. To…”
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    Isoform- and receptor-specific channel property of canonical transient receptor potential (TRPC)1/4 channels by Kim, Jinsung, Kwak, Misun, Jeon, Jae-Pyo, Myeong, Jongyun, Wie, Jinhong, Hong, Chansik, Kim, Sung-Young, Jeon, Ju-Hong, Kim, Hyun Jin, So, Insuk

    Published in Pflügers Archiv (01-03-2014)
    “…Transient receptor potential canonical (TRPC) 1, the first mammalian homologue of Drosophila trp gene, is distributed widely in mammalian cells and is involved…”
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