Search Results - "Jeon, Jongrye"
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Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors
Published in Cell stem cell (02-07-2015)“…Cell-based therapies to treat retinal degeneration are now being tested in clinical trials. However, it is not known whether the source of stem cells is…”
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2
Neuronal M₃ muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2009)“…The molecular pathways that promote the proliferation and maintenance of pituitary somatotrophs and other cell types of the anterior pituitary gland are not…”
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3
Ontogeny and the possible function of a novel epidermal growth factor‐like repeat domain‐containing protein, NELL2, in the rat brain
Published in Journal of neurochemistry (01-12-2002)“…In this study we investigated the mRNA expression of NELL2, a neural tissue‐specific epidermal growth factor (EGF)‐like repeat domain‐containing protein, in…”
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4
Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
Published in Cancer cell (10-09-2018)“…Personalized cancer therapy targeting somatic mutations in patient tumors is increasingly being incorporated into practice. Other therapeutic vulnerabilities…”
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5
MYCN amplification and ATRX mutations are incompatible in neuroblastoma
Published in Nature communications (14-02-2020)“…Aggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neuroblastoma,…”
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6
A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
Published in Cell metabolism (01-06-2006)“…One of the hallmarks of type 2 diabetes is that pancreatic beta cells fail to release sufficient amounts of insulin in the presence of elevated blood glucose…”
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A Subpopulation of Neuronal M4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors
Published in The Journal of neuroscience (10-02-2010)“…Acetylcholine (ACh) regulates many key functions of the CNS by activating cell surface receptors referred to as muscarinic ACh receptors (M(1)-M(5) mAChRs)…”
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8
A critical role for β cell M 3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
Published in Cell metabolism (01-06-2006)“…One of the hallmarks of type 2 diabetes is that pancreatic β cells fail to release sufficient amounts of insulin in the presence of elevated blood glucose…”
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Journal Article -
9
A Subpopulation of Neuronal M 4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors
Published in The Journal of neuroscience (10-02-2010)“…Acetylcholine (ACh) regulates many key functions of the CNS by activating cell surface receptors referred to as muscarinic ACh receptors (M 1 –M 5 mAChRs)…”
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Journal Article -
10
Involvement of a Subpopulation of Neuronal M 4 Muscarinic Acetylcholine Receptors in the Antipsychotic-like Effects of the M 1 /M 4 Preferring Muscarinic Receptor Agonist Xanomeline
Published in The Journal of neuroscience (20-04-2011)“…Disturbances in central dopaminergic neurotransmission are believed to be centrally involved in the pathogenesis of schizophrenia. Central dopaminergic and…”
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11
Beneficial metabolic effects of M3 muscarinic acetylcholine receptor deficiency
Published in Cell metabolism (01-11-2006)“…Most animal models of obesity and hyperinsulinemia are associated with increased vagal cholinergic activity. The M3 muscarinic acetylcholine receptor subtype…”
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12
Beneficial metabolic effects of M 3 muscarinic acetylcholine receptor deficiency
Published in Cell metabolism (01-11-2006)“…Most animal models of obesity and hyperinsulinemia are associated with increased vagal cholinergic activity. The M 3 muscarinic acetylcholine receptor subtype…”
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13
Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline
Published in The Journal of neuroscience (20-04-2011)“…Disturbances in central dopaminergic neurotransmission are believed to be centrally involved in the pathogenesis of schizophrenia. Central dopaminergic and…”
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14
Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse, and Parkinson’s Disease
Published in ACS chemical neuroscience (15-02-2012)“…The neurotransmitter dopamine plays important roles in modulating cognitive, affective, and motor functions. Dysregulation of dopaminergic neurotransmission is…”
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15
Learning and memory impairments in a congenic C57BL/6 strain of mice that lacks the M 2 muscarinic acetylcholine receptor subtype
Published in Behavioural brain research (26-06-2008)“…The neurotransmitter acetylcholine is an important modulator of cognitive functions including attention, learning, and memory. The actions of acetylcholine are…”
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16
Neuronal M 3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2009)“…The molecular pathways that promote the proliferation and maintenance of pituitary somatotrophs and other cell types of the anterior pituitary gland are not…”
Get full text
Journal Article -
17
Comparative Quantification in Three-Dimensional Cultures reveals Epigenetic Memory and Higher Efficiency Retinogenesis in iPSCs Derived from Differentiated Rod Photoreceptors
Published in Cell stem cell (02-07-2015)“…Cell-based therapies to treat retinal degeneration are now being tested in clinical trials. However, it is not known if the source of stem cells is important…”
Get full text
Journal Article -
18
Learning and memory impairments in a congenic C57BL/6 strain of mice that lacks the M2 muscarinic acetylcholine receptor subtype
Published in Behavioural brain research (26-06-2008)“…The neurotransmitter acetylcholine is an important modulator of cognitive functions including attention, learning, and memory. The actions of acetylcholine are…”
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Journal Article -
19
Metabolic Roles of the M 3 Muscarinic Acetylcholine Receptor Studied with M 3 Receptor Mutant Mice: A Review
Published in Journal of receptors and signal transduction (01-01-2008)Get full text
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Metabolic Roles of the M3 Muscarinic Acetylcholine Receptor Studied with M3 Receptor Mutant Mice: A Review
Published in Journal of receptors and signal transduction (2008)“…The M3 muscarinic acetylcholine (ACh) receptor (M3 mAChR) is expressed in many central and peripheral tissues. It is a prototypic member of the superfamily of…”
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