Search Results - "Jeon, Hyun Yong"
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Association of weekend catch-up sleep ratio and subjective sleep quality with depressive symptoms and suicidal ideation among Korean adolescents
Published in Scientific reports (17-06-2022)“…Circadian misalignment caused by differences in sleep duration between weekends and weekdays may be associated with adolescent mental health and sleep quality…”
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2
DHP23002 as a next generation oral paclitaxel formulation for pancreatic cancer therapy
Published in PloS one (19-11-2019)“…This study aimed to develop a new oral paclitaxel formulation (DHP23002) and to evaluate its absorption and antitumor effects in a pancreatic tumor mouse…”
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3
Phenylbutyrate Ameliorates High-Fat Diet-Induced Obesity via Brown Adipose Tissue Activation
Published in Biological & pharmaceutical bulletin (01-09-2019)“…Obesity, which is characterized by an excessive accumulation of body fat, is one of the critical factors causing metabolic syndrome. Many studies have been…”
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4
Profiling of Clusters of Activity‐Travel Sequences Using a Genetic Algorithm
Published in Geographical analysis (01-07-2021)“…Classification of similar travel behavior is essential for market segmentation research in geography and transportation science. Cluster analysis using…”
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5
Repositioning Trimebutine Maleate as a Cancer Treatment Targeting Ovarian Cancer Stem Cells
Published in Cells (Basel, Switzerland) (16-04-2021)“…The overall five-year survival rate for late-stage patients of ovarian cancer is below 29% due to disease recurrence and drug resistance. Cancer stem cells…”
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6
Intensive Motion Style Acupuncture Treatment (MSAT) Is Effective for Patients with Acute Whiplash Injury: A Randomized Controlled Trial
Published in Journal of clinical medicine (02-07-2020)“…In this single-center, parallel, randomized controlled trial, we aim to examine the effects and safety of motion style acupuncture treatment (MSAT; a…”
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Correction: Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue
Published in Experimental & molecular medicine (01-06-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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8
In vivo monitoring of transfected DNA, gene expression kinetics, and cellular immune responses in mice immunized with a human NIS gene-expressing plasmid
Published in International journal of immunopathology and pharmacology (01-12-2016)“…In assessing the effectiveness of DNA vaccines, it is important to monitor: (1) the kinetics of target gene expression in vivo; and (2) the movement of cells…”
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9
Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides
Published in Open biology (01-10-2012)“…Alternative splicing of the pyruvate kinase M gene involves a choice between mutually exclusive exons 9 and 10. Use of exon 10 to generate the M2 isoform is…”
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10
Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression
Published in Nature communications (09-07-2020)“…While most monogenic diseases are caused by loss or reduction of protein function, the need for technologies that can selectively increase levels of protein in…”
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11
ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth
Published in Cancer research (Chicago, Ill.) (01-03-2022)“…The M2 pyruvate kinase (PKM2) isoform is upregulated in most cancers and plays a crucial role in regulation of the Warburg effect, which is characterized by…”
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12
Regulation of systemic energy homeostasis by serotonin in adipose tissues
Published in Nature communications (13-04-2015)“…Central serotonin (5-HT) is an anorexigenic neurotransmitter in the brain. However, accumulating evidence suggests peripheral 5-HT may affect organismal energy…”
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13
Targeting Peroxisome Proliferator-Activated Receptor Delta (PPARδ): A Medicinal Chemistry Perspective
Published in Journal of medicinal chemistry (24-09-2020)“…One of the three subtypes of the peroxisome proliferator-activated receptor (PPAR) functioning as a transcription factor is the PPARβ or PPARδ. PPARδ is…”
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14
Visualization of Hypoxia-Inducible Factor-1 Transcriptional Activation in C6 Glioma Using Luciferase and Sodium Iodide Symporter Genes
Published in Journal of Nuclear Medicine (01-09-2008)“…Hypoxia-inducible factor-1 (HIF-1) is a transcription factor of hypoxic response in cancer cells and is associated with tumor progression, angiogenesis,…”
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15
Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling
Published in Molecular cancer (21-11-2016)“…Background Triple-negative breast cancer (TNBC) has a high risk of relapse and there are few chemotherapy options. Although 5-hydroxytryptamine (5-HT,…”
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16
Synergistic tumoricidal effect of combined hMUC1 vaccination and hNIS radioiodine gene therapy
Published in Molecular cancer therapeutics (01-07-2008)“…We examined the merits of combinatorial hMUC1 vaccination and hNIS radioiodine gene therapy and evaluated its tumoricidal effects in an animal tumor model…”
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17
Human sodium iodide symporter gene adjunctive radiotherapy to enhance the preventive effect of hMUC1 DNA vaccine
Published in International journal of cancer (01-10-2007)“…We demonstrate the use of combination therapy to overcome the limitations of cancer DNA vaccines by adding radioiodine gene therapy in an animal cancer model…”
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18
Immune response to firefly luciferase as a naked DNA
Published in Cancer biology & therapy (01-05-2007)“…Firefly luciferase (Fluc) has been widely used as a reporter gene. The aim of this study was to investigate immune response to luciferase protein after an…”
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19
Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-2009)“…Astrocyte-elevated gene-1 (AEG-1) expression is increased in multiple cancers and plays a central role in Ha-ras-mediated oncogenesis through the…”
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20
PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels
Published in Diabetes (New York, N.Y.) (01-10-2018)“…In fasting or diabetes, gluconeogenic genes are transcriptionally activated by glucagon stimulation of the cAMP-protein kinase A (PKA)-CREB signaling pathway…”
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