Search Results - "Jeon, Hong Ryeol"
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Mutagenic Assessment of Olmesartan Cilexetil by Bacterial Mutation Assay
Published in Toxicological research (Seoul) (2013)“…Hypertension is a serious health problem due to high frequency and concomitant other diseases including cardiovascular and renal dysfunction. Olmesartan…”
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2
Discovery of olmesartan hexetil: A new potential prodrug of olmesartan
Published in Bioorganic & medicinal chemistry letters (01-03-2013)“…Synthesis of a new ester prodrug of olmesartan, olmesartan hexetil (1), is described. It is in vitro stabilities and in vivo pharmacokinetics (PK) were…”
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3
Novel amides and esters prodrugs of olmesartan: Synthesis, bioconversion, and pharmacokinetic evaluation
Published in Bioorganic & medicinal chemistry letters (01-10-2010)“…Compound IIa was found to be well absorbed from rat gastrointestinal tract and rapidly converted into olmesartan. After oral administration of IIa, the C max…”
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4
Solid dispersion formulations of megestrol acetate with copovidone for enhanced dissolution and oral bioavailability
Published in Archives of pharmacal research (2011)“…In order to enhance the dissolution profile and oral bioavailability of megestrol acetate (MA), solid dispersions of MA (MASDs) were formulated with copovidone…”
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5
Design, synthesis, bioconversion, and pharmacokinetics evaluation of new ester prodrugs of olmesartan
Published in European journal of medicinal chemistry (01-09-2011)“…Synthesis of new ester prodrugs of olmesartan is described. Their in vitro stabilities in simulated gastric juice, rat plasma, and rat liver microsomes were…”
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Mutagenic Assessment of Olmesartan Cilexetil by Bacterial Mutation Assay
Published in Toxicological research (Seoul) (01-09-2013)“…Hypertension is a serious health problem due to high frequency and concomitant other diseases including cardiovascular and renal dysfunction. Olmesartan…”
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Journal Article -
7
Immediate release tablet formulation of varenicline salicylate and comparative pharmacokinetic study in human volunteers
Published in Drug design, development and therapy (01-01-2018)“…To develop an immediate release-type tablet containing varenicline salicylate (VRC-S), a smoking cessation agent, formulation and stability studies were…”
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