Search Results - "Jentsch, Marcel"

p53 dynamics in single cells are temperature-sensitive by Jentsch, Marcel, Snyder, Petra, Sheng, Caibin, Cristiano, Elena, Loewer, Alexander

“…Cells need to preserve genome integrity despite varying cellular and physical states. p53, the guardian of the genome, plays a crucial role in the cellular…”
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Cell‐specific responses to the cytokine TGFβ are determined by variability in protein levels by Strasen, Jette, Sarma, Uddipan, Jentsch, Marcel, Bohn, Stefan, Sheng, Caibin, Horbelt, Daniel, Knaus, Petra, Legewie, Stefan, Loewer, Alexander

“…The cytokine TGFβ provides important information during embryonic development, adult tissue homeostasis, and regeneration. Alterations in the cellular response…”
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PCNA-Mediated Degradation of p21 Coordinates the DNA Damage Response and Cell Cycle Regulation in Individual Cells by Sheng, Caibin, Mendler, Isabella-Hilda, Rieke, Sara, Snyder, Petra, Jentsch, Marcel, Friedrich, Dhana, Drossel, Barbara, Loewer, Alexander

“…To enable reliable cell fate decisions, mammalian cells need to adjust their responses to dynamically changing internal states by rewiring the corresponding…”
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Creating cloud platforms for supporting FAIR data management in biomedical research projects. [version 3; peer review: 1 approved, 1 approved with reservations] by Jentsch, Marcel, Schneider-Lunitz, Valentin, Taron, Ulrike, Braun, Martin, Ishaque, Naveed, Wagener, Harald, Conrad, Christian, Twardziok, Sven

“…Biomedical research projects are becoming increasingly complex and require technological solutions that support all phases of the data lifecycle and…”
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Creating cloud platforms for supporting FAIR data management in biomedical research projects. [version 1; peer review: awaiting peer review] by Jentsch, Marcel, Schneider-Lunitz, Valentin, Taron, Ulrike, Braun, Martin, Ishaque, Naveed, Wagener, Harald, Conrad, Christian, Twardziok, Sven

“…Biomedical research projects are becoming increasingly complex and require technological solutions that support all phases of the data lifecycle and…”
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Effects of urban living environments on mental health in adults by Xu, Jiayuan, Liu, Nana, Polemiti, Elli, Garcia-Mondragon, Liliana, Tang, Jie, Liu, Xiaoxuan, Lett, Tristram, Yu, Le, Nöthen, Markus M., Feng, Jianfeng, Yu, Chunshui, Marquand, Andre, Schumann, Gunter

“…Urban-living individuals are exposed to many environmental factors that may combine and interact to influence mental health. While individual factors of an…”
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Creating cloud platforms for supporting FAIR data management in biomedical research projects. [version 2; peer review: 1 approved, 1 approved with reservations] by Jentsch, Marcel, Schneider-Lunitz, Valentin, Taron, Ulrike, Braun, Martin, Ishaque, Naveed, Wagener, Harald, Conrad, Christian, Twardziok, Sven

“…Biomedical research projects are becoming increasingly complex and require technological solutions that support all phases of the data lifecycle and…”
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Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience: A Review by Schumann, Gunter, Andreassen, Ole A, Banaschewski, Tobias, Calhoun, Vince D, Clinton, Nicholas, Desrivieres, Sylvane, Brandlistuen, Ragnhild Eek, Feng, Jianfeng, Hese, Soeren, Hitchen, Esther, Hoffmann, Per, Jia, Tianye, Jirsa, Viktor, Marquand, Andre F, Nees, Frauke, Nöthen, Markus M, Novarino, Gaia, Polemiti, Elli, Ralser, Markus, Rapp, Michael, Schepanski, Kerstin, Schikowski, Tamara, Slater, Mel, Sommer, Peter, Stahl, Bernd Carsten, Thompson, Paul M, Twardziok, Sven, van der Meer, Dennis, Walter, Henrik, Westlye, Lars

“…Climate change, pollution, urbanization, socioeconomic inequality, and psychosocial effects of the COVID-19 pandemic have caused massive changes in…”
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Algorithms for differential splicing detection using exon arrays: a comparative assessment by Zimmermann, Karin, Jentsch, Marcel, Rasche, Axel, Hummel, Michael, Leser, Ulf

“…The analysis of differential splicing (DS) is crucial for understanding physiological processes in cells and organs. In particular, aberrant transcripts are…”
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A protocol for data harmonization in large cohorts by Neidhart, Maja, Kjelkenes, Rikka, Jansone, Karina, Rehák Bučková, Barbora, Holz, Nathalie, Nees, Frauke, Walter, Henrik, Schumann, Gunter, Rapp, Michael A., Banaschewski, Tobias, Schwarz, Emanuel, Marquand, Andre

“…This Comment presents a high-level protocol for data harmonization within large cohorts, in which it postulates four main steps including (1) expert review,…”
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Multi-omics analyses of the environMENTAL project provide insights into mental health and disease by Desrivières, Sylvane, Miller, Abigail, Mathey, Carina M., Yu, Xinyang, Chen, Di, Agunbiade, Kofoworola, Heilmann-Heimbach, Stefanie, Forstner, Andreas J., Schumann, Gunter, Hoffmann, Per, Nöthen, Markus M.

“…Integrative analyses that incorporate different levels of ‘-omics’ data represent a powerful tool for deciphering the biological mechanisms that underlie…”
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Rethinking ethics in interdisciplinary and big data-driven neuroscience projects by Stahl, Bernd Carsten, Ogoh, George, Schumann, Gunter, Walter, Henrik

“…The focus of much of contemporary research ethics is on compliance with established protocols. However, large data-driven neuroscience research raises new…”
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Large-scale population data enrichment in mental health research by Nees, Frauke, Renner, Paul, Holz, Nathalie E., Polemiti, Elli, Siehl, Sebastian, Hese, Sören, Schepanski, Kerstin, Schumann, Gunter

“…This Comment explores new approaches to enrich large-scale population data, including incorporating macro-environmental and digital health measures…”
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Detecting hierarchical structure in molecular characteristics of disease using transitive approximations of directed graphs by Jacob, Juby, Jentsch, Marcel, Kostka, Dennis, Bentink, Stefan, Spang, Rainer

“…Motivation: Molecular diagnostics aims at classifying diseases into clinically relevant sub-entities based on molecular characteristics. Typically, the…”
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