Search Results - "Jensenius, J C"

Lectin complement pathway proteins in healthy individuals by Troldborg, A., Hansen, A., Hansen, S. W. K., Jensenius, J. C., Stengaard‐Pedersen, K., Thiel, S.

“…Summary Since the discovery of the lectin pathway of complement activation, numerous clinical cohorts have been examined for one or more proteins, with the…”
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Mannan‐binding lectin (MBL)‐associated serine protease‐1 (MASP‐1), a serine protease associated with humoral pattern‐recognition molecules: normal and acute‐phase levels in serum and stoichiometry of lectin pathway components by Thiel, S., Jensen, L., Degn, S. E., Nielsen, H. J., Gál, P., Dobó, J., Jensenius, J. C.

“…Summary The pattern‐recognition molecules mannan‐binding lectin (MBL) and the three ficolins circulate in blood in complexes with MBL‐associated serine…”
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Collectin liver 1 and collectin kidney 1 and other complement‐associated pattern recognition molecules in systemic lupus erythematosus by Troldborg, A., Thiel, S., Jensen, L., Hansen, S., Laska, M. J., Deleuran, B., Jensenius, J. C., Stengaard‐Pedersen, K.

“…Summary The objective of this study was to explore the involvement of collectin liver 1 (CL‐L1) and collectin kidney 1 (CL‐K1) and other pattern recognition…”
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Oligomerization of Mannan‐binding Lectin Dictates Binding Properties and Complement Activation by Kjaer, T. R., Jensen, L., Hansen, A., Dani, R., Jensenius, J. C., Dobó, J., Gál, P., Thiel, S.

“…The complement system is a part of the innate immune system and is involved in recognition and clearance of pathogens and altered‐self structures. The lectin…”
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Clinical manifestations of mannan-binding lectin deficiency by Thiel, S., Frederiksen, P.D., Jensenius, J.C.

“…Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency…”
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M‐ficolin levels are associated with the occurrence of severe infections in patients with haematological cancer undergoing chemotherapy by Ameye, L., Paesmans, M., Thiel, S., Jensenius, J. C., Aoun, M.

“…Summary The pattern recognition molecules H‐ficolin, L‐ficolin and M‐ficolin bind to micro‐organisms. They activate the lectin pathway of complement through…”
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Mannan‐Binding Lectin Recognizes Structures on Ischaemic Reperfused Mouse Kidneys and is Implicated in Tissue Injury by Møller‐Kristensen, M., Wang, W., Ruseva, M., Thiel, S., Nielsen, S., Takahashi, K., Shi, L., Ezekowitz, A., Jensenius, J. C., Gadjeva, M.

“…Organ damage as a consequence of ischaemia and reperfusion (I/R) is a major clinical problem in an acute renal failure and transplantation. Ligands on surfaces…”
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Preparation and comparison of cytotoxic complexes formed between oleic acid and either bovine or human α-lactalbumin by Brinkmann, C R, Thiel, S, Larsen, M K, Petersen, T E, Jensenius, J C, Heegaard, C W

“…α-Lactalbumin is a ubiquitous calcium-binding milk protein with a well-characterized function in regulating the synthesis of lactose. An entirely different…”
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An assay for the mannan-binding lectin pathway of complement activation by Petersen, S.V, Thiel, S, Jensen, L, Steffensen, R, Jensenius, J.C

“…The mannan-binding lectin (MBL) pathway of complement activation has been established as the third pathway of complement activation. MBL is a…”
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Levels of lectin pathway proteins in plasma and synovial fluid of rheumatoid arthritis and osteoarthritis by Ammitzboll, C. G., Thiel, S., Ellingsen, T., Deleuran, B., Jorgensen, Anette, Jensenius, J. C., Stengaard-Pedersen, K.

“…The innate immune system contributes to the development of rheumatoid arthritis (RA). A potent contributor to such processes is the complement system. The…”
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Hormonal regulation of mannan‐binding lectin synthesis in hepatocytes by Sørensen, C. M., Hansen, T. K., Steffensen, R., Jensenius, J. C., Thiel, S.

“…Summary Activation of the complement system via the plasma protein mannan‐binding lectin (MBL) provides a first line of defence against infections. The plasma…”
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H-ficolin serum concentration and susceptibility to fever and neutropenia in paediatric cancer patients by Schlapbach, L.J, Aebi, C, Hansen, A.G, Hirt, A, Jensenius, J.C, Ammann, R.A

“…H-ficolin (Hakata antigen, ficolin-3) activates the lectin pathway of complement similar to mannose-binding lectin. However, its impact on susceptibility to…”
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Mannan‐binding lectin modulates the response to HSV‐2 infection by GADJEVA, M., PALUDAN, S. R., THIEL, S., SLAVOV, V., RUSEVA, M., ERIKSSON, K., LÖWHAGEN, G.‐B., SHI, L., TAKAHASHI, K., EZEKOWITZ, A., JENSENIUS, J. C.

“…SUMMARY Viruses have developed numerous strategies to escape recognition by the immune system. However, some viruses such as herpes simplex virus‐2 (HSV‐2) are…”
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Detection of structural gene mutations and promoter polymorphisms in the mannan-binding lectin (MBL) gene by polymerase chain reaction with sequence-specific primers by Steffensen, Rudi, Thiel, Steffen, Varming, Kim, Jersild, Casper, Jensenius, Jens Christian

“…This study describes a new approach to the determination of all known mannan-binding lectin (MBL) mutations. The distribution of known variants of the MBL gene…”
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Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms by Thiel, S, Steffensen, R, Christensen, I J, Ip, W K, Lau, Y L, Reason, I J M, Eiberg, H, Gadjeva, M, Ruseva, M, Jensenius, J C

“…Mannan-binding lectin (MBL) and ficolins distinguish between self, non-self and altered-self by recognizing patterns of ligands on the surface of…”
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The mannan-binding lectin pathway of complement activation: biology and disease association by Vang Petersen, Steen, Thiel, Steffen, Jensenius, Jens Christian

“…Mannan-binding lectin (MBL) is a plasma protein found in association with several serine proteases (MASPs) forming the MBL complex. MBL recognises carbohydrate…”
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Deficiency of the mannan‐binding lectin pathway of complement and poor outcome in cystic fibrosis: bacterial colonization may be decisive for a relationship by Carlsson, M., Sjöholm, A. G., Eriksson, L., Thiel, S., Jensenius, J. C., Segelmark, M., Truedsson, L.

“…Summary In cystic fibrosis (CF) prognosis concerning lung damage development is highly variable and difficult to predict. Mannan‐binding lectin (MBL)…”
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Influence of major surgery on the mannan‐binding lectin pathway of innate immunity by Ytting, H., Christensen, I. J., Basse, L., Lykke, J., Thiel, S., Jensenius, J. C., Nielsen, H. J.

“…Summary The mannan‐binding lectin (MBL) pathway of complement activation is important in host defence against pathogens and possibly against cancer. We…”
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Proteolytic Activities of Two Types of Mannose-Binding Lectin-Associated Serine Protease by Matsushita, Misao, Thiel, Steffen, Jensenius, Jens C, Terai, Itaru, Fujita, Teizo

“…Mannose (or mannan)-binding lectin (MBL) is an oligomeric serum lectin that plays a role in innate immunity by activating the complement system. In human, two…”
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Mannan-binding lectin MBL2 gene polymorphism in chronic hepatitis C: association with the severity of liver fibrosis and response to interferon therapy by Alves Pedroso, M.L, Boldt, A.B.W, Pereira-Ferrari, L, Steffensen, R, Strauss, E, Jensenius, J.C, Ioshii, S.O, Messias-Reason, I

“…Hepatitis C virus (HCV) is a major cause of hepatic disease and of liver transplantation worldwide. Mannan-binding lectin (MBL), encoded by the MBL2 gene, can…”
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