Search Results - "Jensen, Simon K"

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses by Holm, Christian K., Rahbek, Stine H., Gad, Hans Henrik, Bak, Rasmus O., Jakobsen, Martin R., Jiang, Zhaozaho, Hansen, Anne Louise, Jensen, Simon K., Sun, Chenglong, Thomsen, Martin K., Laustsen, Anders, Nielsen, Camilla G., Severinsen, Kasper, Xiong, Yingluo, Burdette, Dara L., Hornung, Veit, Lebbink, Robert Jan, Duch, Mogens, Fitzgerald, Katherine A., Bahrami, Shervin, Mikkelsen, Jakob Giehm, Hartmann, Rune, Paludan, Søren R.

“…Stimulator of interferon genes (STING) is known be involved in control of DNA viruses but has an unexplored role in control of RNA viruses. During infection…”
Get full text

Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized controlled trial by Sandsdal, Rasmus M, Juhl, Christian R, Jensen, Simon B K, Lundgren, Julie R, Janus, Charlotte, Blond, Martin B, Rosenkilde, Mads, Bogh, Adrian F, Gliemann, Lasse, Jensen, Jens-Erik B, Antoniades, Charalambos, Stallknecht, Bente M, Holst, Jens J, Madsbad, Sten, Torekov, Signe S

“…Identifying and reducing cardiometabolic risks driven by obesity remains a healthcare challenge. The metabolic syndrome is associated with abdominal obesity…”
Get full text

Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined by Lundgren, Julie R, Janus, Charlotte, Jensen, Simon B.K, Juhl, Christian R, Olsen, Lisa M, Christensen, Rasmus M, Svane, Maria S, Bandholm, Thomas, Bojsen-Møller, Kirstine N, Blond, Martin B, Jensen, Jens-Erik B, Stallknecht, Bente M, Holst, Jens J, Madsbad, Sten, Torekov, Signe S

“…In this trial, adults with obesity without diabetes were randomly assigned, after an 8-week low-calorie diet, to 1 year of placebo, an exercise program,…”
Get full text

Interleukin-21 receptor signalling is important for innate immune protection against HSV-2 infections by Kratholm, Sine K, Iversen, Marie B, Reinert, Line, Jensen, Simon K, Hokland, Marianne, Andersen, Thomas, Rankin, Andrew, Young, Deborah, Frische, Sebastian, Paludan, Søren R, Holm, Christian K

“…Interleukin (IL) -21 is produced by Natural Killer T (NKT) cells and CD4(+) T cells and is produced in response to virus infections, where IL-21 has been shown…”
Get full text

Recovery of kidney function after acute kidney disease—a multi-cohort analysis by Sawhney, Simon, Ball, William, Bell, Samira, Black, Corri, Christiansen, Christian F, Heide-Jørgensen, Uffe, Jensen, Simon K, Lambourg, Emilie, Ronksley, Paul E, Tan, Zhi, Tonelli, Marcello, James, Matthew T

“…ABSTRACT Background There are no consensus definitions for evaluating kidney function recovery after acute kidney injury (AKI) and acute kidney disease (AKD),…”
Get full text

Risk factor analysis for a rapid progression of chronic kidney disease by Vestergaard, Anne H S, Jensen, Simon K, Heide-Jørgensen, Uffe, Frederiksen, Line E, Birn, Henrik, Jarbøl, Dorte E, Søndergaard, Jens, Persson, Frederik, Thomsen, Reimar W, Christiansen, Christian F

“…ABSTRACT Background Chronic kidney disease (CKD) is a growing global health concern. Identifying individuals in routine clinical care with new-onset CKD at…”
Get full text

Acute Kidney Injury Duration and 20-Year Risks of CKD and Cardiovascular Disease by Jensen, Simon K., Heide-Jørgensen, Uffe, Gammelager, Henrik, Birn, Henrik, Christiansen, Christian F.

“…Acute kidney injury (AKI) is associated with chronic kidney disease (CKD) and cardiovascular disease (CVD); however, it is unclear whether AKI duration affects…”
Get full text

Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA by Chiliveru, Srikanth, Rahbek, Stine H, Jensen, Simon K, Jørgensen, Sofie E, Nissen, Sara K, Christiansen, Stig H, Mogensen, Trine H, Jakobsen, Martin R, Iversen, Lars, Johansen, Claus, Paludan, Søren R

“…Keratinocytes are involved in protecting the body from infections and environmental challenges, but also in inflammatory conditions like psoriasis. DNA has…”
Get full text

Defining Baseline Creatinine for Identification of AKI in Population-Based Laboratory Databases: A Danish Nationwide Cohort Study by Graversen, Henriette V, Jensen, Simon K, Vestergaard, Søren V, Heide-Jørgensen, Uffe, Christiansen, Christian F

“…The baseline creatinine level is central in the Kidney Disease Improving Global Outcomes (KDIGO) criteria of AKI, but baseline creatinine is often…”
Get full text

Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined. Reply by Jensen, Simon B K, Torekov, Signe S

Get full text

Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial by Andersen, Emil, Juhl, Christian R, Kjøller, Emma T, Lundgren, Julie R, Janus, Charlotte, Dehestani, Yasmin, Saupstad, Marte, Ingerslev, Lars R, Duun, Olivia M, Jensen, Simon B K, Holst, Jens J, Stallknecht, Bente M, Madsbad, Sten, Torekov, Signe S, Barrès, Romain

“…Abstract STUDY QUESTION Does diet-induced weight loss improve semen parameters, and are these possible improvements maintained with sustained weight loss?…”
Get full text

Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function by Jensen, Simon B. K., Juhl, Christian R., Janus, Charlotte, Lundgren, Julie R., Martinussen, Christoffer, Wiingaard, Christoffer, Knudsen, Cecilie, Frikke‐Schmidt, Ruth, Stallknecht, Bente M., Holst, Jens J., Madsbad, Sten, Torekov, Signe S.

“…Objective The aim of this study was to investigate glucose tolerance, glucagon response, and beta cell function during a 1‐year maintenance period with either…”
Get full text

Insufficient sleep predicts poor weight loss maintenance after 1 year by Bogh, Adrian F, Jensen, Simon B K, Juhl, Christian R, Janus, Charlotte, Sandsdal, Rasmus M, Lundgren, Julie R, Noer, Mikkel H, Vu, Nhu Q, Fiorenza, Matteo, Stallknecht, Bente M, Holst, Jens J, Madsbad, Sten, Torekov, Signe S

“…Abstract Study Objectives Insufficient sleep may attenuate weight loss, but the role of sleep in weight loss maintenance is unknown. Since weight regain after…”
Get full text

Weight-loss maintenance is accompanied by interconnected alterations in circulating FGF21-adiponectin-leptin and bioactive sphingolipids by Fiorenza, Matteo, Checa, Antonio, Sandsdal, Rasmus M., Jensen, Simon B.K., Juhl, Christian R., Noer, Mikkel H., Bogh, Nicolai P., Lundgren, Julie R., Janus, Charlotte, Stallknecht, Bente M., Holst, Jens Juul, Madsbad, Sten, Wheelock, Craig E., Torekov, Signe S.

“…Weight loss is often followed by weight regain. Characterizing endocrine alterations accompanying weight reduction and regain may disentangle the complex…”
Get full text

Oral Anticoagulant Therapy and Risk of Kidney Disease: A Nationwide Cohort Study: TH-OR04 by Vestergaard, Ane Emilie F., Jensen, Simon K., Heide-Jørgensen, Uffe, Adelborg, Kasper, Birn, Henrik, Carrero, Juan J., Christiansen, Christian F.

Get full text

NKT cell activation by local α-galactosylceramide administration decreases susceptibility to HSV-2 infection by Iversen, Marie Beck, Jensen, Simon Kok, Hansen, Anne Louise, Winther, Henriette, Issazadeh-Navikas, Shohreh, Reinert, Line Sinnathamby, Holm, Christian Kanstrup

“…Abstract NKT cells are a subgroup of T cells, which express a restricted TCR repertoire and are critical for the innate immune responses to viral infections…”
Get full text

Weight Loss Induces Changes in Vitamin D Status in Women with Obesity but not in Men: a Randomized Clinical Trial by Holt, Rune, Holt, Joachim, Jorsal, Mads Joon, Sandsdal, Rasmus M, Jensen, Simon B K, Byberg, Sarah, Juhl, Christian Rimer, Lundgren, Julie Rehné, Janus, Charlotte, Stallknecht, Bente Merete, Holst, Jens Juul, Juul, Anders, Madsbad, Sten, Jensen, Martin Blomberg, Torekov, Signe Sørensen

“…Abstract Context Obesity is associated with low vitamin D and recent studies have suggested a difference in vitamin D metabolism between females and males…”
Get full text

Interleukin-21 Receptor Signalling Is Important for Innate Immune Protection against HSV-2 Infections: e81790 by Kratholm, Sine K, Iversen, Marie B, Reinert, Line, Jensen, Simon K, Hokland, Marianne, Andersen, Thomas, Rankin, Andrew, Young, Deborah, Frische, Sebastian, Paludan, Soeren R

“…Interleukin (IL) -21 is produced by Natural Killer T (NKT) cells and CD4+ T cells and is produced in response to virus infections, where IL-21 has been shown…”
Get full text