Search Results - "Jensen, N."

Interpreting the protein language using proteomics by Jensen, Ole N

“…Post-translational modifications define the functional and structural plasticity of proteins in archaea, prokaryotes and eukaryotes. Multi-site protein…”
Get full text

Modification-specific proteomics: Strategies for characterization of post-translational modifications using enrichment techniques by Zhao, Yingming, Jensen, Ole N

“…More than 300 different types of protein post-translational modifications (PTMs) have been described, many of which are known to have pivotal roles in cellular…”
Get full text

FlashPack: Fast and Simple Preparation of Ultrahigh-performance Capillary Columns for LC-MS[S] by Kovalchuk, Sergey I., Jensen, Ole N., Rogowska-Wrzesinska, Adelina

“…FlashPack is a fast and simple protocol for capillary column packing. It is developed for the classical 100 bars pressure bomb setup and ultrahigh sorbent…”
Get full text

Comparing efficacy and safety of fibrinogen concentrate to cryoprecipitate in bleeding patients: a systematic review by Jensen, N. H. L., Stensballe, J., Afshari, A.

“…Background Bleeding is associated with the depletion of fibrinogen, thus increasing the risk of coagulopathy, further bleeding and transfusion requirements…”
Get full text

Two distinct modes for propagation of histone PTMs across the cell cycle by Alabert, Constance, Barth, Teresa K, Reverón-Gómez, Nazaret, Sidoli, Simone, Schmidt, Andreas, Jensen, Ole N, Imhof, Axel, Groth, Anja

“…Epigenetic states defined by chromatin can be maintained through mitotic cell division. However, it remains unknown how histone-based information is…”
Get full text

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas by Mohammad, Faizaan, Weissmann, Simon, Leblanc, Benjamin, Pandey, Deo P, Højfeldt, Jonas W, Comet, Itys, Zheng, Chunqin, Johansen, Jens Vilstrup, Rapin, Nicolas, Porse, Bo T, Tvardovskiy, Andrey, Jensen, Ole N, Olaciregui, Nagore G, Lavarino, Cinzia, Suñol, Mariona, de Torres, Carmen, Mora, Jaume, Carcaboso, Angel M, Helin, Kristian

“…Although mutant H3K27M histones inhibit PRC2 in diffuse intrinsic pontine gliomas, these tumors exhibit significant amounts of PRC2 activity. The repression of…”
Get full text

Misaligned protoplanetary disks in a young binary star system by Jensen, Eric L. N., Akeson, Rachel

“…Observations show that one or both of the protoplanetary disks in the young binary system HK Tauri are significantly inclined to the binary orbital plane,…”
Get full text

Analytical strategies for phosphoproteomics by Thingholm, Tine E, Jensen, Ole N, Larsen, Martin R

“…Protein phosphorylation is a key regulator of cellular signaling pathways. It is involved in most cellular events in which the complex interplay between…”
Get full text

Transcription Factor Cooperativity in Early Adipogenic Hotspots and Super-Enhancers by Siersbæk, Rasmus, Rabiee, Atefeh, Nielsen, Ronni, Sidoli, Simone, Traynor, Sofie, Loft, Anne, Poulsen, Lars La Cour, Rogowska-Wrzesinska, Adelina, Jensen, Ole N., Mandrup, Susanne

“…It is becoming increasingly clear that transcription factors operate in complex networks through thousands of genomic binding sites, many of which bind several…”
Get full text

Incidence of and Risk Factors for Sick Sinus Syndrome in the General Population by Jensen, Paul N., MPH, Gronroos, Noelle N., MA, MPH, Chen, Lin Y., MD, MS, Folsom, Aaron R., MD, MPH, deFilippi, Chris, MD, Heckbert, Susan R., MD, PhD, Alonso, Alvaro, MD, PhD

“…Abstract Background Little is known about the incidence of and risk factors for sick sinus syndrome (SSS), a common indication for pacemaker implantation…”
Get full text

Quantitative Assessment of In-solution Digestion Efficiency Identifies Optimal Protocols for Unbiased Protein Analysis by León, Ileana R., Schwämmle, Veit, Jensen, Ole N., Sprenger, Richard R.

“…The majority of mass spectrometry-based protein quantification studies uses peptide-centric analytical methods and thus strongly relies on efficient and…”
Get full text

Transcription shapes genome-wide histone acetylation patterns by Martin, Benjamin J. E., Brind’Amour, Julie, Kuzmin, Anastasia, Jensen, Kristoffer N., Liu, Zhen Cheng, Lorincz, Matthew, Howe, LeAnn J.

“…Histone acetylation is a ubiquitous hallmark of transcription, but whether the link between histone acetylation and transcription is causal or consequential…”
Get full text

First-principles study of luminescence in Ce-doped inorganic scintillators by Canning, A., Chaudhry, A., Boutchko, R., Grønbech-Jensen, N.

Get full text

The COVID-19 pandemic underscores the need for an equity-focused global health agenda by Jensen, N., Kelly, A. H., Avendano, M.

“…Over the past few months, COVID-19 has ravaged health systems and economies in countries across the world. While many would argue that a pandemic of…”
Get full text

Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity by Hammer, C, Stepniak, B, Schneider, A, Papiol, S, Tantra, M, Begemann, M, Sirén, A-L, Pardo, L A, Sperling, S, Mohd Jofrry, S, Gurvich, A, Jensen, N, Ostmeier, K, Lühder, F, Probst, C, Martens, H, Gillis, M, Saher, G, Assogna, F, Spalletta, G, Stöcker, W, Schulz, T F, Nave, K-A, Ehrenreich, H

“…In 2007, a multifaceted syndrome, associated with anti-NMDA receptor autoantibodies (NMDAR-AB) of immunoglobulin-G isotype, has been described, which variably…”
Get full text

Organic matter processing by microbial communities throughout the Atlantic water column as revealed by metaproteomics by Bergauer, Kristin, Fernandez-Guerra, Antonio, Garcia, Juan A. L., Sprenger, Richard R., Stepanauskas, Ramunas, Pachiadaki, Maria G., Jensen, Ole N., Herndl, Gerhard J.

“…The phylogenetic composition of the heterotrophic microbial community is depth stratified in the oceanic water column down to abyssopelagic layers. In the…”
Get full text

Proteomic analysis of post-translational modifications by Mann, Matthias, Jensen, Ole N

“…Post-translational modifications modulate the activity of most eukaryote proteins. Analysis of these modifications presents formidable challenges but their…”
Get full text

Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study by Lemaitre, Rozenn N, Yu, Chaoyu, Hoofnagle, Andrew, Hari, Nair, Jensen, Paul N, Fretts, Amanda M, Umans, Jason G, Howard, Barbara V, Sitlani, Colleen M, Siscovick, David S, King, Irena B, Sotoodehnia, Nona, McKnight, Barbara

“…Experimental studies suggest ceramides may play a role in insulin resistance. However, the relationships of circulating ceramides and related sphingolipids…”
Get full text

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation by Weissmann, Simon, Cloos, Paul A, Sidoli, Simone, Jensen, Ole N, Pollard, Steven, Helin, Kristian

“…Oligodendrogliomas are brain tumors accounting for approximately 10% of all central nervous system cancers. CIC is a transcription factor that is mutated in…”
Get full text

A national survey of practical airway training in UK anaesthetic departments. Time for a national policy? by Lindkær Jensen, N. H., Cook, T. M., Kelly, F. E.

“…Summary The Fourth National Audit Project (NAP4) recommended airway training for trainee and trained anaesthetists. As the skills required for management of…”
Get full text