Search Results - "Jensen, Lars Jørn"

Functional, Structural and Proteomic Effects of Ageing in Resistance Arteries by Jensen, Lars Jørn

“…The normal ageing process affects resistance arteries, leading to various functional and structural changes. Systolic hypertension is a common occurrence in…”
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Calcium Channels, Clustering, and Single-Amino Acid Control of Blood Pressure and Blood Flow by Jensen, Lars Jørn

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Effect of age on the vascular proteome in middle cerebral arteries and mesenteric resistance arteries in mice by Rabaglino, Maria Belen, Wakabayashi, Masaki, Pearson, James Todd, Jensen, Lars Jørn

“…•31 proteins were differentially expressed by age whereas 172 proteins were differentially expressed by vessel type in young vs. middle-aged mice.•Vitamin B6…”
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Transient Receptor Potential Channels in Cardiovascular Function and Disease by Inoue, Ryuji, Jensen, Lars Jørn, Shi, Juan, Morita, Hiromitsu, Nishida, Motohiro, Honda, Akira, Ito, Yushi

“…Sustained elevation in the intracellular Ca concentration via Ca influx, which is activated by a variety of mechanisms, plays a central regulatory role for…”
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The Vascular Conducted Response in Cerebral Blood Flow Regulation by Jensen, Lars Jørn, Holstein-Rathlou, Niels-Henrik

“…Despite recent advances in our understanding of the molecular and cellular mechanisms behind vascular conducted responses (VCRs) in systemic arterioles, we…”
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Vascular calcium signalling and ageing by Harraz, Osama F., Jensen, Lars Jørn

“…Changes in cellular Ca2+ levels have major influences on vascular function and blood pressure regulation. Vascular smooth muscle cells (SMCs) and endothelial…”
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Aging, calcium channel signaling and vascular tone by Harraz, Osama F., Jensen, Lars Jørn

“…•Calcium signaling in vascular smooth muscle is crucial for arterial tone regulation.•L- and T-type voltage-dependent Ca2+ channels play indispensable and…”
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Effect of TRPA1 activator allyl isothiocyanate (AITC) on rat dural and pial arteries by Hansted, Anna Koldbro, Bhatt, Deepak Kumar, Olesen, Jes, Jensen, Lars Jørn, Jansen-Olesen, Inger

“…Transient receptor potential ankyrin 1 (TRPA1) channels may have a role in migraine as some substances known to cause headache activate the channel. In the…”
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Endothelial Natriuretic Peptide Receptor 1 Play Crucial Role for Acute and Chronic Blood Pressure Regulation by Atrial Natriuretic Peptide by Tokudome, Takeshi, Otani, Kentaro, Mao, Yuanjie, Jensen, Lars Jørn, Arai, Yuji, Miyazaki, Takahiro, Sonobe, Takashi, Pearson, James T., Osaki, Tsukasa, Minamino, Naoto, Ishida, Junji, Fukamizu, Akiyoshi, Kawakami, Hayato, Onozuka, Daisuke, Nishimura, Kunihiro, Miyazato, Mikiya, Nishimura, Hirohito

“…ANP (atrial natriuretic peptide), acting through NPR1 (natriuretic peptide receptor 1), provokes hypotension. Such hypotension is thought to be due to ANP…”
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Lack of tone in mouse small mesenteric arteries leads to outward remodeling, which can be prevented by prolonged agonist-induced vasoconstriction by Klein, Anika, Joseph, Philomeena Daphne, Christensen, Vibeke Grøsfjeld, Jensen, Lars Jørn, Jacobsen, Jens Christian Brings

“…Inward remodeling of resistance vessels is an independent risk factor for cardiovascular events. Thus far, the remodeling process remains incompletely…”
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T-type Ca2+ channels and autoregulation of local blood flow by Jensen, Lars Jørn, Nielsen, Morten Schak, Salomonsson, Max, Sørensen, Charlotte Mehlin

“…L-type voltage gated Ca 2+ channels are considered to be the primary source of calcium influx during the myogenic response. However, many vascular beds also…”
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PIP2 modulation of Slick and Slack K+ channels by Tejada, Maria de los Angeles, Jensen, Lars Jørn, Klaerke, Dan A.

“…► Slick (Slo2.1) and Slack (Slo2.2) K+ channels are expressed in CNS and the heart. ► The channels control basal excitability and are involved in cell volume…”
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Is there a role for T-type Ca2+ channels in regulation of vasomotor tone in mesenteric arterioles? by Jensen, Lars Jørn, Holstein-Rathlou, Niels-Henrik

“…The largest peripheral blood pressure drop occurs in terminal arterioles (<40 microm lumen diameter). L-type voltage-dependent Ca2+ channels (VDCCs) are…”
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Oxygen sensing and conducted vasomotor responses in mouse cremaster arterioles in situ by Ngo, Anh Thuc, Jensen, Lars Jørn, Riemann, Mads, Holstein-Rathlou, Niels-Henrik, Torp-Pedersen, Christian

“…This study examines mechanisms by which changes in tissue oxygen tension elicit vasomotor responses and whether localized changes in oxygen tension initiates…”
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The role of L- and T-type calcium channels in local and remote calcium responses in rat mesenteric terminal arterioles by Braunstein, Thomas Hartig, Inoue, Ryuji, Cribbs, Leanne, Oike, Masahiro, Ito, Yushi, Holstein-Rathlou, Niels-Henrik, Jensen, Lars Jørn

“…The roles of intercellular communication and T-type versus L-type voltage-dependent Ca(2+) channels (VDCCs) in conducted vasoconstriction to local KCl-induced…”
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Applicability of Cable Theory to Vascular Conducted Responses by Hald, Bjørn Olav, Jensen, Lars Jørn, Sørensen, Preben Graae, Holstein-Rathlou, Niels-Henrik, Brings Jacobsen, Jens Christian

“…Conduction processes in the vasculature have traditionally been described using cable theory, i.e., locally induced signals decaying passively along the…”
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BKCa and KV channels limit conducted vasomotor responses in rat mesenteric terminal arterioles by Hald, Bjørn Olav, Jacobsen, Jens Christian Brings, Braunstein, Thomas Hartig, Inoue, Ryuji, Ito, Yushi, Sørensen, Preben Graae, Holstein-Rathlou, Niels-Henrik, Jensen, Lars Jørn

“…Intracellular Ca 2+ signals underlying conducted vasoconstriction to local application of a brief depolarizing KCl stimulus was investigated in rat mesenteric…”
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Age‐dependent impact of CaV3.2 T‐type calcium channel deletion on myogenic tone and flow‐mediated vasodilatation in small arteries by Mikkelsen, Miriam F., Björling, Karl, Jensen, Lars Jørn

“…Key points Blood pressure and flow exert mechanical forces on the walls of small arteries, which are detected by the endothelial and smooth muscle cells, and…”
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Endothelial Natriuretic Peptide Receptor 1 Play Crucial Role for Acute and Chronic Blood Pressure Regulation by Atrial Natriuretic Peptide by Tokudome, Takeshi, Otani, Kentaro, Mao, Yuanjie, Jensen, Lars Jørn, Arai, Yuji, Miyazaki, Takahiro, Sonobe, Takashi, Pearson, James T., Osaki, Tsukasa, Minamino, Naoto, Ishida, Junji, Fukamizu, Akiyoshi, Kawakami, Hayato, Onozuka, Daisuke, Nishimura, Kunihiro, Miyazato, Mikiya, Nishimura, Hirohito

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Age-dependent impact of Ca V 3.2 T-type calcium channel deletion on myogenic tone and flow-mediated vasodilatation in small arteries by Mikkelsen, Miriam F, Björling, Karl, Jensen, Lars Jørn

“…Blood pressure and flow exert mechanical forces on the walls of small arteries, which are detected by the endothelial and smooth muscle cells, and lead to…”
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