Search Results - "Jensen, Kirsty"

The role of Mce proteins in Mycobacterium avium paratuberculosis infection by Blake, Rosemary, Jensen, Kirsty, Mabbott, Neil, Hope, Jayne, Stevens, Joanne

“…Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s Disease, a chronic granulomatous enteritis of ruminants. MAP…”
Get full text

Differential response of bovine mammary epithelial cells to Staphylococcus aureus or Escherichia coli agonists of the innate immune system by Gilbert, Florence B, Cunha, Patricia, Jensen, Kirsty, Glass, Elizabeth J, Foucras, Gilles, Robert-Granié, Christèle, Rupp, Rachel, Rainard, Pascal

“…Mastitis caused by Escherichia coli and Staphylococcus aureus is a major pathology of dairy cows. To better understand the differential response of the mammary…”
Get full text

Susceptibility to disease (tropical theileriosis) is associated with differential expression of host genes that possess motifs recognised by a pathogen DNA binding protein by Larcombe, Stephen D, Capewell, Paul, Jensen, Kirsty, Weir, William, Kinnaird, Jane, Glass, Elizabeth J, Shiels, Brian R

“…Knowledge of factors that influence the outcome of infection are crucial for determining the risk of severe disease and requires the characterisation of…”
Get full text

Interleukin 10 knock-down in bovine monocyte-derived macrophages has distinct effects during infection with two divergent strains of Mycobacterium bovis by Jensen, Kirsty, Stevens, Joanne M, Glass, Elizabeth J

“…Mycobacterium bovis is the causative agent of bovine tuberculosis (TB), a cattle disease of global importance. M. bovis infects bovine macrophages (Mø) and…”
Get full text

The Development of 3D Bovine Intestinal Organoid Derived Models to Investigate Mycobacterium Avium ssp Paratuberculosis Pathogenesis by Blake, Rosemary, Jensen, Kirsty, Mabbott, Neil, Hope, Jayne, Stevens, Joanne

“…Mycobacterium avium subspecies paratuberculosis (MAP) is the etiological agent of Johne's Disease, a chronic enteritis of ruminants prevalent across the world…”
Get full text

Differential role of M cells in enteroid infection by Mycobacterium avium subsp. paratuberculosis and Salmonella enterica serovar Typhimurium by Alfituri, Omar A, Blake, Rosemary, Jensen, Kirsty, Mabbott, Neil A, Hope, Jayne, Stevens, Joanne M

“…Infection of ruminants such as cattle with subsp (MAP) causes Johne's disease, a disease characterized by chronic inflammation of the small intestine and…”
Get full text

TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility by Chaussepied, Marie, Janski, Natacha, Baumgartner, Martin, Lizundia, Regina, Jensen, Kirsty, Weir, William, Shiels, Brian R, Weitzman, Jonathan B, Glass, Elizabeth J, Werling, Dirk, Langsley, Gordon

“…Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible…”
Get full text

Resistance and susceptibility to a protozoan parasite of cattle—Gene expression differences in macrophages from different breeds of cattle by Glass, Elizabeth J., Jensen, Kirsty

“…Cattle infected with the tick-borne protozoan, Theileria annulata, usually undergo severe morbidity, and mortality ensues in a high proportion of animals…”
Get full text

Differences in the transcriptional responses induced by Theileria annulata infection in bovine monocytes derived from resistant and susceptible cattle breeds by Jensen, Kirsty, Paxton, Edith, Waddington, David, Talbot, Richard, Darghouth, Mohamed A., Glass, Elizabeth J.

“…Tropical theileriosis is a cattle disease of global economic importance, caused by the tick-borne protozoan parasite Theileria annulata. Conventional control…”
Get full text

Inflammasome Activation in Bovine Peripheral Blood-Derived Macrophages Is Associated with Actin Rearrangement by Tahoun, Amin, Jensen, Kirsty, El-Sharkawy, Hanem, Gally, David, Rizk, Amira M, Ajarem, Jamaan, Allam, Ahmed, Mahmoud, Ayman M

“…Inflammation is critical for infection control and acts as an arsenal defense mechanism against invading microbes through activation of the host immune system…”
Get full text

Strengthening insights into host responses to mastitis infection in ruminants by combining heterogeneous microarray data sources by Genini, S, Badaoui, B, Sclep, G, Bishop, S.C, Waddington, D, Pinard van der Laan, M.H, Klopp, Ch, Cabau, C, Seyfert, H.M, Petzl, W, Jensen, K, Glass, E.J, Greeff, A. de, Smith, H.E, Smits, M.A, Olsaker, I, Boman, G.M, Pisoni, G, Moroni, P, Castiglioni, B, Cremonesi, P, Corvo, M. del, Foulon, E, Foucras, G, Rupp, R, Giuffra, E

“…Gene expression profiling studies of mastitis in ruminants have provided key but fragmented knowledge for the understanding of the disease. A systematic…”
Get full text

Comparative genomics of Toll-like receptor signalling in five species by Jann, Oliver C, King, Annemarie, Corrales, Nestor Lopez, Anderson, Susan I, Jensen, Kirsty, Ait-Ali, Tahar, Tang, Haizhou, Wu, Chunhua, Cockett, Noelle E, Archibald, Alan L, Glass, Elizabeth J

“…Over the last decade, several studies have identified quantitative trait loci (QTL) affecting variation of immune related traits in mammals. Recent studies in…”
Get full text

Development and validation of a bovine macrophage specific cDNA microarray by Jensen, Kirsty, Talbot, Richard, Paxton, Edith, Waddington, David, Glass, Elizabeth J

“…The response of macrophages to danger signals is an important early stage in the immune response. Our understanding of this complex event has been furthered by…”
Get full text

Susceptibility to disease by Larcombe, Stephen D, Capewell, Paul, Jensen, Kirsty, Weir, William, Kinnaird, Jane, Glass, Elizabeth J, Shiels, Brian R

“…Background Knowledge of factors that influence the outcome of infection are crucial for determining the risk of severe disease and requires the…”
Get full text

Living with the enemy or uninvited guests: Functional genomics approaches to investigating host resistance or tolerance traits to a protozoan parasite, Theileria annulata, in cattle by Glass, Elizabeth J., Crutchley, Sarah, Jensen, Kirsty

“…Many breeds of cattle with long histories of living in areas of endemic disease have evolved mechanisms that enable them to co-exist with specific pathogens…”
Get full text

Analysis of the real EADGENE data set : Multivariate approaches and post analysis (Open Access publication) by SØRENSEN, Peter, BONNET, Agnès, HULSEGGE, Ina, JAFFREZIC, Florence, JENSEN, Kirsty, JIANG, Li, DE KONING, Dirk-Jan, LE CAO, Kim-Anh, NIE, Haisheng, PETZL, Wolfram, POOL, Marco H, ROBERT-GRANIE, Christèle, BUITENHUIS, Bart, SAN CRISTOBAL, Magali, LUND, Mogens Sandø, VAN SCHOTHORST, Evert M, SCHUBERTH, Hans-Joachim, SEYFERT, Hans-Martin, TOSSER-KLOPP, Gwenola, WADDINGTON, David, WATSON, Michael, YANG, Wei, ZERBE, Holm, CLOSSET, Rodrigue, DEJEAN, Sébastien, DELMAS, Céline, DUVAL, Mylène, GLASS, Liz, HEDEGAARD, Jakob, HORNSHØJ, Henrik

“…The aim of this paper was to describe, and when possible compare, the multivariate methods used by the participants in the EADGENE WP1.4 workshop. The first…”
Get full text

Escherichia coli- and Staphylococcus aureus-induced mastitis differentially modulate transcriptional responses in neighbouring uninfected bovine mammary gland quarters by Jensen, Kirsty, Günther, Juliane, Talbot, Richard, Petzl, Wolfram, Zerbe, Holm, Schuberth, Hans-Joachim, Seyfert, Hans-Martin, Glass, Elizabeth J

“…The most important disease of dairy cattle is mastitis, caused by the infection of the mammary gland by various micro-organisms. Although the transcriptional…”
Get full text

Variation in the Early Host-Pathogen Interaction of Bovine Macrophages with Divergent Mycobacterium bovis Strains in the United Kingdom by Jensen, Kirsty, Gallagher, Iain J, Johnston, Nicholas, Welsh, Michael, Skuce, Robin, Williams, John L, Glass, Elizabeth J

“…Bovine tuberculosis has been an escalating animal health issue in the United Kingdom since the 1980s, even though control policies have been in place for over…”
Get full text

Quantifying Mycobacterium avium subspecies paratuberculosis infection of bovine monocyte derived macrophages by confocal microscopy by Mathie, Heather A., Jensen, Kirsty, Stevens, Joanne M., Glass, Elizabeth J., Hope, Jayne C.

“…Quantification of Mycobacterium avium subspecies paratuberculosis (MAP) during in vitro infection experiments is challenging due to limitations of currently…”
Get full text

Host species adaptation of TLR5 signalling and flagellin recognition by Tahoun, Amin, Jensen, Kirsty, Corripio-Miyar, Yolanda, McAteer, Sean, Smith, David G. E., McNeilly, Tom N., Gally, David L., Glass, Elizabeth J.

“…Toll-like receptor 5 (TLR5) recognition of flagellin instigates inflammatory signalling. Significant sequence variation in TLR5 exists between animal species…”
Get full text