Search Results - "Jensen, Kamilla E."
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BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity
Published in Nature communications (15-11-2016)“…Oncogene-evoked replication stress (RS) fuels genomic instability in diverse cancer types. Here we report that BRCA1, traditionally regarded a tumour…”
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VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance
Published in Neuro-oncology (Charlottesville, Va.) (09-10-2018)“…Glioblastoma ranks among the most lethal cancers, with current therapies offering only palliation. Paracrine vascular endothelial growth factor (VEGF)…”
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A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma
Published in Journal of medicinal chemistry (11-02-2021)“…Despite the recent advances in cancer therapeutics, highly aggressive cancer forms, such as glioblastoma (GBM), still have very low survival rates. The…”
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Author Correction: BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity
Published in Nature communications (19-12-2018)“…This Article contains an error in the spelling of the author Kjeld Møllgård, which is incorrectly given as Kjeld Møllgaard. The error has not been fixed in the…”
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Development of a highly sensitive chemiluminescence immunoassay for quantification of aggrecanase-generated ARGS aggrecan fragments in serum
Published in Osteoarthritis and cartilage open (01-06-2021)“…Cartilage degradation is a hallmark of osteoarthritis (OA). Aggrecan, a major proteoglycan of articular cartilage extracellular matrix (ECM), is degraded by…”
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Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA
Published in PloS one (25-03-2011)“…In Plasmodium falciparum malaria endemic areas placental malaria (PM) is an important complication of malaria. The recurrence of malaria in primigravidae women…”
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Structural and Functional Insight into How the Plasmodium falciparum VAR2CSA Protein Mediates Binding to Chondroitin Sulfate A in Placental Malaria
Published in The Journal of biological chemistry (06-07-2012)“…Malaria is a major global health problem. Pregnant women are susceptible to infection regardless of previously acquired immunity. Placental malaria is caused…”
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Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy
Published in Neuro-oncology (Charlottesville, Va.) (14-02-2023)“…Glioblastoma (GBM) is a highly lethal malignancy for which neoangiogenesis serves as a defining hallmark. The anti-VEGF antibody, bevacizumab, has been…”
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Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma
Published in Molecular oncology (01-05-2016)“…Recent clinical trials have demonstrated that targeting chromatin remodeling factors is as a promising strategy for the treatment of glioblastoma (GBM). We and…”
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CSIG-05. THE HISTONE CHAPERONE Spt6 IS REQUIRED FOR GENOMIC STABILITY OF GLIOBLASTOMA CANCER STEM-LIKE CELLS
Published in Neuro-oncology (Charlottesville, Va.) (06-11-2017)“…Rampant genomic instability is a hallmark of glioblastoma (GBM). Despite recent advances in our understanding of this deadly disease, molecular mechanism…”
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CBIO-35THE ROLE OF Spt6 IN GLIOBLASTOMA MAINTENANCE AND THERAPEUTIC RESISTANCE
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2015)Get full text
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CBIO-15NON-METABOLIC FUNCTION OF PHOSPHOFRUCTOKINASE-1 IN GLIOBLASTOMA MAINTENANCE
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2015)Get full text
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CB-05THE ROLE OF Emb-5 IN GLIOBLASTOMA MAINTENANCE AND THERAPEUTIC RESISTANCE
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2014)“…Glioblastoma Multiforme (GBM) is among the most lethal of solid cancers in adults. GBM is associated with a median survival of only approximately 15 months…”
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CB-05 THE ROLE OF Emb-5 IN GLIOBLASTOMA MAINTENANCE AND THERAPEUTIC RESISTANCE
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2014)“…Glioblastoma Multiforme (GBM) is among the most lethal of solid cancers in adults. GBM is associated with a median survival of only approximately 15 months…”
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