Search Results - "Jensen, Jordan R"
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Ligand polarizability contributes to tau fibril binding affinity
Published in Bioorganic & medicinal chemistry (01-09-2011)“…Whole brain imaging of tau-bearing neurofibrillary lesions has the potential to improve the premortem diagnosis and staging of Alzheimer’s disease. Diverse…”
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Small-Molecule Mediated Neuroprotection in an In Situ Model of Tauopathy
Published in Neurotoxicity research (01-04-2009)“…Small-molecule inhibitors of neurofibrillary lesion formation may have utility for treatment of Alzheimer’s disease and certain forms of frontotemporal lobar…”
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Research towards tau imaging
Published in Journal of Alzheimer's disease (01-01-2011)“…Tau-bearing neurofibrillary lesions present a promising biomarker for premortem diagnosis and staging of Alzheimer's disease and certain forms of…”
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The relation of religion and spirituality to time management: examining the lives and careers of FranklinCovey co-founders - Hyrum W. Smith & Stephen R. Covey
Published in Journal of management, spirituality & religion (02-10-2017)“…The relation of time, and the management thereof, to any human endeavor is self-evident from the simple standpoint that all cognitive, emotional, spiritual,…”
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Ligand electronic properties modulate tau filament binding site density
Published in Biophysical chemistry (01-08-2012)“…Small molecules that bind tau-bearing neurofibrillary lesions are being sought for premortem diagnosis, staging, and treatment of Alzheimer's disease and other…”
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Potent inhibition of tau fibrillization with a multivalent ligand
Published in Biochemical and biophysical research communications (09-11-2007)“…Small-molecule inhibitors of tau fibrillization are under investigation as tools for interrogating the tau aggregation pathway and as potential therapeutic…”
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Modulation and detection of tau aggregation with small-molecule ligands
Published in Current Alzheimer research (01-10-2009)“…Recent results from high-throughput and other screening approaches reveal that small molecules can directly interact with recombinant full-length tau monomers…”
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Substrate-Induced Changes in the Ammonia Channel for Imidazole Glycerol Phosphate Synthase
Published in Biochemistry (Easton) (17-06-2003)“…IGP synthase is a glutamine amidotransferase that incorporates ammonia derived from glutamine into the unusual nucleotide, N…”
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P2-179: Small-molecule probes of tau fibrillization
Published in Alzheimer's & dementia (01-07-2008)Get full text
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