Search Results - "Jenny, Matthew J."

Characterization of heme oxygenase and biliverdin reductase gene expression in zebrafish (Danio rerio): Basal expression and response to pro-oxidant exposures by Holowiecki, Andrew, O'Shields, Britton, Jenny, Matthew J.

“…While heme is an important cofactor for numerous proteins, it is highly toxic in its unbound form and can perpetuate the formation of reactive oxygen species…”
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Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress by Holowiecki, Andrew, O'Shields, Britton, Jenny, Matthew J.

“…Heme oxygenase 1 (HMOX1) degrades heme into biliverdin, which is subsequently converted to bilirubin by biliverdin reductase (BVRa or BVRb) in a manner…”
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The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin by Hahn, Mark E, McArthur, Andrew G, Karchner, Sibel I, Franks, Diana G, Jenny, Matthew J, Timme-Laragy, Alicia R, Stegeman, John J, Woodin, Bruce R, Cipriano, Michael J, Linney, Elwood

“…Oxidative stress is an important mechanism of chemical toxicity, contributing to teratogenesis and to cardiovascular and neurodegenerative diseases. Developing…”
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Nrf2b, Novel Zebrafish Paralog of Oxidant-responsive Transcription Factor NF-E2-related Factor 2 (NRF2) by Timme-Laragy, Alicia R., Karchner, Sibel I., Franks, Diana G., Jenny, Matthew J., Harbeitner, Rachel C., Goldstone, Jared V., McArthur, Andrew G., Hahn, Mark E.

“…NF-E2-related factor 2 (NRF2; also called NFE2L2) and related NRF family members regulate antioxidant defenses by activating gene expression via antioxidant…”
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Role of AHR2 in the Expression of Novel Cytochrome P450 1 Family Genes, Cell Cycle Genes, and Morphological Defects in Developing Zebra Fish Exposed to 3,3′,4,4′,5-Pentachlorobiphenyl or 2,3,7,8-Tetrachlorodibenzo-p-dioxin by Jönsson, Maria E., Jenny, Matthew J., Woodin, Bruce R., Hahn, Mark E., Stegeman, John J.

“…Halogenated agonists for the aryl hydrocarbon receptor (AHR), such as 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD),…”
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Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator by Evans, Brad R, Karchner, Sibel I, Allan, Lenka L, Pollenz, Richard S, Tanguay, Robert L, Jenny, Matthew J, Sherr, David H, Hahn, Mark E

“…Activation of the aryl hydrocarbon receptor (AHR) by 2,3,7,8-tetrachlorodibenzo-p-dioxin causes altered gene expression and toxicity. The AHR repressor (AHRR)…”
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Transcriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic killifish (Fundulus heteroclitus) from a marine Superfund site by Oleksiak, Marjorie F, Karchner, Sibel I, Jenny, Matthew J, Franks, Diana G, Welch, David B Mark, Hahn, Mark E

“…Populations of Atlantic killifish (Fundulus heteroclitus) have evolved resistance to the embryotoxic effects of polychlorinated biphenyls (PCBs) and other…”
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Distinct Roles of Two Zebrafish AHR Repressors (AHRRa and AHRRb) in Embryonic Development and Regulating the Response to 2,3,7,8-Tetrachlorodibenzo-p-dioxin by Jenny, Matthew J., Karchner, Sibel I., Franks, Diana G., Woodin, Bruce R., Stegeman, John J., Hahn, Mark E.

“…The aryl hydrocarbon receptor (AHR) repressor (AHRR), an AHR-related basic helix-loop-helix/Per-AHR nuclear translocator-Sim protein, is regulated by an…”
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New cytochrome P450 1B1, 1C2 and 1D1 genes in the killifish Fundulus heteroclitus: Basal expression and response of five killifish CYP1s to the AHR agonist PCB126 by Zanette, Juliano, Jenny, Matthew J., Goldstone, Jared V., Woodin, Bruce R., Watka, Lauren A., Bainy, Afonso C.D., Stegeman, John J.

“…Knowledge of the complement of cytochrome P450 (CYP) genes is essential to understanding detoxification and bioactivation mechanisms for organic contaminants…”
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The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish by Jönsson, Maria E., Franks, Diana G., Woodin, Bruce R., Jenny, Matthew J., Garrick, Rita A., Behrendt, Lars, Hahn, Mark E., Stegeman, John J.

“…The tryptophan photooxidation product 6-formylindolo[3,2-b]carbazole (FICZ) has been proposed as a physiological ligand for the mammalian aryl hydrocarbon…”
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The Active Form of Human Aryl Hydrocarbon Receptor (AHR) Repressor Lacks Exon 8, and Its Pro185 and Ala185 Variants Repress both AHR and Hypoxia-Inducible Factor by Karchner, Sibel I., Jenny, Matthew J., Tarrant, Ann M., Evans, Brad R., Kang, Hyo Jin, Bae, Insoo, Sherr, David H., Hahn, Mark E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Corrigendum to ‘Characterization of heme oxygenase and biliverdin reductase gene expression in zebrafish (Danio rerio): Basal expression and response to pro-oxidant exposures’ [Toxicol. Appl. Pharmacol. 311 (2016) 74–87] by Holowiecki, Andrew, O'Shields, Britton, Jenny, Matthew J.

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A rapid return to normal: temporal gene expression patterns following cold exposure in the bumble bee Bombus impatiens by Verble, Kelton M, Keaveny, Ellen C, Rahman, Sarthok Rasique, Jenny, Matthew J, Dillon, Michael E, Lozier, Jeffrey D

“…Bumble bees are common in cooler climates and many species likely experience periodic exposure to very cold temperatures, but little is known about the…”
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Comparative physiological, biochemical and molecular thermal stress response profiles for two unionid freshwater mussel species by Payton, Samantha L, Johnson, Paul D, Jenny, Matthew J

“…Freshwater mussels, aquatic keystone species, are in global decline. Long life spans, sedentary lifestyles, and unique reproductive strategies involving…”
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cDNA Microarray for Crassostrea virginica and C. gigas by Jenny, Matthew J, Chapman, Robert W, Mancia, Annalaura, Chen, Yian A, McKillen, David J, Trent, Hal, Lang, Paul, Escoubas, Jean-Michel, Bachere, Evelyne, Boulo, Viviane, Liu, Z. John, Gross, Paul S, Cunningham, Charles, Cupit, Pauline M, Tanguy, Arnaud, Guo, Ximing, Moraga, Dario, Boutet, Isabelle, Huvet, Arnaud, De Guise, Sylvain, Almeida, Jonas S, Warr, Gregory W

“…The eastern oyster, Crassostrea virginica, and the Pacific oyster, C. gigas, are species of global economic significance as well as important components of…”
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Knockdown of a zebrafish aryl hydrocarbon receptor repressor (AHRRa) affects expression of genes related to photoreceptor development and hematopoiesis by Aluru, Neelakanteswar, Jenny, Matthew J, Hahn, Mark E

“…The aryl hydrocarbon receptor repressor (AHRR) is a transcriptional repressor of aryl hydrocarbon receptor (AHR) and hypoxia-inducible factor (HIF) and is…”
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New Resources for Marine Genomics: Bacterial Artificial Chromosome Libraries for the Eastern and Pacific Oysters (Crassostrea virginica and C. gigas) by Cunningham, Charles, Hikima, Jun-ichi, Jenny, Matthew J, Chapman, Robert W, Fang, Guang-Chen, Saski, Chris, Lundqvist, Mats L, Wing, Rod A, Cupit, Pauline M, Gross, Paul S, Warr, Greg W, Tomkins, Jeff P

“…Large-insert genomic bacterial artificial chromosome (BAC) libraries of two culturally and economically important oyster species, Crassostrea virginica and C…”
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Phylogenetic Analysis of Molluscan Metallothioneins: Evolutionary Insight from Crassostrea virginica by Jenny, Matthew J., Payton, Samantha L., Baltzegar, David A., Lozier, Jeffrey D.

“…Mechanisms by which organisms genetically adapt to environmental conditions are of fundamental importance to studies of evolutionary biology and environmental…”
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Marine genomics: a clearing-house for genomic and transcriptomic data of marine organisms by McKillen, David J, Chen, Yian A, Chen, Chuming, Jenny, Matthew J, Trent, 3rd, Harold F, Robalino, Javier, McLean, Jr, David C, Gross, Paul S, Chapman, Robert W, Warr, Gregory W, Almeida, Jonas S

“…The Marine Genomics project is a functional genomics initiative developed to provide a pipeline for the curation of Expressed Sequence Tags (ESTs) and gene…”
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Identification and expression of multiple CYP1-like and CYP3-like genes in the bivalve mollusk Mytilus edulis by Zanette, Juliano, Jenny, Matthew J., Goldstone, Jared V., Parente, Thiago, Woodin, Bruce R., Bainy, Afonso C.D., Stegeman, John J.

“…► Five new CYP genes were characterized in the blue mussel, Mytilus edulis. ► Transcript levels of these CYPs were highest in digestive gland and labial palps…”
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