Search Results - "Jenniskens, Guido J."
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Control of organization and function of muscle and tendon by thrombospondin-4
Published in Matrix biology (01-07-2014)“…Thrombospondins (TSPs) are multifunctional proteins that are deposited in the extracellular matrix where they directly affect the function of vascular and…”
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Characterization of Anti-heparan Sulfate Phage Display Antibodies AO4B08 and HS4E4
Published in The Journal of biological chemistry (20-07-2007)“…Heparan sulfates (HS) are linear carbohydrate chains, covalently attached to proteins, that occur on essentially all cell surfaces and in extracellular…”
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Large, Tissue-regulated Domain Diversity of Heparan Sulfates Demonstrated by Phage Display Antibodies
Published in The Journal of biological chemistry (29-03-2002)“…Heparan sulfates (HS) are long, linear polysaccharides with a high degree of variability. They bind to a vast number of proteins such as growth factors and…”
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Heparan Sulfate Heterogeneity in Skeletal Muscle Basal Lamina: Demonstration by Phage Display-Derived Antibodies
Published in The Journal of neuroscience (01-06-2000)“…The basal lamina (BL) enveloping skeletal muscle fibers contains different glycoproteins, including proteoglycans. To obtain more information on the…”
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Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88
Published in Glycobiology (Oxford) (01-02-2010)“…Heparan sulfates (HS) bind a diversity of protein ligands on the cell surface and in the extracellular matrix and thus can modulate cell signaling. The state…”
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Loss of heparan sulfate glycosaminoglycan assembly in podocytes does not lead to proteinuria
Published in Kidney international (01-08-2008)“…Podocytes synthesize the majority of the glomerular basement membrane components with some contribution from the glomerular capillary endothelial cells. The…”
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Spatiotemporal distribution of heparan sulfate epitopes during myogenesis and synaptogenesis: A study in developing mouse intercostal muscle
Published in Developmental dynamics (01-09-2002)“…Formation of a basal lamina (BL) ensheathing developing skeletal muscle cells is one of the earliest events in mammalian skeletal muscle myogenesis…”
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Disturbed Ca2+ kinetics in N-deacetylase/N-sulfotransferase-1 defective myotubes
Published in Journal of cell science (01-06-2003)“…The biosynthesis of heparan sulfate, present on the cell surface and in the basal lamina surrounding cells, is a multistep process in which each step is…”
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Heparan sulfates in skeletal muscle development and physiology
Published in Journal of cellular physiology (01-02-2006)“…Recent years have seen an emerging interest in the composition of the skeletal muscle extracellular matrix (ECM) and in the developmental and physiological…”
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Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation
Published in International journal of oncology (01-04-2008)“…The growth-promoting polyamines are polybasic compounds that efficiently enter cancer cells by as yet incompletely defined mechanisms. Strategies to inhibit…”
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Phage display-derived human antibodies against specific glycosaminoglycan epitopes
Published in Methods in enzymology (2006)“…Glycosaminoglycans (GAGs) are long unbranched polysaccharides, most of which are linked to a core protein to form proteoglycans. Depending on the nature of…”
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Phenotypic knock out of heparan sulfates in myotubes impairs excitation-induced calcium spiking
Published in The FASEB journal (01-05-2003)“…Little is known about the physiological functions of heparan sulfates (HSs), which are present in the basal lamina surrounding skeletal muscle fibers. Here, we…”
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Loss of heparan sulfate glycosaminoglycan assembly in podocytes does not lead to proteinuria. Commentary
Published in Kidney international (2008)Get full text
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14
Phenotypic knockout of heparan sulfates in myotubes impairs excitation‐induced calcium spiking
Published in The FASEB journal (01-05-2003)“…ABSTRACT Little is known about the physiological functions of heparan sulfates (HSs), which are present in the basal lamina surrounding skeletal muscle fibers…”
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