Search Results - "Jennings, F. W."

Astrocyte activation correlates with cytokine production in central nervous system of Trypanosoma brucei brucei-infected mice by Hunter, C A, Jennings, F W, Kennedy, P G, Murray, M

“…During the late-stage disease associated with human African trypanosomiasis, caused by infection with either Trypanosoma gambiense or T. rhodesiense, parasites…”
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Combination chemotherapy of CNS trypanosomiasis by Jennings, F W

“…The progress which has been made in the treatment of experimental CNS trypanosomiasis with combination chemotherapy is reviewed. The most significant has been…”
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Immunopathology of experimental African sleeping sickness: detection of cytokine mRNA in the brains of Trypanosoma brucei brucei-infected mice by HUNTER, C. A, GOW, J. W, KENNEDY, P. G. E, JENNINGS, F. W, MURRAY, M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Topical chemotherapy for experimental African trypanosomiasis with cerebral involvement: the use of melarsoprol combined with the 5‐nitroimidazole, megazol by Jennings, F. W., Chauvière, G., Viode, C., Murray, M.

“…Summary Megazol, one of a number of related 5‐nitroimidazoles, can be dissolved in dimethylsulphoxide and the solution can be converted into a gel by the…”
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Suramin treatment of experimental Trypanosoma brucei infection of the central nervous system by Jennings, F W

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Topical chemotherapy for experimental murine African CNS‐trypanosomiasis: the successful use of the arsenical, melarsoprol, combined with the 5‐nitroimidazoles, fexinidazole or MK‐436 by Jennings, F. W., Atouguia, J. M., Murray, M.

“…Summary The 5‐nitroimidazoles, MK‐436 and fexinidazole dissolved in dimethylsulphoxide can be converted by the addition of hydroxypropylcellulose into gels…”
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Successful treatment of experimental murine Trypanosoma brucei infection with topical melarsoprol gel by Atouguia, J M, Jennings, F W, Murray, M

“…Melarsoprol gel applied topically (0.1 mL for at least 2 d) can cure late-stage Trypanosoma brucei brucei and T. b. rhodesiense infections in mice. The best…”
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Secondary bacterial infection in plasma endotoxin levels and the acute-phase response of mice infected with Trypanosoma brucei brucei by NGURE, R, BURKE, J, ECKERSALL, P.D, JENNINGS, F.W, MBAI, F.N, MURRAY, M

“…Murine Trypanosoma brucei brucei infection leads to elevated plasma endotoxin-like activity levels not related to parasitaemia levels accompanied by the…”
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Acute phase response in mice experimentally infected with Trypanosoma congolense: A molecular gauge of parasite–host interaction by Ngure, R.M., Eckersall, P.D., Jennings, F.W., Mburu, J., Burke, J., Mungatana, N., Murray, M.

“…Mice infected with Trypanosoma congolense developed a severe anaemia 1 week after infection, which persisted till treatment with diminazine aceturate when the…”
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Elevation of the concentration of acute phase proteins in dogs infected with Trypanosoma brucei by Ndung'u, J M, Eckersall, P D, Jennings, F W

“…Plasma concentrations of the acute phase proteins (APP), C-reactive protein (CRP) and haptoglobin (Hp), increased markedly following experimental infection of…”
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The rapid development of drug-resistance by Trypanosoma evansi in immunosuppressed mice by Osman, A S, Jennings, F W, Holmes, P H

“…The effect of immunosuppression on the development of drug resistance by trypanosomes was investigated in mice infected with Trypanosoma evansi. As a result of…”
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Lipopolysaccharide binding protein in the acute phase response of experimental murine Trypanosoma brucei brucei infection by Ngure, R.M., Eckersall, P.D., Mungatana, N.K., Mburu, J.N., Jennings, F.W., Burke, J., Murray, M.

“…Cellular responses to lipopolysaccharide (LPS) are enhanced by LPS-binding protein (LBP). The present study investigated the acute phase response of LBP during…”
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Future prospects for the chemotherapy of human trypanosomiasis. 2. Combination chemotherapy and African trypanosomiasis by Jennings, F W

“…This paper reviews the progress which has been achieved with combination chemotherapy of experimental murine central nervous system trypanosomiasis. Successful…”
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Chemotherapy of trypanosomiasis: the potentiation of melarsoprol by concurrent difluoromethylornithine (DFMO) treatment by Jennings, F W

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The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis by Jennings, F. W., Gichuki, C. W., Kennedy, P. G. E., Rodgers, J., Hunter, C. A., Murray, M., Burke, J. M.

“…The treatment of late‐stage human African trypanosomiasis is complicated by a post‐treatment reactive encephalopathy, also referred to as a ‘reactive arsenical…”
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The effect of spiroarsoranes on Trypanosoma brucei brucei and T. b. rhodesiense by LOISEAU, P. M, JENNINGS, F. W, LUBERT, P, WOLF, J. G

“…Topical application and intraperitoneal administration of spiroarsoranes were carried out to cure central nervous system (CNS) trypanosomiasis in the chronic…”
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The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis by Hunter, C A, Jennings, F W, Kennedy, P G, Murray, M

“…The treatment of human African sleeping sickness is complicated by a post-treatment meningoencephalitis that may be fatal. Using a mouse model this study…”
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The importance of 2,3-dimercaptopropinol (British anti-lewisite, BAL) in the trypanocidal activity of topical melarsoprol by Jennings, F.W., Atouguia, J.M., Murray, M.

“…Both melarsomine dichlorhydrate (mel Cy, Cymelarsan®) and melarsen oxide can be dissolved in dimethylsulfoxide and converted into a gel by the addition of…”
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The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis by JENNINGS, F. W, GICHUKI, C. W, KENNEDY, P. G. E, RODGERS, J, HUNTER, C. A, MURRAY, M, BURKE, J. M

“…The treatment of late-stage human African trypanosomiasis is complicated by a post-treatment reactive encephalopathy, also referred to as a 'reactive arsenical…”
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Chemotherapy of Trypanosoma brucei infection of the central nervous system: the use of a rapid chemotherapeutic regimen and the development of post-treatment encephalopathies by Jennings, F W, Hunter, C A, Kennedy, P G, Murray, M

“…The use of a rapid curative chemotherapeutic regimen for experimental infection of the central nervous system (CNS) of mice by Trypanosoma brucei has indicated…”
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