Search Results - "Jennings, C Darrell"
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Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease
Published in Frontiers in immunology (18-10-2019)“…Allogeneic hematopoietic stem cell transplant (allo-HSCT) is often used to treat acute leukemia or defects of hematopoiesis. Its widespread use is hampered by…”
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Alloantibody to a Bw4 Epitope in a Bw4+ B27: 05 Patient
Published in Transplantation (27-10-2014)“…BACKGROUNDAlloantibodies to the Bw4 epitope are known to be heterogeneous, but it is widely assumed that anti-Bw4 alloantibodies arise only in individuals who…”
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c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells
Published in Blood (15-08-2005)“…Several primary murine and human B lymphomas and cell lines were found to constitutively express high levels of the activated form of c-jun N-terminal kinase…”
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Cancer resistance in transgenic mice expressing the SAC module of par-4
Published in Cancer research (Chicago, Ill.) (01-10-2007)“…Prostate apoptosis response-4 (Par-4) is a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal/immortalized cells. The…”
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Multifactorial patterns of gene expression in colonic epithelial cells predict disease phenotypes in experimental colitis
Published in Inflammatory bowel diseases (01-11-2012)“…Background: The pathogenesis of inflammatory bowel disease (IBD) is complex and the need to identify molecular biomarkers is critical. Epithelial cells play a…”
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Anti-IL-23p19 therapy inhibits the adoptive transfer of syngeneic graft-versus-host disease
Published in Cytokine (Philadelphia, Pa.) (01-03-2013)“…► We analyzed the effect of anti-IL-23p19 therapy on development of SGVHD. ► Anti-IL-23p19 therapy altered the induction and adoptive transfer of SGVHD. ►…”
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Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth
Published in Molecular cancer (31-12-2009)“…Previously we have shown that B cell receptor (BCR) expression and B cell receptor signaling pathways are important for the basal growth of B lymphoma cells…”
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Accumulation of CD4+ T cells in the colon of CsA-treated mice following myeloablative conditioning and bone marrow transplantation
Published in American journal of physiology: Gastrointestinal and liver physiology (01-05-2011)“…Syngeneic graft vs. host disease (SGVHD) was first described as a graft vs. host disease-like syndrome that developed in rats following syngeneic bone marrow…”
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Prevalence of SARS-CoV-2 IgG antibodies in health care workers at a tertiary care academic medical center – An assessment of occupational infection risk
Published in American journal of infection control (01-09-2021)“…BACKGROUNDThe purpose of this study was to assess the occupational SARS-CoV-2 infection risk among health care workers (HCW) at University of Kentucky…”
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Association between chronic liver and colon inflammation during the development of murine syngeneic graft-versus-host disease
Published in American journal of physiology: Gastrointestinal and liver physiology (01-09-2010)“…The murine model of cyclosporine A (CsA)-induced syngeneic graft-versus-host disease (SGVHD) is a bone marrow (BM) transplantation model that develops chronic…”
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Cutting Edge: Constitutive B Cell Receptor Signaling Is Critical for Basal Growth of B Lymphoma
Published in The Journal of immunology (1950) (15-05-2006)“…B lymphomas account for the majority of the lymphoma cases. BCR expression appears to be important for B lymphoma because most oncogenes are translocated to…”
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Adoptive transfer of murine syngeneic graft-vs.-host disease by CD4+ T cells
Published in Journal of leukocyte biology (01-12-2007)“…Syngeneic graft‐vs.‐host disease (SGVHD) develops in rodents following the treatment of lethally irradiated, bone marrow (BM) reconstituted animals with a…”
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13
A gut feeling about murine syngeneic GVHD
Published in Chimerism (01-04-2011)“…Murine syngeneic graft-versus-host disease (SGVHD) results in chronic colon and liver inflammation following syngeneic bone marrow transplantation (BMT) and…”
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Spleen tyrosine kinase (Syk), a novel target of curcumin, is required for B lymphoma growth
Published in Journal of Immunology (01-01-2007)“…Curcumin (diferuloylmethane), a component of dietary spice turmeric (Curcuma longa), has been shown in recent studies to have therapeutic potential in the…”
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Idiopathic Pneumonia Syndrome after Allogeneic Bone Marrow Transplantation in Mice . Role of Pretransplant Radiation Conditioning
Published in American journal of respiratory cell and molecular biology (01-06-1999)“…Idiopathic pneumonia syndrome (IPS) is a significant clinical problem encountered among patients treated with bone marrow transplantation (BMT). IPS is…”
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Idiopathic Pneumonia Syndrome in Mice after Allogeneic Bone Marrow Transplantation
Published in American journal of respiratory cell and molecular biology (01-02-1998)“…Pulmonary complications are a major clinical problem following allogeneic bone marrow transplantation (BMT), contributing to more than 30% of…”
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Broadly reactive anti-HLA antibodies after a single unit transfusion with nonleukoreduced red blood cells
Published in The American surgeon (01-03-2014)Get more information
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Commentary: Health care reform and primary care: training physicians for tomorrow's challenges
Published in Academic medicine (01-02-2011)“…Although Congress recently passed health insurance reform legislation, the real catalyst for change in the health care delivery system, the author's argue,…”
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Bleomycin-induced pulmonary fibrosis is independent of eosinophils
Published in Journal of leukocyte biology (01-10-2000)“…Eosinophils have been shown to increase in tissues during many fibrotic conditions and consequently have been suggested to contribute to the development of…”
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Recent advances in flow cytometry : Application to the diagnosis of hematologic malignancy
Published in Blood (15-10-1997)Get full text
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