Search Results - "Jennifer H. -C. Shen"

Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells by Chen, Jun-Jie, Shen, H-C Jennifer, Rivera Rosado, Leslie A, Zhang, Yaqin, Di, Xu, Zhang, Baolin

“…Multiple clinical trials are ongoing to evaluate the potential antitumor activity of human TNF variants, Fas ligand (FasL), TNF-related apoptosis inducing…”
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Multiple Endocrine Neoplasia Type 1 Deletion in Pancreatic α-Cells Leads to Development of Insulinomas in Mice by Shen, H.-C. Jennifer, Ylaya, Kris, Pechhold, Klaus, Wilson, Arianne, Adem, Asha, Hewitt, Stephen M, Libutti, Steven K

“…The pancreatic α- and β-cells are critical components in regulating blood glucose homeostasis via secretion of glucagon and insulin, respectively. Both cell…”
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Wnt4 Overexpression Disrupts Normal Testicular Vasculature and Inhibits Testosterone Synthesis by Repressing Steroidogenic Factor 1/β-Catenin Synergy by Jordan, Brian K., Jennifer H. -C. Shen, Olaso, Robert, Ingraham, Holly A., Vilain, Eric

“…Genetic studies in mice suggest that Wnt4 signaling antagonizes expression of male hormones and effectively blocks male development in the female embryo. We…”
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Recapitulation of Pancreatic Neuroendocrine Tumors in Human Multiple Endocrine Neoplasia Type I Syndrome via Pdx1-Directed Inactivation of Men1 by SHEN, H.-C. Jennifer, MEI HE, SPIEGEL, Allen M, LIBUTTI, Steven K, POWELL, Anathea, ADEM, Asha, LORANG, Dominique, HELLER, Charles, GROVER, Amelia C, YLAYA, Kris, HEWITT, Stephen M, MARX, Stephen J

“…Multiple endocrine neoplasia type 1 (MEN1) is an autosomal syndrome caused by mutations in the MEN1 tumor suppressor gene. Whereas the protein product of MEN1,…”
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Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations by Shen, H-C Jennifer, Adem, Asha, Ylaya, Kris, Wilson, Arianne, He, Mei, Lorang, Dominique, Hewitt, Stephen M, Pechhold, Klaus, Harlan, David M, Lubensky, Irina A, Schmidt, Laura S, Linehan, W Marston, Libutti, Steven K

“…The von Hippel-Lindau (VHL) syndrome is a pleomorphic familial disease characterized by the development of highly vascularized tumors, such as…”
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Expression Signature Developed from a Complex Series of Mouse Models Accurately Predicts Human Breast Cancer Survival by MEI HE, MANGIAMELI, David P, KACHALA, Stefan, HUNTER, Kent, GILLESPIE, John, XIAOPENG BIAN, SHEN, H.-C. Jennifer, LIBUTTI, Steven K

“…Purpose: The capability of microarray platform to interrogate thousands of genes has led to the development of molecular diagnostic tools for cancer patients…”
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Regulation of the Orphan Nuclear Receptor Steroidogenic Factor 1 by Sox Proteins by Shen, Jennifer H.-C, Ingraham, Holly A

“…Steroidogenic factor 1 (SF-1) is an essential factor in endocrine proliferation and gene expression. Despite the fact that SF-1 expression is restricted to…”
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Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development by Egeblad, Mikala, Shen, H.‐C. Jennifer, Behonick, Danielle J., Wilmes, Lisa, Eichten, Alexandra, Korets, Lidiya V., Kheradmand, Farrah, Werb, Zena, Coussens, Lisa M.

“…Recessive inactivating mutations in human matrix metalloproteinase 2 (MMP2, gelatinase A) are associated with syndromes that include abnormal facial…”
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Parathyroid tumor development involves deregulation of homeobox genes by Shen, H-C Jennifer, Rosen, Jennifer E, Yang, Lauren M, Savage, Sharon A, Burns, A Lee, Mateo, Carmen M, Agarwal, Sunita K, Chandrasekharappa, Settara C, Spiegel, Allen M, Collins, Francis S, Marx, Stephen J, Libutti, Steven K

“…Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome caused by mutations in the MEN1 tumor suppressor gene. Loss of the functional…”
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Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development by Egeblad, Mikala, Shen, H.‐C. Jennifer, Behonick, Danielle J., Wilmes, Lisa, Eichten, Alexandra, Korets, Lidiya V., Kheradmand, Farrah, Werb, Zena, Coussens, Lisa M.

“…Top‐view of skull from a newborn Mmp2+/−; Colr/+ mouse stained with alcian blue (for cartilage) and alizarin red (for bone). See Egeblad et al., Developmental…”
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Three-dimensional visualization of blood and lymphatic vasculature in tissue whole mounts using confocal microscopy by Eichten, Alexandra, Shen, H-C Jennifer, Coussens, Lisa M

“…Two vascular systems, cardiovascular and lymphatic, maintain appropriate interstitial and intravascular fluid volume in the body. Each is endowed with innate…”
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Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins by Shen, Jennifer H-C, Ingraham, Holly A

“…Steroidogenic factor 1 (SF-1) is an essential factor in endocrine proliferation and gene expression. Despite the fact that SF-1 expression is restricted to…”
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Deciphering von Hippel-Lindau by Shen, H.-C. Jennifer, Adem, Asha, Ylaya, Kris, Wilson, Arianne, He, Mei, Lorang, Dominique, Hewitt, Stephen M, Pechhold, Klaus, Harlan, David M, Lubensky, Irina A, Schmidt, Laura S, Linehan, W. Marston, Libutti, Steven K

“…The von Hippel-Lindau (VHL) syndrome is a pleomorphic familial disease characterized by the development of highly vascularized tumors, such as…”
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