Search Results - "Jennifer Barks"
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Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis
Published in Journal of inflammation (London, England) (11-08-2010)“…The Janus kinase (JAK) family of tyrosine kinases includes JAK1, JAK2, JAK3 and TYK2, and is required for signaling through Type I and Type II cytokine…”
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Optimizing Small Molecule Inhibitors of Calcium-Dependent Protein Kinase 1 to Prevent Infection by Toxoplasma gondii
Published in Journal of medicinal chemistry (11-04-2013)“…Toxoplasma gondii is sensitive to bulky pyrazolo [3,4-d] pyrimidine (PP) inhibitors due to the presence of a Gly gatekeeper in the essential calcium dependent…”
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Murine Trophoblast Cells Induce NK Cell Interferon-Gamma Production Through KLRK1
Published in Biology of reproduction (01-09-2010)“…Murine models suggest that natural killer (NK) cells are important for normal implantation site development, in part, through the production of interferon…”
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Murine Trophoblast Cells Induce NK Cell Interferon-Gamma Production Through KLRK11
Published in Biology of reproduction (01-09-2010)“…Murine models suggest that natural killer (NK) cells are important for normal implantation site development, in part, through the production of interferon…”
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Discovery of Selective Toxoplasma gondii Dihydrofolate Reductase Inhibitors for the Treatment of Toxoplasmosis
Published in Journal of medicinal chemistry (14-02-2019)“…A safer treatment for toxoplasmosis would be achieved by improving the selectivity and potency of dihydrofolate reductase (DHFR) inhibitors, such as…”
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Optimizing Pyrazolopyrimidine Inhibitors of Calcium Dependent Protein Kinase 1 for Treatment of Acute and Chronic Toxoplasmosis
Published in Journal of medicinal chemistry (11-06-2020)“…Calcium dependent protein kinase 1 (CDPK1) is an essential Ser/Thr kinase that controls invasion and egress by the protozoan parasite . The Gly gatekeeper of…”
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Inhibition of Calcium Dependent Protein Kinase 1 (CDPK1) by Pyrazolopyrimidine Analogs Decreases Establishment and Reoccurrence of Central Nervous System Disease by Toxoplasma gondii
Published in Journal of medicinal chemistry (28-12-2017)“…Calcium dependent protein kinase 1 (CDPK1) is an essential enzyme in the opportunistic pathogen Toxoplasma gondii. CDPK1 controls multiple processes that are…”
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Monoclonal Antibodies to Intracellular Stages of Cryptosporidium parvum Define Life Cycle Progression In Vitro
Published in mSphere (27-06-2018)“…Among the obstacles hindering research is the lack of an culture system that supports complete life development and propagation. This major barrier has led to…”
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Monoclonal Antibodies to Intracellular Stages of Cryptosporidium parvum Define Life Cycle Progression italic toggle="yes">In Vitro /italic
Published in mSphere (01-06-2018)“…ABSTRACT Among the obstacles hindering Cryptosporidium research is the lack of an in vitro culture system that supports complete life development and…”
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TNF-alpha and IL-4 synergistically increase vascular cell adhesion molecule-1 expression in cultured vascular smooth muscle cells
Published in The Journal of immunology (1950) (01-11-1997)“…Vascular cell adhesion molecule-1 (VCAM-1) is expressed on the endothelium and vascular smooth muscle in atherosclerosis, where it is thought to recruit alpha4…”
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Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells
Published in The Journal of clinical investigation (01-01-1995)Get full text
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