Search Results - "Jennie P. Mather"
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Isolation of cancer stem like cells from human adenosquamous carcinoma of the lung supports a monoclonal origin from a multipotential tissue stem cell
Published in PloS one (04-12-2013)“…There is increasing evidence that many solid tumors are hierarchically organized with the bulk tumor cells having limited replication potential, but are…”
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Establishment of human ovarian serous carcinomas cell lines in serum free media
Published in Methods (San Diego, Calif.) (01-03-2012)“…Ovarian cancers are the fifth leading cause of cancer death among US woman. The majority of ovarian cancers belong to a category of serous adenocarcinomas…”
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The glycotope-specific RAV12 monoclonal antibody induces oncosis in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo
Published in Molecular cancer therapeutics (01-03-2007)“…RAV12 is a chimeric antibody that recognizes an N-linked carbohydrate antigen (RAAG12) strongly expressed on multiple solid organ cancers. More than 90% of…”
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Development of an Fc-Enhanced Anti―B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Published in Clinical cancer research (15-07-2012)“…The goal of this research was to harness a monoclonal antibody (mAb) discovery platform to identify cell-surface antigens highly expressed on cancer and…”
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Stem Cell Culture
Published 2008“…The purpose of this volume is to provide a comprehensive resource for researchers in the fields of embyonic, fetal and adult stem cell biology to find methods…”
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Antibody-based identification of cell surface antigens: targets for cancer therapy
Published in Current opinion in pharmacology (01-10-2008)“…The identification of novel cell surface antigens present on tumor cells is crucial for developing new cancer therapies. Intact, viable cancer cells, which…”
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Engineered antibody therapeutics
Published in Advanced drug delivery reviews (07-08-2006)Get full text
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The RAV12 monoclonal antibody recognizes the N-linked glycotope RAAG12: expression in human normal and tumor tissues
Published in Archives of pathology & laboratory medicine (1976) (01-09-2009)“…RAAG12 is a primate-restricted N-linked carbohydrate antigen present on multiple membrane-associated proteins. RAAG12 is recognized by the RAV12 monoclonal…”
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Biological Response to ErbB Ligands in Nontransformed Cell Lines Correlates with a Specific Pattern of Receptor Expression
Published in Endocrinology (Philadelphia) (01-12-1998)“…The human epidermal growth factor receptor (HER or ErbB) family consists of four distinct members, including the epidermal growth factor (EGF) receptor (EGFR,…”
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Secretion of Activin by Interstitial Cells in the Testis
Published in Science (American Association for the Advancement of Science) (20-01-1989)“…Activin, a dimer formed by the $\beta $ subunits of inhibin, has an effect that is opposite to that of inhibin in a number of biological systems. Which cell…”
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Inhibin, activin and the female reproductive axis
Published in Annual review of physiology (01-01-1995)Get full text
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Lindane, an Inhibitor of Gap Junction Formation, Abolishes Oocyte Directed Follicle Organizing Activity in Vitro
Published in Endocrinology (Philadelphia) (01-10-1997)“…Folliculogenesis in the ovary begins before birth with the formation of primordial follicles consisting of an oocyte in the resting meiotic prophase surrounded…”
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Culture of Pluripotent Neural Epithelial Progenitor Cells from E9 Rat Embryo
Published in Methods in Cell Biology (2008)“…The mammalian central nervous system is developmentally derived from neuroepithelial cells in the neural plate. These neuroepithelial cells grow and…”
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Activin stimulates spermatogonial proliferation in germ-Sertoli cell cocultures from immature rat testis
Published in Endocrinology (Philadelphia) (01-12-1990)“…Activin and inhibin are peptide hormones produced in the gonads which may act as autocrine and/or paracrine regulators of testicular function. Sertoli cells…”
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Differentiation of Granulosa Cell Line: Follicle-Stimulating Hormone Induces Formation of Lamellipodia and Filopodia via the Adenylyl Cyclase/Cyclic Adenosine Monophosphate Signal
Published in Endocrinology (Philadelphia) (01-09-2000)“…Abstract FSH plays a crucial role in granulosa cell differentiation and follicular development during the ovulation cycle. The early events of granulosa cell…”
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Inhibin and activin locally regulate rat ovarian folliculogenesis
Published in Endocrinology (Philadelphia) (01-12-1990)“…The role of inhibin and activin in the initiation of follicular development, growth, and atresia was examined. Human recombinant inhibin (1 microgram) was…”
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Effects of temperature shift on cell cycle, apoptosis and nucleotide pools in CHO cell batch cultues
Published in Cytotechnology (Dordrecht) (1997)“…Temperature reduction in CHO cell batch culture may be beneficial in the production of recombinant protein and in maintenance of viability. The effects on cell…”
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Stimulating Effect of Both Human Recombinant Inhibin A and Activin A on Immature Porcine Leydig Cell Functions in Vitro
Published in Endocrinology (Philadelphia) (01-11-1997)“…Abstract In addition to the regulation of FSH secretion, it has been clearly shown that inhibin and activin have paracrine/autocrine effects in the gonads. We…”
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Localization of inhibin and activin binding sites in the testis during development by in situ ligand binding
Published in Biology of reproduction (01-04-1994)“…Inhibin and activin are related proteins thought to be potential paracrine regulators of testicular development and maintenance of spermatogenesis. Messenger…”
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