Search Results - "Jenner, Andrew M."

Long-term cannabidiol treatment prevents the development of social recognition memory deficits in Alzheimer's disease transgenic mice by Cheng, David, Spiro, Adena S, Jenner, Andrew M, Garner, Brett, Karl, Tim

“…Impairments in cognitive ability and widespread pathophysiological changes caused by neurotoxicity, neuroinflammation, oxidative damage, and altered…”
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Lipid pathway alterations in Parkinson's disease primary visual cortex by Cheng, Danni, Jenner, Andrew M, Shui, Guanghou, Cheong, Wei Fun, Mitchell, Todd W, Nealon, Jessica R, Kim, Woojin S, McCann, Heather, Wenk, Markus R, Halliday, Glenda M, Garner, Brett

“…We present a lipidomics analysis of human Parkinson's disease tissues. We have focused on the primary visual cortex, a region that is devoid of pathological…”
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Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue by Kreilaus, Fabian, Spiro, Adena S., McLean, Catriona A., Garner, Brett, Jenner, Andrew M.

“…Aims Cholesterol plays an essential role in membrane structure and function, being especially important in the brain. Alteration of brain cholesterol synthesis…”
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Cholesteryl ester levels are elevated in the caudate and putamen of Huntington’s disease patients by Phillips, Gabrielle R., Hancock, Sarah E., Brown, Simon H. J., Jenner, Andrew M., Kreilaus, Fabian, Newell, Kelly A., Mitchell, Todd W.

“…Huntington’s disease (HD) is an autosomal dominant neurodegenerative illness caused by a mutation in the huntingtin gene (HTT) and subsequent protein (mhtt),…”
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Human fecal water content of phenolics: The extent of colonic exposure to aromatic compounds by Jenner, Andrew M., Rafter, Joseph, Halliwell, Barry

“…Phenolic compounds are not completely absorbed in the small intestine and so enter the colon, where they might exert physiological effects. To identify…”
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An Improved High-Throughput Lipid Extraction Method for the Analysis of Human Brain Lipids by Abbott, Sarah K., Jenner, Andrew M., Mitchell, Todd W., Brown, Simon H. J., Halliday, Glenda M., Garner, Brett

“…We have developed a protocol suitable for high-throughput lipidomic analysis of human brain samples. The traditional Folch extraction (using chloroform and…”
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Phospholipid Profiles Are Selectively Altered in the Putamen and White Frontal Cortex of Huntington's Disease by Phillips, Gabrielle R, Hancock, Sarah E, Jenner, Andrew M, McLean, Catriona, Newell, Kelly A, Mitchell, Todd W

“…Huntington's disease (HD) is a genetic, neurodegenerative illness that onsets in late adulthood as a series of progressive and terminal cognitive, motor, and…”
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The long and the short of Huntington’s disease: how the sphingolipid profile is shifted in the caudate of advanced clinical cases by Phillips, Gabrielle R., Saville, Jennifer T., Hancock, Sarah E., Brown, Simon H. J., Jenner, Andrew M., McLean, Catriona, Fuller, Maria, Newell, Kelly A., Mitchell, Todd W.

“…Abstract Huntington’s disease is a devastating neurodegenerative disorder that onsets in late adulthood as progressive and terminal cognitive, psychiatric and…”
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Changes in cholesterol biosynthetic and transport pathways after excitotoxicity by Kim, Ji-Hyun, Jittiwat, Jinatta, Ong, Wei-Yi, Farooqui, Akhlaq A, Jenner, Andrew M

“…The present study was carried out to elucidate changes in the gene expression and activity of cholesterol biosynthetic enzymes and transporters in the rat…”
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Lipid anti-lipid antibody responses correlate with disease activity in systemic lupus erythematosus by Jovanović, Vojislav, Abdul Aziz, Nurhuda, Lim, Yan Ting, Ng Ai Poh, Amanda, Jin Hui Chan, Sherlynn, Ho Xin Pei, Eliza, Lew, Fei Chuin, Shui, Guanghou, Jenner, Andrew M, Bowen, Li, McKinney, Eoin F, Lyons, Paul A, Kemeny, Michael D, Smith, Kenneth G C, Wenk, Markus R, Macary, Paul A

“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by broad clinical manifestations including cardiovascular and renal…”
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Lovastatin Modulates Increased Cholesterol and Oxysterol Levels and Has a Neuroprotective Effect on Rat Hippocampal Neurons After Kainate Injury by He, Xin, Jenner, Andrew M, Ong, Wei-Yi, Farooqui, Akhlaq A, Patel, Shutish C

“…This study was carried out to elucidate the effect of a brain-permeable statin (lovastatin) on cholesterol and oxysterol levels of the hippocampus after…”
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The identification of antioxidants in dark soy sauce by Wang, Huansong, Jenner, Andrew M, Lee, Chung-Yung J, Shui, Guanghou, Tang, Soon Yew, Whiteman, Matthew, Wenk, Markus R, Halliwell, Barry

“…Soy sauce is a traditional fermented seasoning in Asian countries, that has high antioxidant activity in vitro and some antioxidant activity in vivo. We…”
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Cautions in the use of biomarkers of oxidative damage; the vascular and antioxidant effects of dark soy sauce in humans by Lee, Chung-Yung J., Isaac, Helen B., Wang, Huansong, Huang, Shan Hong, Long, Lee-Hua, Jenner, Andrew M., Kelly, Ronan P., Halliwell, Barry

“…Dark soy sauce (DSS) is a powerful antioxidant in vitro. We investigated whether this effect could occur in vivo and improve vascular function. Healthy human…”
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Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota by Lee, Hui Cheng, Jenner, Andrew M., Low, Chin Seng, Lee, Yuan Kun

“…Tea is rich in polyphenols and other phenolics that have been widely reported to have beneficial health effects. However, dietary polyphenols are not…”
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Correction: Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus by Jovanović, Vojislav, Abdul Aziz, Nurhuda, Lim, Yan Ting, Ng Ai Poh, Amanda, Jin Hui Chan, Sherlynn, Ho Xin Pei, Eliza, Lew, Fei Chuin, Shui, Guanghou, Jenner, Andrew M., Bowen, Li, McKinney, Eoin F., Lyons, Paul A., Kemeny, David M., Smith, Kenneth G. C., Wenk, Markus R., MacAry, Paul A.

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Elevated oxidative stress, iron accumulation around microvessels and increased 4-hydroxynonenal immunostaining in zone 1 of the liver acinus in hypercholesterolemic rabbits by Ong, Wei-Yi, Jenner, Andrew M, Pan, Ning, Ong, Choon-Nam, Halliwell, Barry

“…Rabbits were fed a diet containing 1% cholesterol for 8 weeks and the levels of iron and oxidized lipids in liver analysed using atomic absorption spectroscopy…”
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Analysis of sex steroids in human tears using LC-MS and GC-MS: Considerations and developments to improve method sensitivity and accuracy by Phan, Minh Anh Thu, Gibson, Emma, Golebiowski, Blanka, Stapleton, Fiona, Jenner, Andrew M., Bucknall, Martin P.

“…Sex steroids play a role in regulation of tear film function and may exert their action locally at the ocular surface. However, measurement of sex steroids in…”
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Apolipoprotein D modulates amyloid pathology in APP/PS1 Alzheimer's disease mice by Li, Hongyun, Ruberu, Kalani, Muñoz, Sonia Sanz, Jenner, Andrew M, Spiro, Adena, Zhao, Hua, Rassart, Eric, Sanchez, Diego, Ganfornina, Maria D, Karl, Tim, Garner, Brett

“…Abstract Apolipoprotein D (apoD) is expressed in the brain and levels are increased in affected brain regions in Alzheimer's disease (AD). The role that apoD…”
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Sterol Analysis by Quantitative Mass Spectrometry by Jenner, Andrew M, Brown, Simon H J

“…Analysis of sterols by mass spectrometry is a fundamental technique allowing for both qualitative and quantitative characterization of sterol molecular lipid…”
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Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample by Lee, Chung-Yung J., Huang, Shan Hong, Jenner, Andrew M., Halliwell, Barry

“…Oxidized lipids such as F2-isoprostanes (F2-IsoPs), hydroxyeicosatetraenoic acid products (HETEs), and cholesterol oxidation products (COPs) are widely…”
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