Search Results - "Jenne, Carleigh E."

Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation by Georgiou, Polymnia, Zanos, Panos, Jenne, Carleigh E, Gould, Todd D

“…Fluctuating hormone levels, such as estradiol might underlie the difference in the prevalence of psychiatric disorders observed in women vs. men. Estradiol…”
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Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor by Georgiou, Polymnia, Zanos, Panos, Mou, Ta-Chung M., An, Xiaoxian, Gerhard, Danielle M., Dryanovski, Dilyan I., Potter, Liam E., Highland, Jaclyn N., Jenne, Carleigh E., Stewart, Brent W., Pultorak, Katherine J., Yuan, Peixiong, Powels, Chris F., Lovett, Jacqueline, Pereira, Edna F. R., Clark, Sarah M., Tonelli, Leonardo H., Moaddel, Ruin, Zarate, Carlos A., Duman, Ronald S., Thompson, Scott M., Gould, Todd D.

“…We show that the sex of human experimenters affects mouse behaviors and responses following administration of the rapid-acting antidepressant ketamine and its…”
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Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function by Lumsden, Eric W., Troppoli, Timothy A., Myers, Scott J., Zanos, Panos, Aracava, Yasco, Kehr, Jan, Lovett, Jacqueline, Kim, Sukhan, Wang, Fu-Hua, Schmidt, Staffan, Jenne, Carleigh E., Yuan, Peixiong, Morris, Patrick J., Thomas, Craig J., Zarate, Carlos A., Moaddel, Ruin, Traynelis, Stephen F., Pereira, Edna F. R., Thompson, Scott M., Albuquerque, Edson X., Gould, Todd D.

“…Preclinical studies indicate that (2R,6R)-hydroxynorketamine (HNK) is a putative fast-acting antidepressant candidate. Although inhibition of NMDA-type…”
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(2R,6R)-hydroxynorketamine exerts mGlu₂ receptor-dependent antidepressant actions by Zanos, Panos, Highland, Jaclyn N., Stewart, Brent W., Georgiou, Polymnia, Jenne, Carleigh E., Lovett, Jacqueline, Morris, Patrick J., Thomas, Craig J., Moaddel, Ruin, Zarate, Carlos A., Gould, Todd D.

“…Currently approved antidepressant drugs often take months to take full effect, and ∼30% of depressed patients remain treatment resistant. In contrast,…”
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( 2R,6R )-hydroxynorketamine exerts mGlu 2 receptor-dependent antidepressant actions by Zanos, Panos, Highland, Jaclyn N, Stewart, Brent W, Georgiou, Polymnia, Jenne, Carleigh E, Lovett, Jacqueline, Morris, Patrick J, Thomas, Craig J, Moaddel, Ruin, Zarate, Jr, Carlos A, Gould, Todd D

“…Currently approved antidepressant drugs often take months to take full effect, and ∼30% of depressed patients remain treatment resistant. In contrast,…”
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