Search Results - "Jenkner, Carolin"
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The dentato-rubro-thalamic tract as the potential common deep brain stimulation target for tremor of various origin: an observational case series
Published in Acta neurochirurgica (01-05-2020)“…Introduction Deep brain stimulation alleviates tremor of various origins. The dentato-rubro-thalamic tract (DRT) has been suspected as a common tremor-reducing…”
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Modular-based psychotherapy (MoBa) versus cognitive–behavioural therapy (CBT) for patients with depression, comorbidities and a history of childhood maltreatment: study protocol for a randomised controlled feasibility trial
Published in BMJ open (12-07-2022)“…IntroductionIn depression treatment, most patients do not reach response or remission with current psychotherapeutic approaches. Major reasons for individual…”
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Tractography-assisted deep brain stimulation of the superolateral branch of the medial forebrain bundle (slMFB DBS) in major depression
Published in NeuroImage clinical (01-01-2018)“…Deep brain stimulation (DBS) of the superolateral branch of the medial forebrain bundle (slMFB) emerges as a - yet experimental - treatment for major…”
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Interpersonal Psychotherapy vs. Treatment as Usual for Major Depression Related to Work Stress: A Pilot Randomized Controlled Study
Published in Frontiers in psychiatry (18-03-2020)“…Depressive disorders are among the leading causes of sick leave and long-term work incapacity in most modern countries. Work related stress is described by…”
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Study Protocol for a Randomised Controlled Trial on Pulmonary Metastasectomy vs. Standard of Care in Colorectal Cancer Patients With ≥ 3 Lung Metastases (PUCC-Trial)
Published in Frontiers in oncology (11-07-2022)“…This is a multicentre prospective randomised controlled trial for patients with 3 or more resectable pulmonary metastases from colorectal carcinoma. The study…”
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ESCAschool study: trial protocol of an adaptive treatment approach for school-age children with ADHD including two randomised trials
Published in BMC psychiatry (24-07-2017)“…The ESCAschool study addresses the treatment of school-age children with attention-deficit/hyperactivity disorder (ADHD) in a large multicentre trial. It aims…”
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Stereotactic cisternal lavage in patients with aneurysmal subarachnoid hemorrhage with urokinase and nimodipine for the prevention of secondary brain injury (SPLASH): study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (15-04-2021)“…Delayed cerebral infarction (DCI) is a major cause of death and poor neurological outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH). Direct…”
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Individualised short-term therapy for adolescents impaired by attention-deficit/hyperactivity disorder despite previous routine care treatment (ESCAadol)-Study protocol of a randomised controlled trial within the consortium ESCAlife
Published in Current controlled trials in cardiovascular medicine (27-04-2018)“…Despite the high persistence rate of attention-deficit/hyperactivity disorder (ADHD) throughout the lifespan, there is a considerable gap in knowledge…”
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Unravelling delayed therapy escape after thalamic deep brain stimulation for essential tremor? – Additional clinical and neuroimaging evidence
Published in NeuroImage clinical (01-01-2022)“…•Rebound tremor frequency seems to be a good diagnostic marker for delayed therapy escape.•Ataxia seems to play a major role in delayed therapy escape.•Therapy…”
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Individualised stepwise adaptive treatment for 3-6-year-old preschool children impaired by attention-deficit/hyperactivity disorder (ESCApreschool): study protocol of an adaptive intervention study including two randomised controlled trials within the consortium ESCAlife
Published in Current controlled trials in cardiovascular medicine (09-01-2020)“…Attention-deficit/hyperactivity disorder (ADHD) is a psychosocially impairing and cost-intensive mental disorder, with first symptoms occurring in early…”
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ESCAlate - Adaptive treatment approach for adolescents and adults with ADHD: study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (18-05-2018)“…Over the last decade, a wide range of attention-deficit/hyperactivity disorder (ADHD) treatment approaches for adults, including both pharmacological…”
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Modeling Variables With a Spike at Zero: Examples and Practical Recommendations
Published in American journal of epidemiology (15-04-2017)“…In most epidemiologic studies and in clinical research generally, there are variables with a spike at zero, namely variables for which a proportion of…”
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Algorithm‐based modular psychotherapy vs. cognitive‐behavioral therapy for patients with depression, psychiatric comorbidities and early trauma: a proof‐of‐concept randomized controlled trial
Published in World psychiatry (01-06-2024)“…Effect sizes of psychotherapies currently stagnate at a low‐to‐moderate level. Personalizing psychotherapy by algorithm‐based modular procedures…”
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STRengthening Analytical Thinking for Observational Studies: the STRATOS initiative
Published in Statistics in medicine (30-12-2014)“…The validity and practical utility of observational medical research depends critically on good study design, excellent data quality, appropriate statistical…”
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PSMA-PET/MRI-Based Focal Dose Escalation in Patients with Primary Prostate Cancer Treated with Stereotactic Body Radiation Therapy (HypoFocal-SBRT): Study Protocol of a Randomized, Multicentric Phase III Trial
Published in Cancers (18-11-2021)“…Technical advances in radiotherapy (RT) treatment planning and delivery have substantially changed RT concepts for primary prostate cancer (PCa) by (i)…”
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Modeling continuous covariates with a "spike" at zero: Bivariate approaches
Published in Biometrical journal (01-07-2016)“…In epidemiology and clinical research, predictors often take value zero for a large amount of observations while the distribution of the remaining observations…”
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Combination of CT angiography and MRI in surgical planning of deep brain stimulation
Published in Neuroradiology (01-11-2018)“…Purpose For safe deep brain stimulation (DBS) planning, an accurate visualization and localization of vessels is mandatory. Contrast enhanced (ce) MRI depicts…”
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Long-term improvement of quality of life in adult ADHD - results of the randomized multimodal COMPAS trial
Published in International journal of mental health (03-07-2021)“…Attention Deficit Hyperactivity Disorder (ADHD) negatively impacts Quality of Life (QoL) in adults. Earlier studies on pharmacological treatment have shown…”
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One Pass Thalamic and Subthalamic Stimulation for Patients with Tremor-Dominant Idiopathic Parkinson Syndrome (OPINION): Protocol for a Randomized, Active-Controlled, Double-Blinded Pilot Trial
Published in JMIR research protocols (30-01-2018)“…Besides fluctuations, therapy refractory tremor is one of the main indications of deep brain stimulation (DBS) in patients with idiopathic Parkinson syndrome…”
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Deep Brain Stimulation for Tremor Tractographic Versus Traditional (DISTINCT): Study Protocol of a Randomized Controlled Feasibility Trial
Published in JMIR research protocols (22-12-2016)“…Essential tremor is a movement disorder that can result in profound disability affecting the quality of life. Medically refractory essential tremor can be…”
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