Search Results - "Jenkins, Matthew C"
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Encapsulin Nanocontainers as Versatile Scaffolds for the Development of Artificial Metabolons
Published in ACS synthetic biology (16-04-2021)“…The construction of non-native biosynthetic pathways represents a powerful, modular strategy for the production of valuable synthons and fine chemicals…”
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Journal Article -
2
Combined holographic-mechanical optical tweezers: construction, optimization, and calibration
Published in Review of scientific instruments (01-08-2009)“…A spatial light modulator (SLM) and a pair of galvanometer-mounted mirrors (GMM) were combined into an optical tweezers setup. This provides great flexibility…”
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Journal Article -
3
Modular Catalysis: Aptamer Enhancement of Enzyme Kinetics in a Nanoparticle Reactor
Published in Biomacromolecules (10-04-2023)“…Enzyme activity requires sequential binding and chemical transformation of substrates. While directed evolution and random mutagenesis are common methods for…”
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Journal Article -
4
Heterologous Prime-Boost with Immunologically Orthogonal Protein Nanoparticles for Peptide Immunofocusing
Published in ACS nano (23-07-2024)“…Protein nanoparticles are effective platforms for antigen presentation and targeting effector immune cells in vaccine development. Encapsulins are a class of…”
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Journal Article -
5
Sequential Two-Photon Delayed Fluorescence Anisotropy for Macromolecular Size Determination
Published in The journal of physical chemistry. B (04-05-2023)“…Time-resolved fluorescence anisotropy (FA) uses the fluorophore depolarization rate to report on rotational diffusion, conformation changes, and intermolecular…”
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Journal Article -
6
Biophysics-Guided Lead Discovery of HBV Capsid Assembly Modifiers
Published in ACS infectious diseases (12-04-2024)“…Hepatitis B virus (HBV) is the leading cause of chronic liver pathologies worldwide. HBV nucleocapsid, a key structural component, is formed through the…”
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7
Protein Engineering of Encapsulin Nanocontainers for Biocatalysis Applications
Published 01-01-2020“…Nature has been shown to repeatedly employ proteinaceous containers spanning a broad range of length scales (i.e. approximately 10 to >2000 nm) to suit myriad…”
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Dissertation -
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Colloidal suspensions in modulated light fields
Published 19-06-2008“…Periodically-modulated potentials in the form of light fields have previously been applied to induce reversible phase transitions in dilute colloidal systems…”
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Journal Article -
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Confocal microscopy of colloidal particles: towards reliable, optimum coordinates
Published 26-09-2007“…Over the last decade, the light microscope has become increasingly useful as a quantitative tool for studying colloidal systems. The ability to obtain particle…”
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Journal Article -
10
Combined holographic-mechanical optical tweezers: Construction, optimisation and calibration
Published 21-03-2009“…A spatial light modulator (SLM) and a pair of galvanometer-mounted mirrors (GMM) were combined into an optical tweezers set-up. This provides great flexibility…”
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Journal Article -
11
Finding bridges in packings of colloidal spheres
Published 17-06-2010“…We identify putative load-bearing structures (bridges) in experimental colloidal systems studied by confocal microscopy. Bridges are co-operative structures…”
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Journal Article