Search Results - "Jenkins, MK"

IN VIVO ACTIVATION OF ANTIGEN-SPECIFIC CD4 T CELLS by Jenkins, Marc K, Khoruts, Alexander, Ingulli, Elizabeth, Mueller, Daniel L, McSorley, Stephen J, Reinhardt, R. Lee, Itano, Andrea, Pape, Kathryn A

“…Physical detection of antigen-specific CD4 T cells has revealed features of the in vivo immune response that were not appreciated from in vitro studies. In…”
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Origins of CD4+ effector and central memory T cells by Pepper, Marion, Jenkins, Marc K

“…Lineage-committed effector CD4 + T cells are generated at the peak of the primary response and are followed by heterogeneous populations of central and…”
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Naïve and Memory CD4⁺ T Cell Survival Controlled by Clonal Abundance by Hataye, Jason, Moon, James J., Khoruts, Alexander, Reilly, Cavan, Jenkins, Marc K.

“…Immunity to a plethora of microbes depends on a diverse repertoire of $na\ddot{i}ve$ lymphocytes and the production of long-lived memory cells. We present…”
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Antigen presentation to naive CD4 T cells in the lymph node by Jenkins, Marc K, Itano, Andrea A

“…Although the presentation of peptide-major histocompatibility complex class II (pMHC class II) complexes to CD4 T cells has been studied extensively in vitro,…”
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Visualizing the generation of memory CD4 T cells in the whole body by Jenkins, Marc K, Reinhardt, R. Lee, Khoruts, Alexander, Merica, Rebecca, Zell, Traci

“…It is thought that immunity depends on naïve CD4 T cells that proliferate in response to microbial antigens, differentiate into memory cells that produce…”
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Distinct Dendritic Cell Populations Sequentially Present Antigen to CD4 T Cells and Stimulate Different Aspects of Cell-Mediated Immunity by Itano, Andrea A, McSorley, Stephen J, Reinhardt, R.Lee, Ehst, Benjamin D, Ingulli, Elizabeth, Rudensky, Alexander Y, Jenkins, Marc K

“…Peptide:MHC II complexes derived from a fluorescent antigen were detected in vivo to identify the cells that present subcutaneously injected antigen to CD4 T…”
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Development of a Novel Transgenic Mouse for the Study of Interactions Between CD4 and CD8 T Cells During Graft Rejection by Ehst, Benjamin D., Ingulli, Elizabeth, Jenkins, Marc K.

“…The goal of this study was the development of a system in which the cooperative interactions between CD4 and CD8 T cells specific for defined peptides from a…”
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CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells by Catron, Drew M, Rusch, Lori K, Hataye, Jason, Itano, Andrea A, Jenkins, Marc K

“…We explored the relationship between the time of naive CD4+ T cell exposure to antigen in the primary immune response and the quality of the memory cells…”
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Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse by Taylor, J.J., Laudenbach, M., Tucker, A.M., Jenkins, M.K., Pravetoni, M.

“…Vaccination against drugs of abuse shows efficacy in animal models, yet few subjects achieve effective serum antibody titers in clinical studies. A barrier to…”
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In vivo detection of dendritic cell antigen presentation to CD4(+) T cells by Ingulli, E, Mondino, A, Khoruts, A, Jenkins, M K

“…Although lymphoid dendritic cells (DC) are thought to play an essential role in T cell activation, the initial physical interaction between antigen-bearing DC…”
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Visualizing the First 50 Hr of the Primary Immune Response to a Soluble Antigen by Catron, Drew M., Itano, Andrea A., Pape, Kathryn A., Mueller, Daniel L., Jenkins, Marc K.

“…Recently, static and dynamic imaging methods have produced the first glimpses of the interactions between antigen-specific T cells and peptide-MHC-bearing…”
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Tracking Salmonella-Specific CD4 T Cells In Vivo Reveals a Local Mucosal Response to a Disseminated Infection by McSorley, Stephen J., Asch, Sarah, Costalonga, Massimo, Reinhardt, R.Lee, Jenkins, Marc K.

“…A novel adoptive transfer system was used to track the fate of naive Salmonella-specific CD4 T cells in vivo. These cells showed signs of activation in the…”
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Visualization of Specific B and T Lymphocyte Interactions in the Lymph Node by Garside, Paul, Ingulli, Elizabeth, Merica, Rebecca R., Johnson, Julia G., Noelle, Randolph J., Jenkins, Marc K.

“…Early events in the humoral immune response were visualized in lymph nodes by simultaneous tracking of antigen-specific CD4 T and B cells after immunization…”
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Inflammatory Cytokines Provide a Third Signal for Activation of Naive CD4+ and CD8+ T Cells by Curtsinger, Julie M, Schmidt, Clint S, Mondino, Anna, Lins, Debra C, Kedl, Ross M, Jenkins, Marc K, Mescher, Matthew F

“…The effects of inflammatory cytokines on naive T cells have been studied using MHC protein/peptide complexes on microspheres, thus avoiding the use of APCs…”
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The ups and downs of T cell costimulation by Jenkins, M K

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Antibody is required for protection against virulent but not attenuated Salmonella enterica serovar typhimurium by MCSORLEY, S. J, JENKINS, M. K

“…Resolution of infection with attenuated Salmonella is an active process that requires CD4(+) T cells. Here, we demonstrate that costimulation via the surface…”
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Characterization of CD4+ T Cell Responses During Natural Infection with Salmonella typhimurium by McSorley, Stephen J, Cookson, Brad T, Jenkins, Marc K

“…CD4+ T cells are important for resistance to infection with Salmonella typhimurium. However, the Ag specificity of this T cell response is unknown. Here, we…”
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Tracking immune responses in vivo by Jenkins, MK

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Cell and receptor requirements for streptococcal pyrogenic exotoxin T-cell mitogenicity by LEONARD, B. A. B, LEE, P. K, JENKINS, M. K, SCHLIEVERT, P. M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation by Reinhardt, R Lee, Bullard, Daniel C, Weaver, Casey T, Jenkins, Marc K

“…The migration of antigen-specific T cells to nonlymphoid tissues is thought to be important for the elimination of foreign antigens from the body. However,…”
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