Search Results - "Jenkins, Christopher A"

Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species by Lowe, Robert, Barton, Carl, Jenkins, Christopher A, Ernst, Christina, Forman, Oliver, Fernandez-Twinn, Denise S, Bock, Christoph, Rossiter, Stephen J, Faulkes, Chris G, Ozanne, Susan E, Walter, Lutz, Odom, Duncan T, Mellersh, Cathryn, Rakyan, Vardhman K

“…Mammalian species exhibit a wide range of lifespans. To date, a robust and dynamic molecular readout of these lifespan differences has not yet been identified…”
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Characterisation of canine KCNIP4: A novel gene for cerebellar ataxia identified by whole-genome sequencing two affected Norwegian Buhund dogs by Jenkins, Christopher A, Kalmar, Lajos, Matiasek, Kaspar, Mari, Lorenzo, Kyöstilä, Kaisa, Lohi, Hannes, Schofield, Ellen C, Mellersh, Cathryn S, De Risio, Luisa, Ricketts, Sally L

“…A form of hereditary cerebellar ataxia has recently been described in the Norwegian Buhund dog breed. This study aimed to identify the genetic cause of the…”
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An Inversion Disrupting FAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed by Forman, Oliver P, Hitti, Rebekkah J, Pettitt, Louise, Jenkins, Christopher A, O'Brien, Dennis P, Shelton, G Diane, De Risio, Luisa, Quintana, Rodrigo Gutierrez, Beltran, Elsa, Mellersh, Cathryn

“…Sensory neuropathy in the Border Collie is a severe neurological disorder caused by the degeneration of sensory and, to a lesser extent, motor nerve cells with…”
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A preliminary genome‐wide association study of paroxysmal dyskinesia in the Norwich Terrier by Jenkins, Christopher A., De Risio, Luisa, Dietschi, Elisabeth, Leeb, Tosso, Rytz, Ulrich, Schawalder, Peter, Schoenebeck, Jeffrey J., Mellersh, Cathryn S., Ricketts, Sally L.

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Phenotypic Effects of FGF4 Retrogenes on Intervertebral Disc Disease in Dogs by Batcher, Kevin, Dickinson, Peter, Giuffrida, Michelle, Sturges, Beverly, Vernau, Karen, Knipe, Marguerite, Rasouliha, Sheida Hadji, Drögemüller, Cord, Leeb, Tosso, Maciejczyk, Kimberly, Jenkins, Christopher A, Mellersh, Cathryn, Bannasch, Danika

“…Two retrogenes on chromosomes 12 (12- RG) and 18 (18- RG) contribute to short-limbed phenotypes in dogs. 12- RG has also been associated with intervertebral…”
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Hereditary ataxia in four related Norwegian Buhunds by Mari, Lorenzo, Matiasek, Kaspar, Jenkins, Christopher A, De Stefani, Alberta, Ricketts, Sally L, Forman, Oliver, De Risio, Luisa

“…CASE DESCRIPTION Two 12-week-old Norwegian Buhunds from a litter of 5 were evaluated because of slowly progressive cerebellar ataxia and fine head tremors. Two…”
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Evaluation of ADAMTS17 in Chinese Shar-Pei with primary open-angle glaucoma, primary lens luxation, or both by Oliver, James A C, Rustidge, Sophie, Pettitt, Louise, Jenkins, Christopher A, Farias, Fabiana H G, Giuliano, Elizabeth A, Mellersh, Cathryn S

“…OBJECTIVE To evaluate the coding regions of ADAMTS17 for potential mutations in Chinese Shar-Pei with a diagnosis of primary open-angle glaucoma (POAG),…”
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Improving the resolution of canine genome‐wide association studies using genotype imputation: A study of two breeds by Jenkins, Christopher A., Schofield, Ellen C., Mellersh, Cathryn S., De Risio, Luisa, Ricketts, Sally L

“…Summary Genotype imputation using a reference panel that combines high‐density array data and publicly available whole genome sequence consortium variant data…”
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A novel locus on canine chromosome 13 is associated with cataract in the Australian Shepherd breed of domestic dog by Ricketts, Sally L., Pettitt, Louise, McLaughlin, Bryan, Jenkins, Christopher A., Mellersh, Cathryn S.

“…Hereditary cataract is a common ocular disorder in the purebred dog population and is a leading cause of visual impairment and blindness in dogs. Despite this,…”
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Comparison of canine mandibular bone regeneration by distraction osteogenesis versus acute resection and rigid external fixation by Gosain, Arun K, Kalantarian, Behrooz, Song, Lian Shen, Larson, Jeffrey D, Jenkins, Christopher A, Wilson, Charles R

“…The present study was performed (1) to explore the mechanism of skeletal healing following distraction osteogenesis of the mandible and to evaluate whether the…”
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Genome sequencing reveals a splice donor site mutation in the SNX14 gene associated with a novel cerebellar cortical degeneration in the Hungarian Vizsla dog breed by Fenn, Joe, Boursnell, Mike, Hitti, Rebekkah J, Jenkins, Christopher A, Terry, Rebecca L, Priestnall, Simon L, Kenny, Patrick J, Mellersh, Cathryn S, Forman, Oliver P

“…Cerebellar cortical degeneration (CCD) is an increasingly recognised neurodegenerative disease process affecting many dog breeds. Typical presentation consists…”
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Genetic Investigations of Canine Idiopathic Epilepsy and Movement Disorders by Jenkins, Christopher A

“…Dogs represent a fascinating species with dramatic variation in traits across hundreds of breeds. Genetic bottlenecks, inbreeding, and selection for extreme…”
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Identification of a novel frameshift mutation in the DMD gene as the cause of muscular dystrophy in a Norfolk terrier dog by Jenkins, Christopher A, Forman, Oliver P

“…A Norfolk terrier was referred to the Animal Health Trust neurology department with suspected dystrophin-deficient muscular dystrophy (DD-MD), which was…”
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Comparison of canine mandibular bone regeneration by distraction osteogenesis versus acute resection and rigid external fixation. Discussion by GOSAIN, Arun K, KALANTARIAN, Behrooz, LIAN SHEN SONG, LARSON, Jeffrey D, JENKINS, Christopher A, WILSON, Charles R, HOLLIER, Lorry

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