Search Results - "Jenkins, Brittany"
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Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor
Published in The American journal of pathology (01-05-2018)“…Interactions between the gut microbiota and the host are important for health, where dysbiosis has emerged as a likely component of mucosal disease. The…”
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Amino Acid Trp: The Far Out Impacts of Host and Commensal Tryptophan Metabolism
Published in Frontiers in immunology (04-06-2021)“…Tryptophan (Trp) is an essential amino acid primarily derived from the diet for use by the host for protein synthesis. The intestinal tract is lined with…”
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The 2019 US medical genetics workforce: a focus on clinical genetics
Published in Genetics in medicine (01-08-2021)“…This study characterizes the US clinical genetics workforce to inform workforce planning and public policy development. A 32-question survey was electronically…”
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Stress and success: Individual differences in the glucocorticoid stress response predict behavior and reproductive success under high predation risk
Published in Hormones and behavior (01-11-2014)“…A fundamental element of how vertebrates respond to stressors is by rapidly elevating circulating glucocorticoid hormones. Individual variation in the…”
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An experimental analysis of the heritability of variation in glucocorticoid concentrations in a wild avian population
Published in Proceedings of the Royal Society. B, Biological sciences (07-09-2014)“…Glucocorticoid hormones (CORT) are predicted to promote adaptation to variable environments, yet little is known about the potential for CORT secretion…”
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Atypical Chemokine Receptor 1 ( DARC/ACKR1 ) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African Ancestry
Published in Cancer epidemiology, biomarkers & prevention (01-04-2019)“…Tumor-specific immune response is an important aspect of disease prognosis and ultimately impacts treatment decisions for innovative immunotherapies. The…”
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7
Label-free ferrohydrodynamic cell separation of circulating tumor cells
Published in Lab on a chip (12-09-2017)“…Circulating tumor cells (CTCs) have significant implications in both basic cancer research and clinical applications. To address the limited availability of…”
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Tumor antigen-independent and cell size variation-inclusive enrichment of viable circulating tumor cells
Published in Lab on a chip (14-05-2019)“…Isolation of circulating tumor cells (CTCs) from blood provides a minimally-invasive alternative for basic understanding, diagnosis, and prognosis of…”
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Risk factors for breast cancer subtypes by race and ethnicity: A scoping review
Published in JNCI : Journal of the National Cancer Institute (17-07-2024)“…Breast cancer is comprised of distinct molecular subtypes. Studies have reported differences in risk factor associations with breast cancer subtypes,…”
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Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
Published in Clinical cancer research (15-04-2020)“…Compared with their European American (EA) counterparts, African American (AA) women are more likely to die from breast cancer in the United States. This…”
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The maintenance of phenotypic divergence through sexual selection: An experimental study in barn swallows Hirundo rustica
Published in Evolution (01-09-2016)“…Previous studies have shown that sexual signals can rapidly diverge among closely related species. However, we lack experimental studies to demonstrate that…”
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Signaling stress? An analysis of phaeomelanin-based plumage color and individual corticosterone levels at two temporal scales in North American barn swallows, Hirundo rustica erythrogaster
Published in Hormones and behavior (01-09-2013)“…Sexually selected traits confer greater reproductive benefits to individuals with more elaborate forms of the signal. However, whether these signals convey…”
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13
Loss of interleukin‐10 receptor disrupts intestinal epithelial cell proliferation and skews differentiation towards the goblet cell fate
Published in The FASEB journal (01-06-2021)“…Intestinal epithelial cells (IEC) are crucial for maintaining proper digestion and overall homeostasis of the gut mucosa. IEC proliferation and differentiation…”
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14
AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells
Published in Journal of cellular physiology (01-01-2018)“…More than 40% of patients with luminal breast cancer treated with endocrine therapy agent tamoxifen demonstrate resistance. Emerging evidence suggests tumor…”
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Investigation of triple-negative breast cancer risk alleles in an International African-enriched cohort
Published in Scientific reports (29-04-2021)“…Large-scale efforts to identify breast cancer (BC) risk alleles have historically taken place among women of European ancestry. Recently, there are new efforts…”
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Quantitative genetics of plumage color: lifetime effects of early nest environment on a colorful sexual signal
Published in Ecology and evolution (01-08-2015)“…Phenotypic differences among individuals are often linked to differential survival and mating success. Quantifying the relative influence of genetic and…”
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Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland
Published in PloS one (22-01-2016)“…Peptidylarginine deiminases (PADs) post-translationally convert arginine into neutral citrulline residues. Our past work shows that PADs are expressed in the…”
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An experimental test of the effect of brood size on glucocorticoid responses, parental investment, and offspring phenotype
Published in General and comparative endocrinology (01-06-2017)“…Highlights • Brood value had no effect on maternal glucocorticoid responses. • Females tending enlarged broods increased investment only under some contexts. •…”
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Neighborhood Deprivation and DNA Methylation and Expression of Cancer Genes in Breast Tumors
Published in JAMA network open (01-11-2023)“…The biological processes that underlie the association of neighborhood environment with chronic diseases, such as cancer, remain poorly understood. To…”
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Neighborhood Socioeconomic Disadvantage Across the Life Course and Premature Mortality
Published in JAMA network open (01-08-2024)“…There are consistent data demonstrating that socioeconomic disadvantage is associated with risk of premature mortality, but research on the relationship…”
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