Search Results - "Jenkins, B. R."

Efficacy of Bilateral Prophylactic Mastectomy in BRCA1 and BRCA2 Gene Mutation Carriers by Hartmann, Lynn C., Sellers, Thomas A., Schaid, Daniel J., Frank, Thomas S., Soderberg, Cheryl L., Sitta, Diana L., Frost, Marlene H., Grant, Clive S., Donohue, John H., Woods, John E., McDonnell, Shannon K., Vockley, Catherine Walsh, Deffenbaugh, Amie, Couch, Fergus J., Jenkins, Robert B.

“…Background: In women with a family history of breast cancer, bilateral prophylactic mastectomy is associated with a decreased risk of subsequent breast cancer…”
Get full text

Concordance Between Local and Central Laboratory HER2 Testing in the Breast Intergroup Trial N9831 by Roche, Patrick C., Suman, Vera J., Jenkins, Robert B., Davidson, Nancy E., Martino, Silvana, Kaufman, Peter A., Addo, Ferdinand K., Murphy, Bronagh, Ingle, James N., Perez, Edith A.

“…The efficacy of trastuzumab for metastases coupled with the relatively poor prognosis of patients with node-positive, HER2-positive breast cancer has led to…”
Get full text

Discrepancies in Clinical Laboratory Testing of Eligibility for Trastuzumab Therapy: Apparent Immunohistochemical False-Positives Do Not Get the Message by TUBBS, R. R, PETTAY, J. D, ROCHE, P. C, STOLER, M. H, JENKINS, R. B, GROGAN, T. M

“…Several studies have reported what seem to be false-positive results using the Food and Drug Administration (FDA)-approved HercepTest (Dako Corp, Carpinteria,…”
Get full text

Patterns and ecological predictors of age-related performance in female North American barn swallows, Hirundo rustica erythrogaster by Bradley, R. J, Hubbard, J. K, Jenkins, B. R, Safran, R. J

“…Life history theory describes the optimization of important trade-offs within an individual’s lifetime and predicts that an individual’s reproductive…”
Get full text

A genomic classifier predicting metastatic disease progression in men with biochemical recurrence after prostatectomy by Ross, A E, Feng, F Y, Ghadessi, M, Erho, N, Crisan, A, Buerki, C, Sundi, D, Mitra, A P, Vergara, I A, Thompson, D J S, Triche, T J, Davicioni, E, Bergstralh, E J, Jenkins, R B, Karnes, R J, Schaeffer, E M

“…Background: Due to their varied outcomes, men with biochemical recurrence (BCR) following radical prostatectomy (RP) present a management dilemma. Here, we…”
Get full text

Transformation of low grade glioma and correlation with outcome: an NCCTG database analysis by Jaeckle, K. A., Decker, P. A., Ballman, K. V., Flynn, P. J., Giannini, C., Scheithauer, B. W., Jenkins, R. B., Buckner, J. C.

“…Glioblastomas (GBM) may originate de novo (primary), or following transformation from a lower grade glioma (secondary), and it has been postulated that these…”
Get full text

Clinical Significance of Alterations of Chromosome 8 in High-Grade, Advanced,Nonmetastatic Prostate Carcinoma by Sato, Kazunari, Qian, Junqi, Slezak, Jeffrey M., Lieber, Michael M., Bostwick, David G., Bergstralh, Erik J., Jenkins, Robert B.

“…BACKGROUND: Chromosome 8 alterations, including loss of 8p21-22 and gain of 8q24, are commonly observed in prostate carcinoma. We examined whether these…”
Get full text

PTEN Mutation, EGFR Amplification, and Outcome in Patients With Anaplastic Astrocytoma and Glioblastoma Multiforme by Smith, Justin S., Tachibana, Issei, Passe, Sandra M., Huntley, Brenda K., Borell, Thomas J., Iturria, Nancy, O'Fallon, Judith R., Schaefer, Paul L., Scheithauer, Bernd W., James, C. David, Buckner, Jan C., Jenkins, Robert B.

“…Background: Survival of patients with anaplastic astrocytoma is highly variable. Prognostic markers would thus be useful to identify clinical subsets of such…”
Get full text

Alterations of Chromosome Arms 1p and 19q as Predictors of Survival in Oligodendrogliomas, Astrocytomas, and Mixed Oligoastrocytomas by SMITH, J. S, PERRY, A, JENKINS, R. B, BORELL, T. J, LEE, H. K, O'FALLON, J, HOSEK, S. M, KIMMEL, D, YATES, A, BURGER, P. C, SCHEITHAUER, B. W

“…A recent report suggests that alterations of chromosome arms 1p and 19q are associated with chemotherapeutic response and overall survival in anaplastic…”
Get full text

Efficacy of Bilateral Prophylactic Mastectomy in Women with a Family History of Breast Cancer by Hartmann, Lynn C, Schaid, Daniel J, Woods, John E, Crotty, Thomas P, Myers, Jeffrey L, Arnold, P.G, Petty, Paul M, Sellers, Thomas A, Johnson, Joanne L, McDonnell, Shannon K, Frost, Marlene H, Grant, Clive S, Michels, Virginia V, Jenkins, Robert B

“…The availability of improved means to identify women at high risk for breast cancer, such as genetic testing for BRCA1 and BRCA2 mutations, intensifies the…”
Get full text

Sporadic medulloblastomas contain PTCH mutations by RAFFEL, C, JENKINS, R. B, FREDERICK, L, HEBRINK, D, ALDERETE, B, FULTS, D. W, JAMES, C. D

“…Nevoid basal cell carcinoma syndrome (NBCCS), or Gorlin's syndrome, is an autosomal dominant disorder that predisposes to developmental defects and various…”
Get full text

Efficacy of Contralateral Prophylactic Mastectomy in Women With a Personal and Family History of Breast Cancer by MCDONNELL, Shannon K, SCHAID, Daniel J, CROTTY, Thomas B, JENKINS, Robert B, SELLERS, Thomas A, HARTMANN, Lynn C, MYERS, Jeffrey L, GRANT, Clive S, DONOHUE, John H, WOODS, John E, FROST, Marlene H, JOHNSON, Joanne L, SITTA, Diana L, SLEZAK, Jeffrey M

“…To estimate the efficacy of contralateral prophylactic mastectomy in women with a personal and family history of breast cancer. We followed the course of 745…”
Get full text

Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype by SMITH, J. S, ALDERETE, B, FEUERSTEIN, B. G, BURGER, P. C, SCHEITHAUER, B. W, JENKINS, R. B, MINN, Y, BORELL, T. J, PERRY, A, MOHAPATRA, G, HOSEK, S. M, KIMMEL, D, O'FALLON, J, YATES, A

“…Allelic alterations of chromosomes 1 and 19 are frequent events in human diffuse gliomas and have recently proven to be strong predictors of chemotherapeutic…”
Get full text

Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization by JENKINS, R. B, QIAN, J, LIEBER, M. M, BOSTWICK, D. G

“…The role of c-myc in prostatic carcinogenesis is poorly understood. The pathogenetic relationship between high-grade prostatic intraepithelial neoplasia (PIN),…”
Get full text

Long-term Satisfaction and Psychological and Social Function Following Bilateral Prophylactic Mastectomy by Frost, Marlene H, Schaid, Daniel J, Sellers, Thomas A, Slezak, Jeffrey M, Arnold, Phillip G, Woods, John E, Petty, Paul M, Johnson, Joanne L, Sitta, Diana L, McDonnell, Shannon K, Rummans, Teresa A, Jenkins, Robert B, Sloan, Jeff A, Hartmann, Lynn C

“…CONTEXT Prophylactic mastectomy is a preventive option for women who wish to reduce their risk of breast cancer. There has been concern about possible negative…”
Get full text

Genetically Defined Oligodendroglioma Is Characterized by Indistinct Tumor Borders at MRI by Johnson, D R, Diehn, F E, Giannini, C, Jenkins, R B, Jenkins, S M, Parney, I F, Kaufmann, T J

“…In 2016, the World Health Organization revised the brain tumor classification, making mutation and 1p/19q codeletion the defining features of…”
Get full text

Human epithelial ovarian cancer allelotype by CLIBY, W, RITLAND, S, HARTMANN, L, DODSON, M, HALLING, K. C, KEENEY, G, PODRATZ, K. C, JENKINS, R. B

“…To determine which chromosomes and chromosomal regions contain putative tumor suppressor genes important for human epithelial ovarian cancer, we performed loss…”
Get full text

Clinical outcome of gliosarcoma compared with glioblastoma multiforme : North Central Cancer Treatment Group results by GALANIS, E, BUCKNER, J. C, DINAPOLI, R. P, SCHEITHAUER, B. W, JENKINS, R. B, CHIAO HUA WANG, O'FALLON, J. R, FARR, G. JR

“…Gliosarcoma, a rare malignancy of the central nervous system, consists of gliomatous and sarcomatous elements. There are conflicting reports regarding its…”
Get full text

Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality by Tse, B W C, Volpert, M, Ratther, E, Stylianou, N, Nouri, M, McGowan, K, Lehman, M L, McPherson, S J, Roshan-Moniri, M, Butler, M S, Caradec, J, Gregory-Evans, C Y, McGovern, J, Das, R, Takhar, M, Erho, N, Alshalafa, M, Davicioni, E, Schaeffer, E M, Jenkins, R B, Ross, A E, Karnes, R J, Den, R B, Fazli, L, Gregory, P A, Gleave, M E, Williams, E D, Rennie, P S, Buttyan, R, Gunter, J H, Selth, L A, Russell, P J, Nelson, C C, Hollier, B G

“…Recent evidence has implicated the transmembrane co-receptor neuropilin-1 (NRP1) in cancer progression. Primarily known as a regulator of neuronal guidance and…”
Get full text

PTEN/MMAC1 mutations and EGFR amplification in glioblastomas by LIU, W, JAMES, C. D, FREDERICK, L, ALDERETE, B. E, JENKINS, R. B

“…Loss of heterozygosity (LOH) from chromosome 10 is a hallmark of glioblastoma, the most malignant (grade IV) form of glioma. A candidate tumor suppressor gene,…”
Get full text