Search Results - "Jenjak, Shawn"
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Development and validation of a purification system for functional full-length human SR-B1 and CD36
Published in The Journal of biological chemistry (01-10-2023)“…Scavenger receptor class B type 1 (SR-B1) and CD36 are both members of the class B scavenger receptor family that play important roles in lipoprotein…”
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A Tale of Two Scavenger Receptors: Structure‐Function Relationships of Purified SR‐B1 and CD36
Published in The FASEB journal (01-05-2022)“…Both CD36 and SR‐B1 are glycosylated integral membrane proteins belonging to the class B scavenger receptor family and are known to play roles in…”
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Abstract 119: Into The Wormhole: Understanding SR-B1’s Cholesterol Transport Functions Through Structural Studies
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2022)“…Scavenger receptor Class B type 1 (SR-B1) is a glycosylated integral membrane protein that serves as the primary receptor for high density lipoprotein (HDL)…”
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Abstract 206: Into The Wormhole: Understanding SR-B1’s Cholesterol Transport Functions Through Structural Studies
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2022)“…Scavenger receptor Class B type 1 (SR-B1) is a glycosylated integral membrane protein that serves as the primary receptor for high density lipoprotein (HDL)…”
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Developing a Purification System to Assess SR‐BI Structure and Function
Published in The FASEB journal (01-05-2021)“…High density lipoprotein (HDL) is considered anti‐atherogenic due to its ability to remove cholesterol from the periphery and deliver it to the liver via its…”
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Abstract P115: Building A Structurally Sound System To Understand SR-BI Function
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2021)“…Abstract only The interaction of scavenger receptor BI (SR-BI) and high density lipoproteins (HDL) is the key step for the bodily removal of cholesterol. The…”
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Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor
Published in Science (American Association for the Advancement of Science) (08-07-2022)“…G protein-coupled receptors (GPCRs) recruit β-arrestins to coordinate diverse cellular processes, but the structural dynamics driving this process are poorly…”
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