Search Results - "Jeneson, Jeroen"
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Exercise MR of Skeletal Muscles, the Heart, and the Brain
Published in Journal of magnetic resonance imaging (10-05-2024)“…Magnetic resonance (MR) imaging (MRI) is routinely used to evaluate organ morphology and pathology in the human body at rest or in combination with…”
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Magnetic resonance reveals mitochondrial dysfunction and muscle remodelling in spinal muscular atrophy
Published in Brain (London, England : 1878) (24-05-2022)“…Genetic therapy has changed the prognosis of hereditary proximal spinal muscular atrophy, although treatment efficacy has been variable. There is a clear need…”
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Doxorubicin‐induced skeletal muscle atrophy: Elucidating the underlying molecular pathways
Published in Acta Physiologica (01-06-2020)“…Aim Loss of skeletal muscle mass is a common clinical finding in cancer patients. The purpose of this meta‐analysis and systematic review was to quantify the…”
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Enhanced low-threshold motor unit capacity during endurance tasks in patients with spinal muscular atrophy using pyridostigmine
Published in Clinical neurophysiology (01-10-2023)“…•Surface electromyography (sEMG) signals from upper extremity muscles are recorded in 31 patients with spinal muscular atrophy (SMA) treated with…”
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Motor unit reserve capacity in spinal muscular atrophy during fatiguing endurance performance
Published in Clinical neurophysiology (01-03-2021)“…•Surface EMG signals from extremity muscles are recorded in a large cohort (n = 70) of spinal muscular atrophy (SMA) patients.•EMG signal amplitude during…”
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Oxidative ATP synthesis in skeletal muscle is controlled by substrate feedback
Published in American Journal of Physiology: Cell Physiology (01-01-2007)“…Data from (31)P-nuclear magnetic resonance spectroscopy of human forearm flexor muscle were analyzed based on a previously developed model of mitochondrial…”
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Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy
Published in Journal of magnetic resonance imaging (01-08-2021)“…Background Proton magnetic resonance spectroscopy (1H‐MRS) of the human heart is deemed to be a quantitative method to investigate myocardial metabolite…”
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CrossTalk opposing view: Skeletal muscle oxidative capacity is not altered in cystic fibrosis patients
Published in The Journal of physiology (01-03-2017)Get full text
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9
Multi‐parametric quantitative magnetic resonance imaging of the upper arm muscles of patients with spinal muscular atrophy
Published in NMR in biomedicine (01-07-2022)“…Quantitative magnetic resonance imaging (qMRI) is frequently used to map the disease state and disease progression in the lower extremity muscles of patients…”
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Prediction of muscle energy states at low metabolic rates requires feedback control of mitochondrial respiratory chain activity by inorganic phosphate
Published in PloS one (28-03-2012)“…The regulation of the 100-fold dynamic range of mitochondrial ATP synthesis flux in skeletal muscle was investigated. Hypotheses of key control mechanisms were…”
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Fiber-type-specific sensitivities and phenotypic adaptations to dietary fat overload differentially impact fast- versus slow-twitch muscle contractile function in C57BL/6J mice
Published in The Journal of nutritional biochemistry (01-02-2015)“…High-fat diets (HFDs) have been shown to interfere with skeletal muscle energy metabolism and cause peripheral insulin resistance. However, understanding of…”
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Nutritional ketosis improves exercise metabolism in patients with very long‐chain acyl‐CoA dehydrogenase deficiency
Published in Journal of inherited metabolic disease (01-07-2020)“…A maladaptive shift from fat to carbohydrate (CHO) oxidation during exercise is thought to underlie myopathy and exercise‐induced rhabdomyolysis in patients…”
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13
Magnetic Resonance-Compatible Arm-Crank Ergometry: A New Platform Linking Whole-Body Calorimetry to Upper-Extremity Biomechanics and Arm Muscle Metabolism
Published in Frontiers in physiology (19-02-2021)“…Evaluation of the effect of human upper-body training regimens may benefit from knowledge of local energy expenditure in arm muscles. To that end, we developed…”
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Effects of acute nutritional ketosis during exercise in adults with glycogen storage disease type IIIa are phenotype‐specific: An investigator‐initiated, randomized, crossover study
Published in Journal of inherited metabolic disease (01-01-2021)“…Glycogen storage disease type IIIa (GSDIIIa) is an inborn error of carbohydrate metabolism caused by a debranching enzyme deficiency. A subgroup of GSDIIIa…”
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Differential effects of short- and long-term high-fat diet feeding on hepatic fatty acid metabolism in rats
Published in Biochimica et biophysica acta (01-07-2011)“…Imbalance in the supply and utilization of fatty acids (FA) is thought to contribute to intrahepatic lipid (IHL) accumulation in obesity. The aim of this study…”
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ACTIVE MUSCLE MASS AFFECTS ENDURANCE PHYSIOLOGY: A REVIEW ON SINGLE VERSUS DOUBLE-LEG CYCLING
Published in Kinesiology (01-03-2018)“…This review gives an overview of methods and outcomes of studies that compared circulatory, ventilatory, energetic or hormonal responses evoked by single-leg…”
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Muscle Metabolic Responses During Dynamic In-Magnet Exercise Testing: A Pilot Study in Children with an Idiopathic Inflammatory Myopathy
Published in Academic radiology (01-11-2015)“…The clinical utility of supine in-magnet bicycling in combination with phosphorus magnetic resonance spectroscopy ((31)P MRS) to evaluate quadriceps muscle…”
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Cardiac and intramuscular adaptations following short-term exercise prehabilitation in unfit patients scheduled to undergo hepatic or pancreatic surgery: study protocol of a multinuclear MRI study
Published in BMJ open gastroenterology (23-11-2023)“…IntroductionShort-term exercise prehabilitation programmes have demonstrated promising results in improving aerobic capacity of unfit patients prior to major…”
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An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing
Published in Magnetic resonance in medicine (01-01-2010)“…An MR‐compatible ergometer was developed for in‐magnet whole‐body human exercise testing. Designed on the basis of conventional mechanically braked bicycle…”
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Magnitude and control of mitochondrial sensitivity to ADP
Published in American journal of physiology: endocrinology and metabolism (01-09-2009)“…The transduction function for ADP stimulation of mitochondrial ATP synthesis in skeletal muscle was reconstructed in vivo and in silico to investigate the…”
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